标题
Targeting Mdmx to treat breast cancers with wild-type p53
作者
关键词
-
出版物
Cell Death & Disease
Volume 6, Issue 7, Pages e1821-e1821
出版商
Springer Nature
发表日期
2015-07-16
DOI
10.1038/cddis.2015.173
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Alterations in gene expression and sensitivity to genotoxic stress following HdmX or Hdm2 knockdown in human tumor cells harboring wild-type p53
- (2016) Katherine Heminger et al. Aging-US
- Role of p53 in the progression of gastric cancer
- (2015) Rita A. Busuttil et al. Oncotarget
- Amplification of Mdmx and overexpression of MDM2 contribute to mammary carcinogenesis by substituting for p53 mutations
- (2014) Qiong Yu et al. Diagnostic Pathology
- Wild type p53 reactivation: From lab bench to clinic
- (2014) Galina Selivanova FEBS LETTERS
- Drugging the p53 pathway: understanding the route to clinical efficacy
- (2014) Kian Hoe Khoo et al. NATURE REVIEWS DRUG DISCOVERY
- Cellular senescence: from physiology to pathology
- (2014) Daniel Muñoz-Espín et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- p53 in breast cancer subtypes and new insights into response to chemotherapy
- (2013) Philippe Bertheau et al. BREAST
- Targeting BCL-2 with the BH3 Mimetic ABT-199 in Estrogen Receptor-Positive Breast Cancer
- (2013) François Vaillant et al. CANCER CELL
- The rebel angel: mutant p53 as the driving oncogene in breast cancer
- (2012) D. Walerych et al. CARCINOGENESIS
- Distincttumor protein p53mutants in breast cancer subgroups
- (2012) Anne Dumay et al. INTERNATIONAL JOURNAL OF CANCER
- The molecular characterisation of unusual subcutaneous spindle cell lesion of breast
- (2012) Elena A Takano et al. JOURNAL OF CLINICAL PATHOLOGY
- Effect of the MDM2 antagonist RG7112 on the P53 pathway in patients with MDM2-amplified, well-differentiated or dedifferentiated liposarcoma: an exploratory proof-of-mechanism study
- (2012) Isabelle Ray-Coquard et al. LANCET ONCOLOGY
- MDM4 is a key therapeutic target in cutaneous melanoma
- (2012) Agnieszka Gembarska et al. NATURE MEDICINE
- Activation of the p53 pathway by small-molecule-induced MDM2 and MDMX dimerization
- (2012) B. Graves et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Ink4-Arf locus in cancer and aging
- (2012) Charles J. Sherr Wiley Interdisciplinary Reviews-Developmental Biology
- Validation of MdmX as a therapeutic target for reactivating p53 in tumors
- (2011) D. Garcia et al. GENES & DEVELOPMENT
- The Human Protein Atlas as a proteomic resource for biomarker discovery
- (2011) F. Pontén et al. JOURNAL OF INTERNAL MEDICINE
- Pharmacological Rescue of p53 in Cancer Therapy: Widening the Sensitive Tumor Spectrum by Targeting MDMX
- (2010) Jean-Christophe Marine CANCER CELL
- Comprehensive Mapping of p53 Pathway Alterations Reveals an Apparent Role for Both SNP309 and MDM2 Amplification in Sarcomagenesis
- (2010) M. Ito et al. CLINICAL CANCER RESEARCH
- A Small-Molecule Inhibitor of MDMX Activates p53 and Induces Apoptosis
- (2010) H. Wang et al. MOLECULAR CANCER THERAPEUTICS
- Role of Mdm4 in drug sensitivity of breast cancer cells
- (2010) S Lam et al. ONCOGENE
- Promyelocytic Leukemia Protein is Required for Gain of Function by Mutant p53
- (2009) S. Haupt et al. CANCER RESEARCH
- A polymorphic variant in human MDM4 associates with accelerated age of onset of estrogen receptor negative breast cancer
- (2009) Diptee A. Kulkarni et al. CARCINOGENESIS
- Ki67 Index, HER2 Status, and Prognosis of Patients With Luminal B Breast Cancer
- (2009) Maggie C. U. Cheang et al. JNCI-Journal of the National Cancer Institute
- Mutation analysis of the MDM4gene in German breast cancer patients
- (2008) Scarlett Reincke et al. BMC CANCER
- Inducible and reversible gene silencing by stable integration of an shRNA-encoding lentivirus in transgenic rats
- (2008) M. J. Herold et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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