Hepatocyte growth factor (HGF) autocrine activation predicts sensitivity to MET inhibition in glioblastoma

A phase II study evaluating the efficacy and safety of AMG 102 (rilotumumab) in patients with recurrent glioblastoma

(2011) P. Y. Wen et al.   NEURO-ONCOLOGY

Exciting New Advances in Neuro-Oncology: The Avenue to a Cure for Malignant Glioma

(2010) E. G. Van Meir et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Preexistence and Clonal Selection of MET Amplification in EGFR Mutant NSCLC

(2010) Alexa B. Turke et al.   CANCER CELL

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

MET Kinase Inhibitor SGX523 Synergizes with Epidermal Growth Factor Receptor Inhibitor Erlotinib in a Hepatocyte Growth Factor-Dependent Fashion to Suppress Carcinoma Growth

(2010) Y.-W. Zhang et al.   CANCER RESEARCH

American Society of Clinical Oncology 2010: report of selected studies from the CNS tumors section

(2010) Patrick Y Wen   Expert Review of Anticancer Therapy

Novel Therapeutic Inhibitors of the c-Met Signaling Pathway in Cancer

(2009) J. P. Eder et al.   CLINICAL CANCER RESEARCH

Hepatocyte growth factor in cerebrospinal fluid is associated with mortality and recurrence of glioblastoma, and could be of prognostic value

(2009) Roberto Garcia-Navarrete et al.   JOURNAL OF NEURO-ONCOLOGY

EGFRvIII and c-Met pathway inhibitors synergize against PTEN-null/EGFRvIII+ glioblastoma xenografts

(2009) B. Lal et al.   MOLECULAR CANCER THERAPEUTICS

SGX523 is an exquisitely selective, ATP-competitive inhibitor of the MET receptor tyrosine kinase with antitumor activity in vivo

(2009) S. G. Buchanan et al.   MOLECULAR CANCER THERAPEUTICS

Showering c-MET-dependent cancers with drugs

(2008) Beatrice S. Knudsen et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

A highly invasive human glioblastoma pre-clinical model for testing therapeutics

(2008) Qian Xie et al.   Journal of Translational Medicine

Transcription-Dependent Epidermal Growth Factor Receptor Activation by Hepatocyte Growth Factor

(2008) T. E. Reznik et al.   MOLECULAR CANCER RESEARCH

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2008) Roger McLendon et al.   NATURE