Structure of a hepatitis C virus RNA domain in complex with a translation inhibitor reveals a binding mode reminiscent of riboswitches

Chronic Hepatitis C

(2011) Jae Young Jang et al.   Gut and Liver

Hepatitis C viral protein translation: mechanisms and implications in developing antivirals

(2011) Brett Hoffman et al.   LIVER INTERNATIONAL

Classification of pseudo pairs between nucleotide bases and amino acids by analysis of nucleotide–protein complexes

(2011) Jiro Kondo et al.   NUCLEIC ACIDS RESEARCH

Preexisting drug-resistance mutations reveal unique barriers to resistance for distinct antivirals

(2011) M. Robinson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HCV IRES domain IIb affects the configuration of coding RNA in the 40S subunit's decoding groove

(2011) M. E. Filbin et al.   RNA

First Specific Drugs Raise Hopes for Hepatitis C

(2011) M. Enserink   SCIENCE

Ribozymes and Riboswitches: Modulation of RNA Function by Small Molecules

(2010) Jinwei Zhang et al.   BIOCHEMISTRY

A Modular Approach to Synthetic RNA Binders of the Hepatitis C Virus Internal Ribosome Entry Site

(2010) Maia Carnevali et al.   CHEMBIOCHEM

An Efficient New Route to Dihydropyranobenzimidazole Inhibitors of HCV Replication

(2010) Matthew A. Parker et al.   MOLECULES

Inhibitor-induced structural change in the HCV IRES domain IIa RNA

(2010) R. B. Paulsen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Determination of riboswitch structures: Light at the end of the tunnel?

(2010) Alexander Serganov   RNA Biology

Conformational inhibition of the hepatitis C virus internal ribosome entry site RNA

(2009) Jerod Parsons et al.   Nature Chemical Biology

RNA-Binding Protein hnRNP D Modulates Internal Ribosome Entry Site-Dependent Translation of Hepatitis C Virus RNA

(2008) K. Y. Paek et al.   JOURNAL OF VIROLOGY

Structure and function of HCV IRES domains

(2008) Peter J. Lukavsky   VIRUS RESEARCH

Divergent picornavirus IRES elements

(2008) Graham J. Belsham   VIRUS RESEARCH