Prostatic inflammation enhances basal-to-luminal differentiation and accelerates initiation of prostate cancer with a basal cell origin

Conditionally Ablated Pten in Prostate Basal Cells Promotes Basal-to-Luminal Differentiation and Causes Invasive Prostate Cancer in Mice

(2013) Tsai-Ling Lu et al.   AMERICAN JOURNAL OF PATHOLOGY

Lineage analysis of basal epithelial cells reveals their unexpected plasticity and supports a cell-of-origin model for prostate cancer heterogeneity

(2013) Zhu A. Wang et al.   NATURE CELL BIOLOGY

Prostate cancer originating in basal cells progresses to adenocarcinoma propagated by luminal-like cells

(2013) T. Stoyanova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adult Murine Prostate Basal and Luminal Cells Are Self-Sustained Lineages that Can Both Serve as Targets for Prostate Cancer Initiation

(2012) Nahyun Choi et al.   CANCER CELL

Notch and TGFβ Form a Reciprocal Positive Regulatory Loop that Suppresses Murine Prostate Basal Stem/Progenitor Cell Activity

(2012) Joseph M. Valdez et al.   Cell Stem Cell

Multipotent and unipotent progenitors contribute to prostate postnatal development

(2012) Marielle Ousset et al.   NATURE CELL BIOLOGY

Association of the Innate Immunity and Inflammation Pathway with Advanced Prostate Cancer Risk

(2012) Rémi Kazma et al.   PLoS One

In situ lineage tracking of human prostatic epithelial stem cell fate reveals a common clonal origin for basal and luminal cells

(2011) John K Blackwood et al.   JOURNAL OF PATHOLOGY

Regenerated Luminal Epithelial Cells Are Derived from Preexisting Luminal Epithelial Cells in Adult Mouse Prostate

(2011) June Liu et al.   MOLECULAR ENDOCRINOLOGY

Acute bacterial inflammation of the mouse prostate

(2011) Bayli J. Boehm et al.   PROSTATE

An inducible model of abacterial prostatitis induces antigen specific inflammatory and proliferative changes in the murine prostate

(2011) Jessica M. Haverkamp et al.   PROSTATE

Loss of Nkx3.1 Expression in Bacterial Prostatitis

(2010) May Khalili et al.   AMERICAN JOURNAL OF PATHOLOGY

Immunity, Inflammation, and Cancer

(2010) Sergei I. Grivennikov et al.   CELL

E-cadherin-mediated survival of androgen-receptor-expressing secretory prostate epithelial cells derived from a stratified in vitro differentiation model

(2010) L. E. Lamb et al.   JOURNAL OF CELL SCIENCE

Basal epithelial stem cells are efficient targets for prostate cancer initiation

(2010) D. A. Lawson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of a Cell of Origin for Human Prostate Cancer

(2010) A. S. Goldstein et al.   SCIENCE

Generation of a prostate from a single adult stem cell

(2008) Kevin G. Leong et al.   NATURE

Trop2 identifies a subpopulation of murine and human prostate basal cells with stem cell characteristics

(2008) A. S. Goldstein et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA