Crystal structures of human soluble adenylyl cyclase reveal mechanisms of catalysis and of its activation through bicarbonate

Mitochondrial Ca2+ Uptake Induces Cyclic AMP Generation in the Matrix and Modulates Organelle ATP Levels

(2013) Giulietta Di Benedetto et al.   Cell Metabolism

CO2/HCO3−- and Calcium-regulated Soluble Adenylyl Cyclase as a Physiological ATP Sensor

(2013) Jonathan H. Zippin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of a haem domain in human soluble adenylate cyclase

(2012) Sabine Middelhaufe et al.   BIOSCIENCE REPORTS

SH3 domain ligand binding: What's the consensus and where's the specificity?

(2012) Kalle Saksela et al.   FEBS LETTERS

Type 10 Soluble Adenylyl Cyclase Is Overexpressed in Prostate Carcinoma and Controls Proliferation of Prostate Cancer Cells

(2012) Jan-Paul Flacke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Facilities for macromolecular crystallography at the Helmholtz-Zentrum Berlin

(2012) Uwe Mueller et al.   JOURNAL OF SYNCHROTRON RADIATION

Spatial control of cAMP signalling in health and disease

(2011) Manuela Zaccolo   CURRENT OPINION IN PHARMACOLOGY

Intracellular cAMP signaling by soluble adenylyl cyclase

(2011) Martin Tresguerres et al.   KIDNEY INTERNATIONAL

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Soluble Adenylyl Cyclase Defines a Nuclear cAMP Microdomain in Keratinocyte Hyperproliferative Skin Diseases

(2010) Jonathan H. Zippin et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Physiological carbon dioxide, bicarbonate, and pH sensing

(2010) Martin Tresguerres et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

CO2 Acts as a Signalling Molecule in Populations of the Fungal Pathogen Candida albicans

(2010) Rebecca A. Hall et al.   PLoS Pathogens

Structural Basis for Inhibition of Mammalian Adenylyl Cyclase by Calcium†

(2009) Tung-Chung Mou et al.   BIOCHEMISTRY

Cyclic AMP Produced inside Mitochondria Regulates Oxidative Phosphorylation

(2009) Rebeca Acin-Perez et al.   Cell Metabolism

Capturing adenylyl cyclases as potential drug targets

(2009) Sandra Pierre et al.   NATURE REVIEWS DRUG DISCOVERY

Glucose and GLP-1 Stimulate cAMP Production via Distinct Adenylyl Cyclases in INS-1E Insulinoma Cells

(2008) Lavoisier S. Ramos et al.   JOURNAL OF GENERAL PHYSIOLOGY

Structure-Based Development of Novel Adenylyl Cyclase Inhibitors

(2008) Christine Schlicker et al.   JOURNAL OF MEDICINAL CHEMISTRY

Crystal structure of the guanylyl cyclase Cya2

(2008) A. Rauch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA