Inhibition of helicase activity by a small molecule impairs Werner syndrome helicase (WRN) function in the cellular response to DNA damage or replication stress

Helicases as Prospective Targets for Anti-Cancer Therapy

(2012) Rigu Gupta et al.   Anti-Cancer Agents in Medicinal Chemistry

The RecQ helicase WRN is required for normal replication fork progression after DNA damage or replication fork arrest

(2010) Julia M. Sidorova et al.   CELL CYCLE

Hitting the bull's eye: Novel directed cancer therapy through helicase-targeted synthetic lethality

(2009) Monika Aggarwal et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Inhibition of Poly(ADP-Ribose) Polymerase in Tumors fromBRCAMutation Carriers

(2009) Peter C. Fong et al.   NEW ENGLAND JOURNAL OF MEDICINE

The G-Quadruplex Ligand Telomestatin Impairs Binding of Topoisomerase IIIα to G-Quadruplex-Forming Oligonucleotides and Uncaps Telomeres in ALT Cells

(2009) Nassima Temime-Smaali et al.   PLoS One

Amplifying tumour-specific replication lesions by DNA repair inhibitors – A new era in targeted cancer therapy

(2008) Thomas Helleday   EUROPEAN JOURNAL OF CANCER