Chemical polysialylation of human recombinant butyrylcholinesterase delivers a long-acting bioscavenger for nerve agents in vivo

The proline-rich tetramerization peptides in equine serum butyrylcholinesterase

(2012) Kevser Biberoglu et al.   FEBS Journal

Pretreatment with human serum butyrylcholinesterase alone prevents cardiac abnormalities, seizures, and death in Göttingen minipigs exposed to sarin vapor

(2011) Ashima Saxena et al.   BIOCHEMICAL PHARMACOLOGY

Protective efficacy of catalytic bioscavenger, paraoxonase 1 against sarin and soman exposure in guinea pigs

(2011) Manojkumar Valiyaveettil et al.   BIOCHEMICAL PHARMACOLOGY

Directed evolution of hydrolases for prevention of G-type nerve agent intoxication

(2011) Rinkoo D Gupta et al.   Nature Chemical Biology

Reactibodies generated by kinetic selection couple chemical reactivity with favorable protein dynamics

(2011) I. Smirnov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hydrolysis potential of recombinant human skin and kidney prolidase against diisopropylfluorophosphate and sarin by in vitro analysis

(2011) Michael Costante et al.   TOXICOLOGY IN VITRO

Organophosphate hydrolases as catalytic bioscavengers of organophosphorus nerve agents

(2011) Marie Trovaslet-Leroy et al.   TOXICOLOGY LETTERS

Modulating the pharmacokinetics of therapeutic antibodies

(2010) A. Constantinou et al.   BIOTECHNOLOGY LETTERS

Demonstration of in vivo stability and lack of immunogenicity of a polyethyleneglycol-conjugated recombinant CHO-derived butyrylcholinesterase bioscavenger using a homologous macaque model

(2010) Yvonne J. Rosenberg et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Plant-derived human butyrylcholinesterase, but not an organophosphorous-compound hydrolyzing variant thereof, protects rodents against nerve agents

(2010) B. C. Geyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal Structures of Brain Group-VIII Phospholipase A2 in Nonaged Complexes with the Organophosphorus Nerve Agents Soman and Sarin†,‡

(2009) Todd M. Epstein et al.   BIOCHEMISTRY

Structure, Activities and Biomedical Applications of Human Butyrylcholinesterase

(2009) Patrick Masson et al.   PROTEIN AND PEPTIDE LETTERS

Lamellipodin proline rich peptides associated with native plasma butyrylcholinesterase tetramers

(2008) He Li et al.   BIOCHEMICAL JOURNAL

Effect of polyethylene glycol modification on the circulatory stability and immunogenicity of recombinant human butyrylcholinesterase

(2008) Nageswararao Chilukuri et al.   CHEMICO-BIOLOGICAL INTERACTIONS

A collaborative endeavor to design cholinesterase-based catalytic scavengers against toxic organophosphorus esters

(2008) Patrick Masson et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Pseudo-esterase Activity of Human Albumin

(2008) Oksana Lockridge et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human Recombinant Butyrylcholinesterase Purified from the Milk of Transgenic Goats Interacts with Beta-Amyloid Fibrils and Suppresses Their Formation in vitro

(2008) E. Podoly et al.   Neurodegenerative Diseases

Binding and Hydrolysis of Soman by Human Serum Albumin

(2007) Bin Li et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Management of acute organophosphorus pesticide poisoning

(2007) Michael Eddleston et al.   LANCET