GluN2B subunit deletion reveals key role in acute and chronic ethanol sensitivity of glutamate synapses in bed nucleus of the stria terminalis

NR2B-deficient mice are more sensitive to the locomotor stimulant and depressant effects of ethanol

(2011) K. A. Badanich et al.   GENES BRAIN AND BEHAVIOR

Mechanisms underlying NMDA receptor synaptic/extrasynaptic distribution and function

(2011) Clare M. Gladding et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Functional Adaptation of the N-Methyl-D-aspartate Receptor to Inhibition by Ethanol Is Modulated by Striatal-Enriched Protein Tyrosine Phosphatase and p38 Mitogen-Activated Protein Kinase

(2011) P. H. Wu et al.   MOLECULAR PHARMACOLOGY

Stress-induced alterations in anxiety-like behavior and adaptations in plasticity in the bed nucleus of the stria terminalis

(2011) Kelly L. Conrad et al.   PHYSIOLOGY & BEHAVIOR

Alcohol inhibition of the NMDA receptor function, long-term potentiation, and fear learning requires striatal-enriched protein tyrosine phosphatase

(2011) T. R. Hicklin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Loss of GluN2B-Containing NMDA Receptors in CA1 Hippocampus and Cortex Impairs Long-Term Depression, Reduces Dendritic Spine Density, and Disrupts Learning

(2010) J. L. Brigman et al.   JOURNAL OF NEUROSCIENCE

Activation of Extrasynaptic, But Not Synaptic, NMDA Receptors Modifies Amyloid Precursor Protein Expression Pattern and Increases Amyloid-  Production

(2010) K. Bordji et al.   JOURNAL OF NEUROSCIENCE

Memantine Preferentially Blocks Extrasynaptic over Synaptic NMDA Receptor Currents in Hippocampal Autapses

(2010) P. Xia et al.   JOURNAL OF NEUROSCIENCE

Ventral Tegmental Afferents in Stress-Induced Reinstatement: The Role of cAMP Response Element-Binding Protein

(2010) L. A. Briand et al.   JOURNAL OF NEUROSCIENCE

In Vivo Chronic Intermittent Ethanol Exposure Reverses the Polarity of Synaptic Plasticity in the Nucleus Accumbens Shell

(2010) Z. M. Jeanes et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders

(2010) Giles E. Hardingham et al.   NATURE REVIEWS NEUROSCIENCE

Early Increase in Extrasynaptic NMDA Receptor Signaling and Expression Contributes to Phenotype Onset in Huntington's Disease Mice

(2010) Austen J. Milnerwood et al.   NEURON

Glutamate Receptor Ion Channels: Structure, Regulation, and Function

(2010) S. F. Traynelis et al.   PHARMACOLOGICAL REVIEWS

Inactivation of the bed nucleus of the stria terminalis in an animal model of relapse: effects on conditioned cue-induced reinstatement and its enhancement by yohimbine

(2010) Deanne M. Buffalari et al.   PSYCHOPHARMACOLOGY

Protracted Withdrawal from Alcohol and Drugs of Abuse Impairs Long-Term Potentiation of Intrinsic Excitability in the Juxtacapsular Bed Nucleus of the Stria Terminalis

(2009) W. Francesconi et al.   JOURNAL OF NEUROSCIENCE

NMDA Receptor GluN2B (GluR 2/NR2B) Subunit Is Crucial for Channel Function, Postsynaptic Macromolecular Organization, and Actin Cytoskeleton at Hippocampal CA3 Synapses

(2009) K. Akashi et al.   JOURNAL OF NEUROSCIENCE

Phosphorylation Regulates Removal of Synaptic N-Methyl-D-Aspartate Receptors after Withdrawal from Chronic Ethanol Exposure

(2009) P. Clapp et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Predicting new molecular targets for known drugs

(2009) Michael J. Keiser et al.   NATURE

Balance between synaptic versus extrasynaptic NMDA receptor activity influences inclusions and neurotoxicity of mutant huntingtin

(2009) Shu-ichi Okamoto et al.   NATURE MEDICINE

Alcohol Exposure Alters NMDAR Function in the Bed Nucleus of the Stria Terminalis

(2009) Thomas L Kash et al.   NEUROPSYCHOPHARMACOLOGY

Acute Alcohol Action and Desensitization of Ligand-Gated Ion Channels

(2009) A. M. Dopico et al.   PHARMACOLOGICAL REVIEWS

Chronic ethanol exposure leads to divergent control of dopaminergic synapses in distinct target regions

(2008) Julie C. Healey et al.   ALCOHOL

Neuronal viability is controlled by a functional relation between synaptic and extrasynaptic NMDA receptors

(2008) F. Léveillé et al.   FASEB JOURNAL

NMDA Receptor Antagonists Reveal Age-Dependent Differences in the Properties of Visual Cortical Plasticity

(2008) Jacqueline de Marchena et al.   JOURNAL OF NEUROPHYSIOLOGY

Contribution of Hippocampal and Extra-Hippocampal NR2B-Containing NMDA Receptors to Performance on Spatial Learning Tasks

(2008) Jakob von Engelhardt et al.   NEURON