Article
Chemistry, Multidisciplinary
Zhenhua Liang, Kangwei Zheng, Qingchun Zhao, Wenjing Shao, Changqin Li, Jinmei Wang, Changyang Ma, Wenyi Kang
Summary: Two polysaccharides, CHFVP-1 and CHFVP-2, were successfully isolated from Flammulina velutipes and their structures were determined. CHFVP-1 exhibited procoagulant activity, while CHFVP-2 did not show significant coagulant activity. This finding could contribute to the further utilization of Flammulina velutipes in the field of medicine.
APPLIED SCIENCES-BASEL
(2021)
Article
Biochemistry & Molecular Biology
Yuting Hao, Xiangdong Wang, Sijie Yuan, Yingyi Wang, Xiaoshan Liao, Meiling Zhong, Qiangnan He, Haibin Shen, Wenzhen Liao, Jie Shen
Summary: Flammulina velutipes polysaccharides (FVP) have the potential to improve gut health by regulating gut microbiota and metabolism. The study reveals changes in intestinal tissue structure, microbiota composition, and metabolic profiling induced by FVP treatment, suggesting it as a promising dietary supplement for promoting intestinal health.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Nutrition & Dietetics
Sheng Ma, Jianxiong Xu, Ting Lai, Weina Xu, Jing Zhang, Hongcai Zhang, Weiyi Zhang
Summary: This study investigated the antioxidant and anti-inflammatory capacities of Flammulina velutipes polysaccharides (FVPs) and fermented FVP (FFVP) on mice intestinal inflammation. The results showed that FFVP had higher antioxidant and anti-inflammatory activities than FVP, indicating its potential application in functional food and health products. Inhibition of the NLRP3 signaling pathway activation may be one of the anti-inflammatory mechanisms of FVP and FFVP.
FRONTIERS IN NUTRITION
(2022)
Article
Biochemistry & Molecular Biology
Xue Shao, Ben Niu, Xiangjun Fang, Weijie Wu, Ruiling Liu, Honglei Mu, Haiyan Gao, Hangjun Chen
Summary: In this study, cinnamaldehyde emulsion was prepared using soybean phospholipids and pullulan. The emulsion coating showed a positive effect on inhibiting reactive oxygen species accumulation and improving the delaying effectiveness of free radical scavenging enzymes. It also significantly prolonged the shelf life of mushrooms, indicating its potential application in food preservation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biotechnology & Applied Microbiology
Yufan Zhu, Feixiang Chen, Minhao Wu, Jieyu Xiang, Feifei Yan, Yuanlong Xie, Zan Tong, Yun Chen, Lin Cai
Summary: In this study, a novel HFV cryogel was successfully constructed and showed promising potential in wound healing. The HFV70 cryogel exhibited a loose porous structure with desirable properties such as high porosity and water uptake ratio. In vitro and in vivo experiments demonstrated that HFV70 had improved cytocompatibility, hemocompatibility, antibacterial, and antioxidant properties. It also showed rapid and effective hemostasis and promoted tissue regeneration in a rat model. Overall, HFV70 has great importance in the treatment of full-thickness skin defects and achieving rapid hemostasis.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Review
Biochemistry & Molecular Biology
Yongxia Wang, Hua Zhang
Summary: This paper reviews the extraction, purification, structural characteristics, and bioactivities of Flammulina velutipes polysaccharides (FVPs), as well as discusses the structural-property relationships. The possible mechanisms of bioactivities were summarized based on in vitro and in vivo experiments, along with the current application status and future research directions of FVPs. The research aims to provide a reference for the further development of FVPs.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Food Science & Technology
Ying Ding, Sitan Chen, Honglin Wang, Shanlei Li, Changyang Ma, Jinmei Wang, Lili Cui
Summary: In this study, secondary metabolites of Flammulina velutipes were identified using advanced technology, resulting in the identification of 26 secondary metabolites including flavonoids, phenylpropanoids, organic acids, and steroids.
JOURNAL OF FOOD QUALITY
(2021)
Article
Biochemistry & Molecular Biology
Feixiang Chen, Qiang Zhang, Ping Wu, Yanan Zhao, Xiaotong Suo, Ao Xiao, Meifang Ke, Xiaohua He, Zan Tong, Yun Chen
Summary: A novel seedbed-like scaffold fabricated using Flammulina velutipes showed excellent biological activity and water absorption capacity after further optimization processing. The Flammulina velutipes polysaccharides-derived scaffolds exhibited remarkable antibacterial activity against various bacteria and promoted accelerated wound healing and hair follicle regeneration in a rat skin wound model.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Neurosciences
Lisa Wintzell, Samuel Klemetz, Stefan Lange, Eric Hanse, Caroline Wass, Joakim Strandberg
Summary: The endogenous peptide antisecretory factor (AF) enhances long-term potentiation (LTP) and spatial learning and memory by disinhibiting GABAergic transmission in the rat hippocampus.
Article
Behavioral Sciences
Amanda Dyer, Maxine De Butte
Summary: This study aimed to examine the effects of chronic low-dose vanadium administration on the behavior of young male rats. The findings suggest that vanadium does not significantly affect exploration, locomotion, or anxiety-like behavior in rats, but does affect novel object recognition performance. Additionally, vanadium administration led to lower latency times in the Morris Water maze task.
BEHAVIOURAL BRAIN RESEARCH
(2022)
Article
Nutrition & Dietetics
Liang Ling, Ying Liu, Xin Zhang, Tariq Aziz, Muhammad Shahzad, Manal Y. Sameeh, Ying Wang, Chunbo Cai, Yingchun Zhu
Summary: This study found that Flammulina velutipes polysaccharides (FVPs) have a good protective effect on catfish surimi during frozen storage, reducing protein oxidation and improving physicochemical properties, as well as enhancing the gel structure of the surimi.
FRONTIERS IN NUTRITION
(2023)
Article
Food Science & Technology
Miao Ding, Kai Lv, Dongliang Zhang, Wentao Fan, Ivan Steve Nguepi Tsopmejio, Zhouyu Jin, Hui Song
Summary: This study demonstrates that FVP induces ERS-mediated apoptosis in HepG2 cells by activating the PLC-IP3 pathway. This work may suggest that FVP could be used as an adjuvant therapy to anticancer drugs, providing new application prospects and possibilities.
JOURNAL OF FOOD SCIENCE
(2023)
Article
Behavioral Sciences
Ewa Zwierzynska, Boguslawa Pietrzak
Summary: Lacosamide does not impair memory and learning processes, with temporary disruption of emotional memory observed only after a single high dose administration.
EPILEPSY & BEHAVIOR
(2021)
Article
Medicine, Research & Experimental
Fateme Khodabande, Esmaeil Akbari, Motahareh Rouhi Ardeshiri
Summary: The orexin 1 receptors in the dorsal raphe nucleus play a significant role in the consolidation of spatial reference memory in rats, while the orexin 2 receptors do not have an effect.
Article
Neurosciences
Keyvan Mehri, Zohreh Zavvari Oskuye, Ehsan Nassireslami, Esmail Karami, Mohammad Reza Parvizi
Summary: This study investigated the effects of Botulinum toxin on spatial memory and biochemical and histological parameters in the hippocampus of male rats. Results showed that Botox significantly impaired memory performance and led to a decrease in acetylcholine levels, increase in acetylcholinesterase activity, and morphological damage in the hippocampus. Administration of Rivastigmine partially alleviated these effects and could serve as a protective approach.
