Genomic dissection of the epidermal growth factor receptor (EGFR)/PI3K pathway reveals frequent deletion of the EGFR phosphatase PTPRS in head and neck cancers

Studies of genomic copy number changes in human cancers reveal signatures of DNA replication stress

(2011) Aygül Dereli-Öz et al.   Molecular Oncology

Evaluation of EGFR gene copy number as a predictive biomarker for the efficacy of cetuximab in combination with chemotherapy in the first-line treatment of recurrent and/or metastatic squamous cell carcinoma of the head and neck: EXTREME study

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Epidermal Growth Factor Receptor and K-RAS status in two cohorts of squamous cell carcinomas

(2010) Nancy Van Damme et al.   BMC CANCER

Genomic and Biological Characterization of Exon 4 KRAS Mutations in Human Cancer

(2010) M. Janakiraman et al.   CANCER RESEARCH

The landscape of somatic copy-number alteration across human cancers

(2010) Rameen Beroukhim et al.   NATURE

Regulation of Heparin-Binding EGF-Like Growth Factor by miR-212 and Acquired Cetuximab-Resistance in Head and Neck Squamous Cell Carcinoma

(2010) Hiromitsu Hatakeyama et al.   PLoS One

Nuclear Receptor-Induced Chromosomal Proximity and DNA Breaks Underlie Specific Translocations in Cancer

(2009) Chunru Lin et al.   CELL

An integrated genomic analysis of lung cancer reveals loss of DUSP4 in EGFR-mutant tumors

(2009) D Chitale et al.   ONCOGENE

Prognostic Significance of Epidermal Growth Factor Receptor Phosphorylation and Mutation in Head and Neck Squamous Cell Carcinoma

(2009) T. Hama et al.   ONCOLOGIST

Expression and mutation analysis of epidermal growth factor receptor in head and neck squamous cell carcinoma

(2008) Mahmoud A.L. Sheikh Ali et al.   CANCER SCIENCE

Activation of the PI3-K/AKT pathway and implications for radioresistance mechanisms in head and neck cancer

(2008) Johan Bussink et al.   LANCET ONCOLOGY

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2008) Roger McLendon et al.   NATURE

Platinum-Based Chemotherapy plus Cetuximab in Head and Neck Cancer

(2008) Jan B. Vermorken et al.   NEW ENGLAND JOURNAL OF MEDICINE

PI3K pathway alterations in cancer: variations on a theme

(2008) T L Yuan et al.   ONCOGENE

Functional Copy-Number Alterations in Cancer

(2008) Barry S. Taylor et al.   PLoS One

An Integrated Genomic Analysis of Human Glioblastoma Multiforme

(2008) D. W. Parsons et al.   SCIENCE