Article
Chemistry, Multidisciplinary
Honglei Kang, Xudong Jiang, Zhiwei Liu, Fan Liu, Guoping Yan, Feng Li
Summary: Biodegradable scaffolds based on biomedical polymeric materials were prepared using composite materials of PTMC/PLA/HA and PTMC/HA, showing low toxicity, good biodegradability, and biocompatibility while enhancing the cell multiplication ability of osteoblast cells.
Article
Engineering, Biomedical
Xiaohu Chen, Zuoxun Huang, Qing Yang, Xiyang Zeng, Ruqing Bai, Li Wang
Summary: This study developed a biodegradable composite porous polyurethane scaffold with responsive shape changing performance and good osteoconductivity, making it a promising candidate for implantation of bone defects.
BIOMEDICAL MATERIALS
(2022)
Article
Polymer Science
Leonard Bauer, Anamarija Rogina, Marica Ivankovic, Hrvoje Ivankovic
Summary: The production of biocompatible composite scaffolds using additive manufacturing is growing in popularity. This study focuses on the effects of different grades of polymers and the addition of hydroxyapatite (HAp) on the degradation behavior and thermal stability of the scaffolds. The results show that a higher HAp content slows down the degradation of the polymer and improves its thermal stability, as evidenced by morphological changes and differences in glass transition temperatures throughout the samples.
Article
Polymer Science
Nonni Soraya Sambudi, Wai Yi Lin, Noorfidza Yub Harun, Dhani Mutiari
Summary: Traditional fossil-based plastic usage and disposal pose significant environmental concerns. Poly(lactic acid) (PLA) has gained attention as a safer alternative due to its renewable nature and low environmental cost. This study explores the potential use of orange peel waste in enhancing the PLA matrix. The addition of orange peel fine powder (OPP) improves the biodegradability of PLA and enhances its absorption in alkaline solution.
Article
Engineering, Mechanical
Gaurav Tripathi, Pulak Mohan Pandey
Summary: This work focuses on the fabrication of biodegradable iron-hydroxyapatite (Fe-HAp) composite using rapid tooling and pressureless microwave sintering. The effect of process parameters on the properties of the composite was evaluated using response surface methodology and the most influential parameter was found to be the HAp percentage. The proper bonding of particles without any pressure application and the absence of oxidation and contamination from the mold material were confirmed through scanning electron microscopy and X-ray diffraction analysis.
PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART C-JOURNAL OF MECHANICAL ENGINEERING SCIENCE
(2023)
Article
Chemistry, Physical
Yen-Han Lai, Yung-Hsin Chen, Arnab Pal, Syun-Hong Chou, Shwu-Jen Chang, E-Wen Huang, Zong-Hong Lin, San-Yuan Chen
Summary: A degradable piezoelectric scaffold was developed to modulate cell behavior and differentiation, promoting chondrocyte differentiation and enhancing extracellular matrix secretion. Dynamic mechanical loading and electrical stimulation of the scaffold significantly improved cell functions and ECM synthesis.
Article
Materials Science, Multidisciplinary
Beh Chong You, Cheng Ee Meng, Nashrul Fazli Mohd Nasir, Emma Ziezie Mohd Tarmizi, Khor Shing Fhan, Eng Swee Kheng, Mohd Shukry Abdul Majid, Mohd Ridzuan Mohd Jamir
Summary: This study investigates the dielectric properties and biodegradation properties of nano-hydroxyapatite/starch bone scaffold. The dielectric properties of the scaffold decrease with increasing frequency, but increase with starch proportion and temperature. Improved dielectric properties and porosity enhance the biodegradation properties of the scaffold. The scaffold with a high starch proportion exhibits strong intermolecular interactions and stable biodegradation and biomineralization. The dielectric properties of the simulated body solutions are sensitive to ion concentrations.
JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T
(2022)
Article
Materials Science, Multidisciplinary
Ahmad Saudi, Seyed Mojtaba Zebarjad, Hossein Salehi, Elham Katoueizadeh, Aliakbar Alizadeh
Summary: The study examined the morphology, surface contact angle, mechanical properties, in vitro degradation behavior, and water uptake of PCL/PGS/HAp fibers, showing that HAp particles have a positive effect on PC12 viability and adhesion.
MATERIALS CHEMISTRY AND PHYSICS
(2022)
Article
Engineering, Biomedical
Rakesh Kumar, Anupam Agrawal
Summary: Biomaterials with higher strength and increased bioactivity are being widely researched for scaffold and implant fabrication. Metal-based biomaterials are ideal for load-bearing implants due to their impressive mechanical and structural properties. However, the mismatch between the mechanical properties of the human body and the pure metallic implant can cause damage. This study aims to combine a biocompatible ceramic with metal to lower the overall mechanical strength and enhance the composite's bioactivity. The fabricated Ti-mu-HAp composites show a decreasing trend in nano-mechanical and micro-hardness properties, confirming their ability to minimize stress-shielding impact.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2023)
Article
Polymer Science
Yejin Park, Jonghwi Lee
Summary: A PLA/FP composite foam was prepared by infiltrating PLA solution into a cellulose foam formed by melt crystallization method. The composite foam showed improved mechanical properties and thermal stability, and has potential applications as insulation and cushioning materials.
Article
Materials Science, Multidisciplinary
Pei Feng, Jiye Jia, Li Yu, Anjie Min, Sheng Yang, Cijun Shuai
Summary: The addition of L-LA into PLLA scaffold promoted its degradation rate by weakening intermolecular forces and introducing hydrophilic functional groups, leading to reduced crystallinity and increased weight loss. The scaffold also exhibited good cytocompatibility for cell adhesion and growth with enhanced cell numbers and adhesion area over time.
MATERIALS CHEMISTRY AND PHYSICS
(2021)
Article
Chemistry, Multidisciplinary
Rong Wang, Xiaojie Sun, Lanlan Chen, Wenbin Liang
Summary: In this study, biodegradable blends of PGA and PBAT with in situ compatibilization using MDI were prepared. The addition of PBAT was found to increase the complex viscosity and storage modulus of the blends, leading to improved compatibility and impact strength. The morphology of the dispersed phase evolved from spherical structure to in situ microfiber, enhancing interfacial adhesion and improving toughness.
Article
Materials Science, Multidisciplinary
Jie Meng, Francesco Boschetto, Shinichi Yagi, Elia Marin, Tetsuya Adachi, Xuefei Chen, Giuseppe Pezzotti, Shinichi Sakurai, Hideki Yamane, Huaizhong Xu
Summary: This study successfully prints the thermally sensitive polymer PLLA to a high-resolution object using the melt electrowriting technology, and manufactures PLLA scaffolds with adjustable filament diameter and pore size for bone tissue engineering. By investigating the relationships among the rheological behavior, electro-hydrodynamics, and processing parameters, relatively high deposition accuracy and crystallinity of PLLA were achieved. The PLLA scaffold with filament diameter of 40 μm and pore size of 200 μm was evaluated with cells to demonstrate its in vitro potential, marking a milestone for melt electrowriting in designing and manufacturing essential biobased polymers for tissue engineering.
MATERIALS & DESIGN
(2021)
Review
Polymer Science
Maria Laura Di Lorenzo
Summary: PLLA and PBS are biodegradable, compostable, and biocompatible polymers that have complementary properties, making blending them an opportunity to exploit their favorable characteristics. However, research on the properties of PLLA/PBS blends has yielded contradictory results, creating complexity in their utilization.
Article
Chemistry, Physical
Seung-Woon Baek, Duck Hyun Song, Ho In Lee, Da-Seul Kim, Yun Heo, Jun Hyuk Kim, Chun Gwon Park, Dong Keun Han
Summary: The study improved the mechanical and biological properties of PLLA/MH composites by grafting OLCL onto MH, reducing platelet adhesion, cytotoxicity, and inflammatory responses. This offers a new approach for the application of biomedical materials.