标题
Mechanism for activation of mutated epidermal growth factor receptors in lung cancer
作者
关键词
-
出版物
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 110, Issue 38, Pages E3595-E3604
出版商
Proceedings of the National Academy of Sciences
发表日期
2013-09-10
DOI
10.1073/pnas.1220050110
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Conformational Coupling across the Plasma Membrane in Activation of the EGF Receptor
- (2013) Nicholas F. Endres et al. CELL
- Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization
- (2012) Yibing Shan et al. CELL
- Insights into the Aberrant Activity of Mutant EGFR Kinase Domain and Drug Recognition
- (2012) Ketan S. Gajiwala et al. STRUCTURE
- Sos-mediated cross-activation of wild-type Ras by oncogenic Ras is essential for tumorigenesis
- (2012) Hao-Hsuan Jeng et al. Nature Communications
- Oncogenic and Wild-type Ras Play Divergent Roles in the Regulation of Mitogen-Activated Protein Kinase Signaling
- (2012) Amy Young et al. Cancer Discovery
- HER2 Amplification: A Potential Mechanism of Acquired Resistance to EGFR Inhibition in EGFR -Mutant Lung Cancers That Lack the Second-Site EGFR T790M Mutation
- (2012) Ken Takezawa et al. Cancer Discovery
- Regulation of the catalytic activity of the EGF receptor
- (2011) Nicholas F Endres et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Mechanistic insights into the activation of oncogenic forms of EGF receptor
- (2011) Zhihong Wang et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Features and development ofCoot
- (2010) P. Emsley et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Cell Signaling by Receptor Tyrosine Kinases
- (2010) Mark A. Lemmon et al. CELL
- Epidermal growth factor receptor tyrosine kinase inhibitors as first-line treatment in advanced nonsmall-cell lung cancer
- (2010) Rafael Rosell et al. CURRENT OPINION IN ONCOLOGY
- Super-resolution biomolecular crystallography with low-resolution data
- (2010) Gunnar F. Schröder et al. NATURE
- Gefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): an open label, randomised phase 3 trial
- (2009) Tetsuya Mitsudomi et al. LANCET ONCOLOGY
- Novel mutant-selective EGFR kinase inhibitors against EGFR T790M
- (2009) Wenjun Zhou et al. NATURE
- Gefitinib or Carboplatin–Paclitaxel in Pulmonary Adenocarcinoma
- (2009) Tony S. Mok et al. NEW ENGLAND JOURNAL OF MEDICINE
- Structural analysis of the catalytically inactive kinase domain of the human EGF receptor 3
- (2009) N. Jura et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Impact of Common Epidermal Growth Factor Receptor and HER2 Variants on Receptor Activity and Inhibition by Lapatinib
- (2008) T. M. Gilmer et al. CANCER RESEARCH
- Lung adenocarcinoma: guiding EGFR-targeted therapy and beyond
- (2008) Marc Ladanyi et al. MODERN PATHOLOGY
- BIBW2992, an irreversible EGFR/HER2 inhibitor highly effective in preclinical lung cancer models
- (2008) D Li et al. ONCOGENE
- The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP
- (2008) C.-H. Yun et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mechanism of Activation and Inhibition of the HER4/ErbB4 Kinase
- (2008) Chen Qiu et al. STRUCTURE
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