Interdomain dynamics and coactivation of the mRNA decapping enzyme Dcp2 are mediated by a gatekeeper tryptophan

Ubiquitin in Motion: Structural Studies of the Ubiquitin-Conjugating Enzyme∼Ubiquitin Conjugate

(2011) Jonathan N. Pruneda et al.   BIOCHEMISTRY

The Mechanism of Linkage-Specific Ubiquitin Chain Elongation by a Single-Subunit E2

(2011) Katherine E. Wickliffe et al.   CELL

A conserved mechanism of DEAD-box ATPase activation by nucleoporins and InsP6 in mRNA export

(2011) Ben Montpetit et al.   NATURE

XUTs are a class of Xrn1-sensitive antisense regulatory non-coding RNA in yeast

(2011) E. L. van Dijk et al.   NATURE

Solution structures of DEAD-box RNA chaperones reveal conformational changes and nucleic acid tethering by a basic tail

(2011) A. L. Mallam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Dynamic Knockout Reveals That Conformational Fluctuations Influence the Chemical Step of Enzyme Catalysis

(2011) G. Bhabha et al.   SCIENCE

Structural and Energetic Mechanisms of Cooperative Autoinhibition and Activation of Vav1

(2010) Bingke Yu et al.   CELL

Mammalian microRNAs predominantly act to decrease target mRNA levels

(2010) Huili Guo et al.   NATURE

A split active site couples cap recognition by Dcp2 to activation

(2010) Stephen N Floor et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Dcp1 links coactivators of mRNA decapping to Dcp2 by proline recognition

(2010) M. S. Borja et al.   RNA

Transient Non-native Hydrogen Bonds Promote Activation of a Signaling Protein

(2009) Alexandra K. Gardino et al.   CELL

Millisecond dynamics in the allosteric enzyme imidazole glycerol phosphate synthase (IGPS) from Thermotoga maritima

(2009) James Lipchock et al.   JOURNAL OF BIOMOLECULAR NMR

Conformational Cycle of the ABC Transporter MsbA in Liposomes: Detailed Analysis Using Double Electron–Electron Resonance Spectroscopy

(2009) Ping Zou et al.   JOURNAL OF MOLECULAR BIOLOGY

Dynamic activation of an allosteric regulatory protein

(2009) Shiou-Ru Tzeng et al.   NATURE

The role of dynamic conformational ensembles in biomolecular recognition

(2009) David D Boehr et al.   Nature Chemical Biology

Ligand-induced global transitions in the catalytic domain of protein kinase A

(2009) C. Hyeon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

mRNA Decapping Is Promoted by an RNA-Binding Channel in Dcp2

(2008) Mandar V. Deshmukh et al.   MOLECULAR CELL

Structural Basis of Dcp2 Recognition and Activation by Dcp1

(2008) Meipei She et al.   MOLECULAR CELL

Internal dynamics control activation and activity of the autoinhibited Vav DH domain

(2008) Pilong Li et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY