Investigation of the sodium-binding sites in the sodium-coupled betaine transporter BetP

X-ray structures of LeuT in substrate-free outward-open and apo inward-open states

(2012) Harini Krishnamurthy et al.   NATURE

The Role of Local Hydration and Hydrogen-Bonding Dynamics in Ion and Solute Release from Ion-Coupled Secondary Transporters

(2011) Chunfeng Zhao et al.   BIOCHEMISTRY

Protein folding and binding: from biology to physics and back again

(2011) Michael K Gilson et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Substrate specificity and ion coupling in the Na+/betaine symporter BetP

(2011) Camilo Perez et al.   EMBO JOURNAL

The role of trimerization in the osmoregulated betaine transporter BetP

(2011) Camilo Perez et al.   EMBO REPORTS

Conserved Tyrosine in the First Transmembrane Segment of Solute:Sodium Symporters Is Involved in Na+-coupled Substrate Co-transport

(2011) Sonia Mazier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Asymmetry in a Trimeric Na+/Betaine Symporter, BetP, from Corynebacterium glutamicum

(2011) Ching-Ju Tsai et al.   JOURNAL OF MOLECULAR BIOLOGY

The Alternating-Access Mechanism of MFS Transporters Arises from Inverted-Topology Repeats

(2011) Sebastian Radestock et al.   JOURNAL OF MOLECULAR BIOLOGY

Substrate-modulated gating dynamics in a Na+-coupled neurotransmitter transporter homologue

(2011) Yongfang Zhao et al.   NATURE

A Study of the Evolution of Inverted-Topology Repeats from LeuT-Fold Transporters Using AlignMe

(2010) Kamil Khafizov et al.   BIOCHEMISTRY

The structural basis of secondary active transport mechanisms

(2010) Lucy R. Forrest et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Water Permeation through the Sodium-Dependent Galactose Cotransporter vSGLT

(2010) Seungho Choe et al.   BIOPHYSICAL JOURNAL

Conformational Rearrangements to the Intracellular Open States of the LeuT and ApcT Transporters Are Modulated by Common Mechanisms

(2010) Lei Shi et al.   BIOPHYSICAL JOURNAL

The sodium/galactose symporter crystal structure is a dynamic, not so occluded state

(2010) Elia Zomot et al.   Molecular BioSystems

Single-molecule dynamics of gating in a neurotransmitter transporter homologue

(2010) Yongfang Zhao et al.   NATURE

Structural basis of Na+-independent and cooperative substrate/product antiport in CaiT

(2010) Sabrina Schulze et al.   NATURE

The mechanism of sodium and substrate release from the binding pocket of vSGLT

(2010) Akira Watanabe et al.   NATURE

Ion/substrate-dependent conformational dynamics of a bacterial homolog of neurotransmitter:sodium symporters

(2010) Derek P Claxton et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Crystal structure of the carnitine transporter and insights into the antiport mechanism

(2010) Lin Tang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Evidence for a third sodium-binding site in glutamate transporters suggests an ion/substrate coupling model

(2010) H. P. Larsson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Basis of Alternating Access Membrane Transport by the Sodium-Hydantoin Transporter Mhp1

(2010) T. Shimamura et al.   SCIENCE

Modeling and Dynamics of the Inward-Facing State of a Na+/Cl− Dependent Neurotransmitter Transporter Homologue

(2010) Saher Afshan Shaikh et al.   PLoS Computational Biology

Ion-Releasing State of a Secondary Membrane Transporter

(2009) Jing Li et al.   BIOPHYSICAL JOURNAL

Complete Ion-Coordination Structure in the Rotor Ring of Na+-Dependent F-ATP Synthases

(2009) Thomas Meier et al.   JOURNAL OF MOLECULAR BIOLOGY

Molecular basis of transport and regulation in the Na+/betaine symporter BetP

(2009) Susanne Ressl et al.   NATURE

The Rocking Bundle: A Mechanism for Ion-Coupled Solute Flux by Symmetrical Transporters

(2009) Lucy R. Forrest et al.   PHYSIOLOGY

Inward-facing conformation of glutamate transporters as revealed by their inverted-topology structural repeats

(2009) T. J. Crisman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure and Mechanism of a Na+-Independent Amino Acid Transporter

(2009) P. L. Shaffer et al.   SCIENCE

Regulatory Properties and Interaction of the C- and N-Terminal Domains of BetP, an Osmoregulated Betaine Transporter fromCorynebacterium glutamicum†

(2008) Vera Ott et al.   BIOCHEMISTRY

Control of Ion Selectivity in LeuT: Two Na+ Binding Sites with Two Different Mechanisms

(2008) Sergei Y. Noskov et al.   JOURNAL OF MOLECULAR BIOLOGY

Function of Transmembrane Domain IX in the Na+/Proline Transporter PutP

(2008) Michael Raba et al.   JOURNAL OF MOLECULAR BIOLOGY

SSM-based electrophysiology

(2008) Patrick Schulz et al.   METHODS

The Mechanism of a Neurotransmitter:Sodium Symporter—Inward Release of Na+ and Substrate Is Triggered by Substrate in a Second Binding Site

(2008) Lei Shi et al.   MOLECULAR CELL

Mechanism for alternating access in neurotransmitter transporters

(2008) L. R. Forrest et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure and Molecular Mechanism of a Nucleobase-Cation-Symport-1 Family Transporter

(2008) S. Weyand et al.   SCIENCE

The Crystal Structure of a Sodium Galactose Transporter Reveals Mechanistic Insights into Na+/Sugar Symport

(2008) S. Faham et al.   SCIENCE

Substrate Binding and Formation of an Occluded State in the Leucine Transporter

(2007) Leyla Celik et al.   BIOPHYSICAL JOURNAL