Discovery of a selective NaV1.7 inhibitor from centipede venom with analgesic efficacy exceeding morphine in rodent pain models
出版年份 2013 全文链接
标题
Discovery of a selective NaV1.7 inhibitor from centipede venom with analgesic efficacy exceeding morphine in rodent pain models
作者
关键词
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出版物
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 110, Issue 43, Pages 17534-17539
出版商
Proceedings of the National Academy of Sciences
发表日期
2013-10-01
DOI
10.1073/pnas.1306285110
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Spider-Venom Peptides: Structure, Pharmacology, and Potential for Control of Insect Pests
- (2012) Glenn F. King et al. Annual Review of Entomology
- Localization of Nav1.7 in the normal and injured rodent olfactory system indicates a critical role in olfaction, pheromone sensing and immune function
- (2012) Darshani B. Rupasinghe et al. Channels
- Anti-inflammatory effects and acute toxicity of hydroethanolic extract of Jacaranda decurrens roots in adult male rats
- (2012) Joyce Alencar Santos et al. JOURNAL OF ETHNOPHARMACOLOGY
- The Economic Costs of Pain in the United States
- (2012) Darrell J. Gaskin et al. JOURNAL OF PAIN
- Chemical Punch Packed in Venoms Makes Centipedes Excellent Predators
- (2012) Shilong Yang et al. MOLECULAR & CELLULAR PROTEOMICS
- Sea-Anemone Toxin ATX-II Elicits A-Fiber-Dependent Pain and Enhances Resurgent and Persistent Sodium Currents in Large Sensory Neurons
- (2012) Alexandra B Klinger et al. Molecular Pain
- Expression of Nav1.7 in DRG Neurons Extends from Peripheral Terminals in the Skin to Central Preterminal Branches and Terminals in the Dorsal Horn
- (2012) Joel A Black et al. Molecular Pain
- Spider-venom peptides that target voltage-gated sodium channels: Pharmacological tools and potential therapeutic leads
- (2012) Julie K. Klint et al. TOXICON
- Distinct Nav1.7-dependent pain sensations require different sets of sensory and sympathetic neurons
- (2012) Michael S. Minett et al. Nature Communications
- Analgesic and anti-inflammatory effects of the amphibian neurotoxin, anntoxin
- (2011) Lin Wei et al. BIOCHIMIE
- Venoms as a platform for human drugs: translating toxins into therapeutics
- (2011) Glenn F King EXPERT OPINION ON BIOLOGICAL THERAPY
- Molecular basis of the tarantula toxin jingzhaotoxin-III (β-TRTX-Cj1α) interacting with voltage sensors in sodium channel subtype Nav1.5
- (2011) Mingqiang Rong et al. FASEB JOURNAL
- Loss-of-function mutations in sodium channel Nav1.7 cause anosmia
- (2011) Jan Weiss et al. NATURE
- The crystal structure of a voltage-gated sodium channel
- (2011) Jian Payandeh et al. NATURE
- -Conotoxins that differentially block sodium channels NaV1.1 through 1.8 identify those responsible for action potentials in sciatic nerve
- (2011) M. J. Wilson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- On the venom system of centipedes (Chilopoda), a neglected group of venomous animals
- (2011) Eivind A.B. Undheim et al. TOXICON
- Peptide toxins that selectively target insect NaVand CaVchannels
- (2010) Glenn F. King et al. Channels
- Pain perception is altered by a nucleotide polymorphism in SCN9A
- (2010) F. Reimann et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- NMR methods for determining disulfide-bond connectivities
- (2010) Mehdi Mobli et al. TOXICON
- Subtype-selective targeting of voltage-gated sodium channels
- (2009) Steve England et al. BRITISH JOURNAL OF PHARMACOLOGY
- Cellular and Molecular Mechanisms of Pain
- (2009) Allan I. Basbaum et al. CELL
- Targeting voltage-gated sodium channels for pain therapy
- (2009) Jeffrey J Clare EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Expression and characterization of jingzhaotoxin-34, a novel neurotoxin from the venom of the tarantula Chilobrachys jingzhao
- (2009) Jinjun Chen et al. PEPTIDES
- ProTx-II, a Selective Inhibitor of NaV1.7 Sodium Channels, Blocks Action Potential Propagation in Nociceptors
- (2008) W. A. Schmalhofer et al. MOLECULAR PHARMACOLOGY
- Deconstructing voltage sensor function and pharmacology in sodium channels
- (2008) Frank Bosmans et al. NATURE
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