Signaling axis involving Hedgehog, Notch, and Scl promotes the embryonic endothelial-to-hematopoietic transition

Targeting hedgehog in hematologic malignancy

(2012) D. A. Irvine et al.   BLOOD

Erythroid/Myeloid Progenitors and Hematopoietic Stem Cells Originate from Distinct Populations of Endothelial Cells

(2011) Michael J. Chen et al.   Cell Stem Cell

Scl isoforms act downstream of etsrp to specify angioblasts and definitive hematopoietic stem cells

(2010) X. Ren et al.   BLOOD

Application of induced pluripotent stem cells to hematologic disease

(2010) Peter Geon Kim et al.   CYTOTHERAPY

Hedgehog Signaling Is Dispensable for Adult Hematopoietic Stem Cell Function

(2009) Jie Gao et al.   Cell Stem Cell

Hedgehog Signaling Is Dispensable for Adult Murine Hematopoietic Stem Cell Function and Hematopoiesis

(2009) Inga Hofmann et al.   Cell Stem Cell

Ventral embryonic tissues and Hedgehog proteins induce early AGM hematopoietic stem cell development

(2009) M. Peeters et al.   DEVELOPMENT

Hedgehog and Bmp Polarize Hematopoietic Stem Cell Emergence in the Zebrafish Dorsal Aorta

(2009) Robert N. Wilkinson et al.   DEVELOPMENTAL CELL

The Molecular Basis of Vascular Lumen Formation in the Developing Mouse Aorta

(2009) Boris Strilić et al.   DEVELOPMENTAL CELL

Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter

(2009) Michael J. Chen et al.   NATURE

Continuous single-cell imaging of blood generation from haemogenic endothelium

(2009) Hanna M. Eilken et al.   NATURE

The haemangioblast generates haematopoietic cells through a haemogenic endothelium stage

(2009) Christophe Lancrin et al.   NATURE

Restoration of Runx1 Expression in the Tie2 Cell Compartment Rescues Definitive Hematopoietic Stem Cells and Extends Life of Runx1 Knockout Animals Until Birth

(2009) Anna Liakhovitskaia et al.   STEM CELLS

Modulation of murine embryonic stem cell-derived CD41+c-kit+ hematopoietic progenitors by ectopic expression of Cdx genes

(2008) S. L. McKinney-Freeman et al.   BLOOD

Extensive Hematopoietic Stem Cell Generation in the AGM Region via Maturation of VE-Cadherin+CD45+ Pre-Definitive HSCs

(2008) Samir Taoudi et al.   Cell Stem Cell

BMP and Wnt Specify Hematopoietic Fate by Activation of the Cdx-Hox Pathway

(2008) Claudia Lengerke et al.   Cell Stem Cell

Fate Tracing Reveals the Endothelial Origin of Hematopoietic Stem Cells

(2008) Ann C. Zovein et al.   Cell Stem Cell

Numb mediates the interaction between Wnt and Notch to modulate primitive erythropoietic specification from the hemangioblast

(2008) X. Cheng et al.   DEVELOPMENT

Mesodermal patterning activity of SCL

(2008) Ismail Ismailoglu et al.   EXPERIMENTAL HEMATOLOGY