Agonist binding evokes extensive conformational changes in the extracellular domain of the ATP-gated human P2X1 receptor ion channel

The Intracellular Amino Terminus Plays a Dominant Role in Desensitization of ATP-gated P2X Receptor Ion Channels

(2011) Rebecca C. Allsopp et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cysteine Scanning Mutagenesis (Residues Glu52–Gly96) of the Human P2X1 Receptor for ATP

(2011) Rebecca C. Allsopp et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ion access pathway to the transmembrane pore in P2X receptor channels

(2011) Toshimitsu Kawate et al.   JOURNAL OF GENERAL PHYSIOLOGY

Activation and Regulation of Purinergic P2X Receptor Channels

(2011) C. Coddou et al.   PHARMACOLOGICAL REVIEWS

Agonist trapped in ATP-binding sites of the P2X2 receptor

(2011) R. Jiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Preferential use of unobstructed lateral portals as the access route to the pore of human ATP-gated ion channels (P2X receptors)

(2011) D. S. K. Samways et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural interpretation of P2X receptor mutagenesis studies on drug action

(2010) Richard J Evans   BRITISH JOURNAL OF PHARMACOLOGY

A Putative Extracellular Salt Bridge at the Subunit Interface Contributes to the Ion Channel Function of the ATP-gated P2X2 Receptor

(2010) Ruotian Jiang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

New structure enlivens interest in P2X receptors

(2010) Liam E. Browne et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Contribution of the region Glu181 to Val200 of the extracellular loop of the human P2X1 receptor to agonist binding and gating revealed using cysteine scanning mutagenesis1

(2009) Jonathan A. Roberts et al.   JOURNAL OF NEUROCHEMISTRY

Crystal structure of the ATP-gated P2X4 ion channel in the closed state

(2009) Toshimitsu Kawate et al.   NATURE

P2X receptors: dawn of the post-structure era

(2009) Mark T. Young   TRENDS IN BIOCHEMICAL SCIENCES

Signaling at Purinergic P2X Receptors

(2008) Annmarie Surprenant et al.   Annual Review of Physiology

Molecular Shape, Architecture, and Size of P2X4Receptors Determined Using Fluorescence Resonance Energy Transfer and Electron Microscopy

(2008) Mark T. Young et al.   JOURNAL OF BIOLOGICAL CHEMISTRY