A fundamental protein property, thermodynamic stability, revealed solely from large-scale measurements of protein function

Enrich: software for analysis of protein function by enrichment and depletion of variants

(2011) Douglas M. Fowler et al.   BIOINFORMATICS

Learning sparse models for a dynamic Bayesian network classifier of protein secondary structure

(2011) Zafer Aydin et al.   BMC BIOINFORMATICS

Protein stability by number: high-throughput and statistical approaches to one of protein science's most difficult problems

(2011) Thomas J Magliery et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

A systems analysis of mutational effects in HIV-1 protease and reverse transcriptase

(2011) Trevor Hinkley et al.   NATURE GENETICS

Protein 3D Structure Computed from Evolutionary Sequence Variation

(2011) Debora S. Marks et al.   PLoS One

Experimental illumination of a fitness landscape

(2011) R. T. Hietpas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deep mutational scanning: assessing protein function on a massive scale

(2011) Carlos L. Araya et al.   TRENDS IN BIOTECHNOLOGY

Multiplexed massively parallel SELEX for characterization of human transcription factor binding specificities

(2010) A. Jolma et al.   GENOME RESEARCH

High-resolution mapping of protein sequence-function relationships

(2010) Douglas M Fowler et al.   NATURE METHODS

WW: An isolated three-stranded antiparallel β-sheet domain that unfolds and refolds reversibly; evidence for a structured hydrophobic cluster in urea and GdnHCl and a disordered thermal unfolded state

(2010) Edward K. Koepf et al.   PROTEIN SCIENCE

Optimizing Protein Stability In Vivo

(2009) Linda Foit et al.   MOLECULAR CELL

In the light of directed evolution: Pathways of adaptive protein evolution

(2009) J. D. Bloom et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Assessing computational methods for predicting protein stability upon mutation: good on average but not in the details

(2009) V. Potapov et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Sequence determinants of thermodynamic stability in a WW domain-An all-β-sheet protein

(2009) Marcus Jäger et al.   PROTEIN SCIENCE

Inferring Stabilizing Mutations from Protein Phylogenies: Application to Influenza Hemagglutinin

(2009) Jesse D. Bloom et al.   PLoS Computational Biology

Inferring Binding Energies from Selected Binding Sites

(2009) Yue Zhao et al.   PLoS Computational Biology

Defining genetic interaction

(2008) R. Mani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Increasing protein stability using a rational approach combining sequence homology and structural alignment: Stabilizing the WW domain

(2002) Xin Jiang et al.   PROTEIN SCIENCE