The P’s and Q’s of cellular PrP-Aβ interactions

Neuronal receptors as targets for the action of amyloid-beta protein (Aβ) in the brain

(2012) Aarti N. Patel et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes

(2012) Iryna Benilova et al.   NATURE NEUROSCIENCE

Trans-Synaptic Spread of Tau Pathology In Vivo

(2012) Li Liu et al.   PLoS One

A  neurotoxicity depends on interactions between copper ions, prion protein, and N-methyl-D-aspartate receptors

(2012) H. You et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PrP Antibodies Do Not Trigger Mouse Hippocampal Neuron Apoptosis

(2012) P.-C. Klohn et al.   SCIENCE

Actions of β-Amyloid Protein on Human Neurons Are Expressed through the Amylin Receptor

(2011) Jack H. Jhamandas et al.   AMERICAN JOURNAL OF PATHOLOGY

The cellular prion protein mediates neurotoxic signalling of β-sheet-rich conformers independent of prion replication

(2011) Ulrike K Resenberger et al.   EMBO JOURNAL

Prion Protein Interacts with BACE1 Protein and Differentially Regulates Its Activity toward Wild Type and Swedish Mutant Amyloid Precursor Protein

(2011) Heledd H. Griffiths et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

α-Secretase-derived Fragment of Cellular Prion, N1, Protects against Monomeric and Oligomeric Amyloid β (Aβ)-associated Cell Death

(2011) Marie-Victoire Guillot-Sestier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amyloid-β-induced Synapse Damage Is Mediated via Cross-linkage of Cellular Prion Proteins

(2011) Clive Bate et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Naturally Occurring C-terminal Fragment of the Prion Protein (PrP) Delays Disease and Acts as a Dominant-negative Inhibitor of PrPScFormation

(2011) Laura Westergard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A  Inhibition of Ionic Conductance in Mouse Basal Forebrain Neurons Is Dependent upon the Cellular Prion Protein PrPC

(2011) K. Alier et al.   JOURNAL OF NEUROSCIENCE

Alzheimer's Disease Brain-Derived Amyloid- -Mediated Inhibition of LTP In Vivo Is Prevented by Immunotargeting Cellular Prion Protein

(2011) A. E. Barry et al.   JOURNAL OF NEUROSCIENCE

Ablation of Cellular Prion Protein Does Not Ameliorate Abnormal Neural Network Activity or Cognitive Dysfunction in the J20 Line of Human Amyloid Precursor Protein Transgenic Mice

(2011) M. Cisse et al.   JOURNAL OF NEUROSCIENCE

Prion protein at the crossroads of physiology and disease

(2011) Emiliano Biasini et al.   TRENDS IN NEUROSCIENCES

Interaction between prion protein and toxic amyloid β assemblies can be therapeutically targeted at multiple sites

(2011) Darragh B. Freir et al.   Nature Communications

Prion protein and Aβ-related synaptic toxicity impairment

(2010) Anna Maria Calella et al.   EMBO Molecular Medicine

Interaction between Human Prion Protein and Amyloid-β (Aβ) Oligomers

(2010) Shugui Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Memory Impairment in Transgenic Alzheimer Mice Requires Cellular Prion Protein

(2010) D. A. Gimbel et al.   JOURNAL OF NEUROSCIENCE

Ionic mechanisms of action of prion protein fragment PrP(106-126) in rat basal forebrain neurons

(2010) Kwai Alier et al.   JOURNAL OF NEUROSCIENCE RESEARCH

The prion protein as a receptor for amyloid-β

(2010) Helmut W. Kessels et al.   NATURE

Axonal prion protein is required for peripheral myelin maintenance

(2010) Juliane Bremer et al.   NATURE NEUROSCIENCE

Synthetic amyloid-  oligomers impair long-term memory independently of cellular prion protein

(2010) C. Balducci et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of ADAMs in the Ectodomain Shedding and Conformational Conversion of the Prion Protein

(2009) David R. Taylor et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The α-Secretase-derived N-terminal Product of Cellular Prion, N1, Displays Neuroprotective Functionin Vitroandin Vivo

(2009) Marie-Victoire Guillot-Sestier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Propagation of Tau Misfolding from the Outside to the Inside of a Cell

(2009) Bess Frost et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cellular prion protein mediates impairment of synaptic plasticity by amyloid-β oligomers

(2009) Juha Laurén et al.   NATURE

Influence of ADAM10 on prion protein processing and scrapie infectiosity in vivo

(2009) Kristina Endres et al.   NEUROBIOLOGY OF DISEASE

The Transcellular Spread of Cytosolic Amyloids, Prions, and Prionoids

(2009) Adriano Aguzzi et al.   NEURON

Exogenous  -synuclein fibrils seed the formation of Lewy body-like intracellular inclusions in cultured cells

(2009) K. C. Luk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interactome Analyses Identify Ties of PrPC and Its Mammalian Paralogs to Oligomannosidic N-Glycans and Endoplasmic Reticulum-Derived Chaperones

(2009) Joel C. Watts et al.   PLoS Pathogens

The Prion's Elusive Reason for Being

(2008) Adriano Aguzzi et al.   Annual Review of Neuroscience

Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation

(2008) Jia-Yi Li et al.   NATURE MEDICINE

Physiology of the Prion Protein

(2008) Rafael Linden et al.   PHYSIOLOGICAL REVIEWS