PML mediates glioblastoma resistance to mammalian target of rapamycin (mTOR)-targeted therapies
出版年份 2013 全文链接
标题
PML mediates glioblastoma resistance to mammalian target of rapamycin (mTOR)-targeted therapies
作者
关键词
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出版物
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 110, Issue 11, Pages 4339-4344
出版商
Proceedings of the National Academy of Sciences
发表日期
2013-02-26
DOI
10.1073/pnas.1217602110
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Translation-dependent mechanisms lead to PML upregulation and mediate oncogenic K-RAS-induced cellular senescence
- (2012) Pier Paolo Scaglioni et al. EMBO Molecular Medicine
- A metabolic prosurvival role for PML in breast cancer
- (2012) Arkaitz Carracedo et al. JOURNAL OF CLINICAL INVESTIGATION
- Phase I study of arsenic trioxide and temozolomide in combination with radiation therapy in patients with malignant gliomas
- (2012) Sean A. Grimm et al. JOURNAL OF NEURO-ONCOLOGY
- A PML–PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance
- (2012) Keisuke Ito et al. NATURE MEDICINE
- Transcriptional Control of Cellular Metabolism by mTOR Signaling
- (2011) J. L. Yecies et al. CANCER RESEARCH
- Pml represses tumour progression through inhibition of mTOR
- (2011) Rosa Bernardi et al. EMBO Molecular Medicine
- Activation of Src induces mitochondrial localisation of de2-7EGFR (EGFRvIII) in glioma cells: implications for glucose metabolism
- (2011) Anna N. Cvrljevic et al. JOURNAL OF CELL SCIENCE
- Curing APL through PML/RARA degradation by As2O3
- (2011) Valerie Lallemand-Breitenbach et al. TRENDS IN MOLECULAR MEDICINE
- Oncogenic EGFR Signaling Activates an mTORC2-NF- B Pathway That Promotes Chemotherapy Resistance
- (2011) K. Tanaka et al. Cancer Discovery
- Arsenic Trioxide Controls the Fate of the PML-RAR Oncoprotein by Directly Binding PML
- (2010) X. W. Zhang et al. SCIENCE
- Fyn and Src Are Effectors of Oncogenic Epidermal Growth Factor Receptor Signaling in Glioblastoma Patients
- (2009) K. V. Lu et al. CANCER RESEARCH
- EGFR Signaling Through an Akt-SREBP-1-Dependent, Rapamycin-Resistant Pathway Sensitizes Glioblastomas to Antilipogenic Therapy
- (2009) D. Guo et al. Science Signaling
- PML targeting eradicates quiescent leukaemia-initiating cells
- (2008) Keisuke Ito et al. NATURE
- Comprehensive genomic characterization defines human glioblastoma genes and core pathways
- (2008) Roger McLendon et al. NATURE
- Malignant Gliomas in Adults
- (2008) Patrick Y. Wen et al. NEW ENGLAND JOURNAL OF MEDICINE
- An Integrated Genomic Analysis of Human Glioblastoma Multiforme
- (2008) D. W. Parsons et al. SCIENCE
- Antitumor Activity of Rapamycin in a Phase I Trial for Patients with Recurrent PTEN-Deficient Glioblastoma
- (2008) Tim F Cloughesy et al. PLOS MEDICINE
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