Innate pro-B-cell progenitors protect against type 1 diabetes by regulating autoimmune effector T cells

Release from Regulatory T Cell-Mediated Suppression during the Onset of Tissue-Specific Autoimmunity Is Associated with Elevated IL-21

(2014) L. E. Clough et al.   JOURNAL OF IMMUNOLOGY

T-bet and Eomesodermin Play Critical Roles in Directing T Cell Differentiation to Th1 versus Th17

(2014) Y. Yang et al.   JOURNAL OF IMMUNOLOGY

B Lymphocytes Promote Expansion of Regulatory T Cells in Oral Tolerance: Powerful Induction by Antigen Coupled to Cholera Toxin B Subunit

(2014) J.-B. Sun et al.   JOURNAL OF IMMUNOLOGY

Immune Regulatory Function of B Cells

(2012) Claudia Mauri et al.   Annual Review of Immunology

Interleukin-21 Receptor-Mediated Signals Control Autoreactive T Cell Infiltration in Pancreatic Islets

(2012) Tom L. Van Belle et al.   IMMUNITY

Regulatory B cells control T-cell autoimmunity through IL-21-dependent cognate interactions

(2012) Ayumi Yoshizaki et al.   NATURE

Interleukin-21 Is Critically Required in Autoimmune and Allogeneic Responses to Islet Tissue in Murine Models

(2011) Helen M. McGuire et al.   DIABETES

Immunological Applications of Stem Cells in Type 1 Diabetes

(2011) Paolo Fiorina et al.   ENDOCRINE REVIEWS

Novel regulatory functions for Toll-like receptor-activated B cells during intracellular bacterial infection

(2011) Simon Fillatreau   IMMUNOLOGICAL REVIEWS

Long-Term Allograft Tolerance Is Characterized by the Accumulation of B Cells Exhibiting an Inhibited Profile

(2010) L. Le Texier et al.   AMERICAN JOURNAL OF TRANSPLANTATION

B10 cells and regulatory B cells balance immune responses during inflammation, autoimmunity, and cancer

(2010) David J. DiLillo et al.   Annals of the New York Academy of Sciences

Identification of a B cell signature associated with renal transplant tolerance in humans

(2010) Kenneth A. Newell et al.   JOURNAL OF CLINICAL INVESTIGATION

TLR9 Blockade Inhibits Activation of Diabetogenic CD8+ T Cells and Delays Autoimmune Diabetes

(2010) Y. Zhang et al.   JOURNAL OF IMMUNOLOGY

IL25 elicits a multipotent progenitor cell population that promotes TH2 cytokine responses

(2010) Steven A. Saenz et al.   NATURE

Systemic Toll-Like Receptor Stimulation Suppresses Experimental Allergic Asthma and Autoimmune Diabetes in NOD Mice

(2010) Aude Aumeunier et al.   PLoS One

Interleukin-21 Is Required for the Development of Type 1 Diabetes in NOD Mice

(2009) A. P.R. Sutherland et al.   DIABETES

Suppressive functions of activated B cells in autoimmune diseases reveal the dual roles of Toll-like receptors in immunity

(2009) Vicky Lampropoulou et al.   IMMUNOLOGICAL REVIEWS

Killer B lymphocytes: the evidence and the potential

(2009) Steven K. Lundy   INFLAMMATION RESEARCH

B Cell Intrinsic MyD88 Signals Drive IFN-  Production from T Cells and Control Switching to IgG2c

(2009) T. A. Barr et al.   JOURNAL OF IMMUNOLOGY

The Development and Function of Regulatory B Cells Expressing IL-10 (B10 Cells) Requires Antigen Receptor Diversity and TLR Signals

(2009) K. Yanaba et al.   JOURNAL OF IMMUNOLOGY

Selective Targeting of B Cells with Agonistic Anti-CD40 Is an Efficacious Strategy for the Generation of Induced Regulatory T2-Like B Cells and for the Suppression of Lupus in MRL/lpr Mice

(2009) P. A. Blair et al.   JOURNAL OF IMMUNOLOGY

The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17–producing effector T helper cells in vivo

(2009) Mandy J McGeachy et al.   NATURE IMMUNOLOGY

Loss of parity between IL-2 and IL-21 in the NOD Idd3 locus

(2009) H. M. McGuire et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interleukin-21 as a new therapeutic target for immune-mediated diseases

(2009) Giovanni Monteleone et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Lymphoid precursors are directed to produce dendritic cells as a result of TLR9 ligation during herpes infection

(2008) R. S. Welner et al.   BLOOD

Induction of CD4+ T-cell anergy and apoptosis by activated human B cells

(2008) T. Tretter et al.   BLOOD

Role of GM-CSF in tolerance induction by mobilized hematopoietic progenitors

(2008) H. Kared et al.   BLOOD

Targeting CD22 Reprograms B-Cells and Reverses Autoimmune Diabetes

(2008) P. Fiorina et al.   DIABETES

B-lymphocyte contributions to human autoimmune disease

(2008) Koichi Yanaba et al.   IMMUNOLOGICAL REVIEWS

Regulatory role of B-1 B cells in chronic colitis

(2008) Y. Shimomura et al.   INTERNATIONAL IMMUNOLOGY

Innocuous IFNγ induced by adjuvant-free antigen restores normoglycemia in NOD mice through inhibition of IL-17 production

(2008) Renu Jain et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Autologous and allogeneic hematopoietic stem cell transplantation for Multiple Sclerosis: Perspective on mechanisms of action

(2008) Bart Van Wijmeersch et al.   JOURNAL OF NEUROIMMUNOLOGY

The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells

(2008) Aurelie T Bauquet et al.   NATURE IMMUNOLOGY

The defect in T-cell regulation in NOD mice is an effect on the T-cell effectors

(2008) A. M. D'Alise et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IL-21 signaling is critical for the development of type I diabetes in the NOD mouse

(2008) R. Spolski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA