Preparation of unnatural N-to-N and C-to-C protein fusions

Synthesis of Heterobifunctional Protein Fusions Using Copper-Free Click Chemistry and the Aldehyde Tag

(2012) Jason E. Hudak et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Making and Breaking Peptide Bonds: Protein Engineering Using Sortase

(2011) Maximilian Wei-Lin Popp et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Click synthesis of ubiquitin dimer analogs to interrogate linkage-specific UBA domain binding

(2011) Nadine D. Weikart et al.   CHEMICAL COMMUNICATIONS

Identification of host cell factors required for intoxication through use of modified cholera toxin

(2011) Carla P. Guimaraes et al.   JOURNAL OF CELL BIOLOGY

A MCP1 fusokine with CCR2-specific tumoricidal activity

(2011) Moutih Rafei et al.   Molecular Cancer

Generation of protein lattices by fusing proteins with matching rotational symmetry

(2011) John C. Sinclair et al.   Nature Nanotechnology

A general chemical synthesis platform for crosslinking multivalent single chain variable fragments

(2011) Joan G. Schellinger et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Monomeric and dimeric CXCL12 inhibit metastasis through distinct CXCR4 interactions and signaling pathways

(2011) L. J. Drury et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Site-Specific Incorporation ofp-Propargyloxyphenylalanine in a Cell-Free Environment for Direct Protein−Protein Click Conjugation

(2010) Bradley C. Bundy et al.   BIOCONJUGATE CHEMISTRY

Synthesis of N-Terminally Linked Protein and Peptide Dimers by Native Chemical Ligation

(2010) Junpeng Xiao et al.   BIOCONJUGATE CHEMISTRY

Generation of Site-Specific and Enzymatically Stable Conjugates of Recombinant Proteins with Ubiquitin-Like Modifiers by the CuI-Catalyzed Azide-Alkyne Cycloaddition

(2010) Nadine D. Weikart et al.   CHEMBIOCHEM

Re-Engineering Erythropoietin as an IgG Fusion Protein That Penetrates the Blood−Brain Barrier in the Mouse

(2010) Qing-Hui Zhou et al.   MOLECULAR PHARMACEUTICS

IL-8 single-chain homodimers and heterodimers: Interactions with the chemokine receptors CXCR1, CXCR2, and DARC

(2010) Steven R. Leong et al.   PROTEIN SCIENCE

Genetic Engineering of a Bifunctional IgG Fusion Protein with Iduronate-2-Sulfatase

(2009) Jeff Zhiqiang Lu et al.   BIOCONJUGATE CHEMISTRY

Bispecific T-Cell Engaging Antibodies for Cancer Therapy

(2009) P. A. Baeuerle et al.   CANCER RESEARCH

Aza-dibenzocyclooctynes for fast and efficient enzyme PEGylation via copper-free (3+2) cycloaddition

(2009) Marjoke F. Debets et al.   CHEMICAL COMMUNICATIONS

Differential Activation and Regulation of CXCR1 and CXCR2 by CXCL8 Monomer and Dimer

(2009) M. W. Nasser et al.   JOURNAL OF IMMUNOLOGY

Site-Specific N- and C-Terminal Labeling of a Single Polypeptide Using Sortases of Different Specificity

(2009) John M. Antos et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Allosteric communication between protomers of dopamine class A GPCR dimers modulates activation

(2009) Yang Han et al.   Nature Chemical Biology

Modulation of protein properties in living cells using nanobodies

(2009) Axel Kirchhofer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Genetic Engineering, Expression, and Activity of a Chimeric Monoclonal Antibody−Avidin Fusion Protein for Receptor-Mediated Delivery of Biotinylated Drugs in Humans

(2008) Ruben J. Boado et al.   BIOCONJUGATE CHEMISTRY