Article
Agriculture, Dairy & Animal Science
K. Fries-Craft, S. Schmitz-Esser, E. A. Bobeck
Summary: This study developed peptide-specific anti-IL-4 antibodies and evaluated immune cell profiles and the cecal microbiota during Eimeria challenge. The anti-IL-4 did not alter baseline performance but increased the number of PBMC B cells. Eimeria challenge reduced feed intake and body weight gain, and the effects of anti-IL-4 were likely host-specific.
Article
Agriculture, Dairy & Animal Science
A. O. Sokale, C. J. Williams, F. J. Hoerr, K. E. C. Collins, E. D. Peebles
Summary: The age and type of injection can impact the growth performance of broiler chickens and the level of coccidia, affecting growth in the early stages but potentially leading to compensatory growth later on.
Article
Agriculture, Dairy & Animal Science
R. P. Snyder, M. T. Guerin, B. M. Hargis, G. Page, J. R. Barta
Summary: This study sampled commercial Ontario broiler chicken flocks to determine differences in oocyst shedding patterns between medicated flocks and vaccinated flocks. Despite higher oocyst shedding in medicated flocks, their performance data were similar to vaccinated flocks.
Article
Parasitology
Jordan Eckert, Miranda Carrisosa, Ruediger Hauck
Summary: The study found that broilers vaccinated against coccidia have similar body weight and feed conversion rate at processing age compared to those given anticoccidial drugs, with results slightly favoring the use of drugs. This meta-analysis also confirmed the robustness of the research and highlighted the need for further investigation into under-researched areas and concerns regarding data quality in coccidia research.
VETERINARY PARASITOLOGY
(2021)
Article
Agriculture, Dairy & Animal Science
C. Orso, B. L. Cony, J. P. Silva, J. C. V. Furtado, M. B. Mann, J. Frazzon, A. P. G. Frazzon, I. Andretta, A. M. L. Ribeiro
Summary: This experiment aimed to determine whether adding gelatin and vitamin E to the diet of male Cobb broilers vaccinated for coccidiosis can alleviate impaired performance. The results showed that vaccination negatively affected performance in the first 21 days, but the inclusion of gelatin and vitamin E reduced this negative response and improved performance. Additionally, vaccinated chickens had increased pro-inflammatory immune status and mucin expression compared to broilers receiving salinomycin.
Article
Immunology
Quail Das, Julie Shay, Martin Gauthier, Xianhua Yin, Teri-Lyn Hasted, Kelly Ross, Carl Julien, Hassina Yacini, Yan Martel Kennes, Keith Warriner, Massimo F. Marcone, Moussa S. Diarra
Summary: Feeding practices can impact poultry gut microbiota and immunity, with bacitracin and berry pomaces showing significant effects on gut microbiota and blood metabolites in chickens, potentially influenced by vaccination against coccidiosis.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Agriculture, Dairy & Animal Science
Zhouzheng Ren, Jiakun Yan, Rose Whelan, Xujie Liao, Daniel E. Buetz, Maria K. Arendt, Mark E. Cook, Xiaojun Yang, Thomas D. Crenshaw
Summary: This study found that increasing sulfur amino acids methionine and cysteine in the diet can enhance the intestinal immune defense against Eimeria induced by anti-interleukin-10, reducing the occurrence of infection. The findings underscore the importance of providing sufficient nutrients to support the anti-IL-10 induced immunity against coccidiosis.
Article
Agriculture, Dairy & Animal Science
S. A. Fatemi, K. E. C. Elliott, A. Bello, E. D. Peebles
Summary: The study found that the administration of 25-hydroxyvitamin D-3 (25OHD(3)) solution injection in broilers resulted in increased body weight gain and pectoralis major muscle percentage. Birds in the 25OHD(3) treatment group showed better performance after challenge compared to those receiving commercial diluent injection.
Review
Biochemistry & Molecular Biology
Jingwei Shi, Xujun Song, Benno Traub, Michael Luxenhofer, Marko Kornmann
Summary: IL-4 and IL-13 are pleiotropic Th2 cytokines involved in immune responses and have been found to play a role in oncogenesis and tumor progression. Their effects on tumor cells are mediated through specific receptors, with IL-4R alpha/IL-13R alpha 1 being the main target in tumors. Understanding the implications of these cytokines and their receptors in pancreatic cancer helps in developing potential new diagnostic and therapeutic strategies.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Veterinary Sciences
Desiree S. Jansson, Johan Hoglund, Elisabeth Bagge, Tomas Jinnerot, Magne Kaldhusdal
Summary: In recent years, the number of organic chicken farms has increased. This study aimed to investigate the effectiveness of coccidia vaccination in preventing diseases in organic chickens. The results showed that vaccinated chickens had milder gut lesions, fewer harmful bacteria, and similar or higher body weight compared to unvaccinated chickens. No deaths from coccidiosis or necrotic enteritis occurred among vaccinated chickens. This study provides valuable knowledge for the development of the organic chicken industry and has relevance to the management of these diseases in conventional broilers.
VETERINARY SCIENCES
(2022)
Article
Agriculture, Dairy & Animal Science
Seyed Abolghasem Fatemi, Katie E. C. Elliott, Ken S. Macklin, Abiodun Bello, Edgar David Peebles
Summary: The study evaluated the effects of in ovo administration of vitamin D-3 and 25-hydroxyvitamin D-3 on the inflammatory response and small intestine morphology of broilers challenged with coccidiosis. In ovo injection of 2.4 mu g of 25OHD(3) reduced plasma nitric oxide levels and increased duodenal VCR compared to other treatments at two weeks post-challenge. This suggests that in ovo administration of 2.4 mu g of 25OHD(3) at 18 days of incubation can enhance broiler intestinal histomorphology and decrease inflammatory reactions during coccidiosis challenge.
Review
Biochemistry & Molecular Biology
Xujun Song, Benno Traub, Jingwei Shi, Marko Kornmann
Summary: IL-4 and IL-13 are structurally and functionally related cytokines that regulate immune responses and are involved in the pathogenesis of various human neoplasms. They can mediate tumor cell proliferation, survival, and metastasis in solid tumors through different receptors. This review summarizes their role in gastric and colon cancer.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Veterinary Sciences
Iqra Zaheer, Wei Chen, Ahrar Khan, Abdelmotaleb Elokil, Muhammad Kashif Saleemi, Tean Zaheer, Muhammad Zargham Khan
Summary: This study compares the immunopathological effects of in ovo vaccination and post-hatch vaccination against IBD in White Leghorn chicks. The results show that in ovo vaccinated groups have higher antibody titers and long-term protective immunity against IBD.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Agriculture, Dairy & Animal Science
Yalcin Yaman, Ramazan Aymaz, Murat Keles, Veysel Bay, Mehmet Ozuicli, Bayram Senlik
Summary: The study found genetic associations between TLR4 gene coding variants and the presence of Eimeria spp. in adult Turkish sheep. A specific SNP encoding Leucine instead of Phenylalanine at a particular codon was significantly associated with the presence of Eimeria spp., increasing the risk by 2.3 times for individuals carrying this Leucine amino acid sequence.
ANIMAL BIOTECHNOLOGY
(2021)
Article
Immunology
Valerie C. Marcano, Stivalis Cardenas-Garcia, Diego G. Diel, Luciana H. Antoniassi da Silva, Robert M. Gogal, Patti J. Miller, Corrie C. Brown, Salman Latif Butt, Iryna V. Goraichuk, Kiril M. Dimitrov, Tonya L. Taylor, Dawn Williams-Coplin, Timothy L. Olivier, James B. Stanton, Claudio L. Afonso
Summary: The study investigated the efficacy of in ovo vaccination with a specific vaccine against Newcastle disease in chicken embryos, showing that the vaccine provided effective protection, reduced mortality rates, and generated strong immune response against the challenge virus.
Article
Agriculture, Dairy & Animal Science
Jesper Tessin, Judith Rohde, Arne Jung, Nicole Kemper, Jochen Schulz
Summary: In this study, samples from poultry house environment and culled birds were collected, and E. cecorum was successfully isolated. The principle of isolating the pathogen by streaking on a chromogenic agar may motivate researchers to investigate transmission routes and optimize biosecurity measures.
Article
Agriculture, Dairy & Animal Science
Junqin Zhang, Zimin Xie, Yanlin Pan, Zuoxin Chen, Yunzhen Huang, Linlin Li, Jiawen Dong, Yong Xiang, Qi Zhai, Minhua Sun, Xingying Li, Shujian Huang, Ming Liao
Summary: In recent years, there has been an increase in the occurrence of fowl adenovirus 2 (FAdV-2) in China, posing a significant threat to the poultry industry. This study investigated the epidemiology, phylogenetic relationship, genomic characteristics, and pathogenicity of FAdV-2. The results showed that FAdV-2 was the most commonly detected serotype among various FAdV serotypes. Genetic analysis revealed that these FAdV-2 strains formed a distinct branch within the FAdV-D group and had a high nucleotide similarity with reference strains. Recombination analysis identified recombination events between FAdV-2 and FAdV-11 in some strains. Pathogenicity experiments demonstrated that a recombinant FAdV-2 strain caused a high mortality rate and more severe disease in chickens. These findings contribute to our understanding of FAdV-2 and provide a basis for vaccine development.
Article
Agriculture, Dairy & Animal Science
Ebtsam Iraqi, Ali Abdel Hady, Nadia Elsayed, Hanaa Khalil, Amina El-Saadany, Karim El-Sabrout
Summary: Thermal manipulation during egg incubation, particularly at 12 to 18 days, has positive effects on embryonic development, hatching characteristics, chick quality, as well as posthatch thermotolerance and performance.
Article
Agriculture, Dairy & Animal Science
Yong Liu, Mingxin Song, He Bai, Chunhua Wang, Fei Wang, Qi Yuan
Summary: Dietary curcumin supplementation can significantly improve egg quality of quails in the late laying period, primarily by improving lipid metabolism and selectively regulating the intestinal microbial community.
Article
Agriculture, Dairy & Animal Science
Lei Zhang, Zhixuan Song, Peiyao Li, Xingju Song, Xinming Tang, Dandan Hu
Summary: This study evaluated the vaccine potential of recombinant proteins for avian coccidiosis caused by Eimeria. The results showed that the rEten5-B protein can trigger immune protection against E. tenella and may be a potential and effective subunit vaccine for the control of coccidiosis in poultry.
Article
Agriculture, Dairy & Animal Science
Milan Kumar Sharma, Amit Kumar Singh, Doyun Goo, Venkata Sesha Reddy Choppa, Hanseo Ko, Hanyi Shi, Woo Kyun Kim
Summary: The study investigates the effect of Eimeria infection on gastrointestinal physiology, growth performance, and egg production of Hy-Line W-36 laying hens during peak production. Results show that Eimeria infection negatively affects body weight, feed intake, immune response, and nutrient transporter gene expression. Egg production temporarily ceases in hens infected with high and medium-high dosages of Eimeria.
Article
Agriculture, Dairy & Animal Science
Elwy A. Ashour, Mahmoud Kamal, Hayman A. A. Altaie, Ayman A. Swelum, Gamaleldin M. Suliman, Guillermo Tellez-Isaias, Mohamed E. Abd El-Hack
Summary: This study evaluated the effects of CP and ME on the performance and nutritional value of Japanese quail lay chicken. The results showed that protein and energy levels significantly influenced all productive outcomes except feed conversion ratio. The combination of dietary energy and protein levels had a substantial effect on all egg quality trials evaluated. It is recommended to feed layer Japanese quail between the ages of 8 and 20 weeks during the summer with a dietary energy content of 2,900 kcal ME/kg and 20% CP.
Article
Agriculture, Dairy & Animal Science
J. E. Doornweerd, R. F. Veerkamp, B. de Klerk, M. van der Sluis, A. C. Bouwman, E. D. Ellen, G. Kootstra
Summary: Tracking group-housed individual broilers using video can provide valuable information on their health, welfare, and performance. This study conducted a comprehensive analysis on broiler tracking on video and potential tracking errors, highlighting the potential and challenges of phenotyping broiler locomotion. The results emphasized the importance of addressing tracking errors, potential algorithm improvements, and the need for an external animal identification system for efficient locomotion phenotyping.
Article
Agriculture, Dairy & Animal Science
Jiayu Wu, Yanan Wang, Yu An, Changyu Tian, Lingfeng Wang, Zuhong Liu, Desheng Qi
Summary: This study compared the gene expression differences in liver tissues of laying hens at different ages using RNA sequencing, and found that the transport and metabolism of amino acids changed during the growing period, which influenced the growth and development of the hens.
Article
Agriculture, Dairy & Animal Science
J. Raabe, G. Raveendran, W. Otten, K. Homeyer, T. Bartels
Summary: This study investigated the effects of different flicker frequencies on the behavior, performance, and stress response in male turkeys. The results showed that flicker frequencies of 165 Hz or higher had no detrimental effect on growth performance, injurious pecking, or endocrine stress response in the turkeys.
Article
Agriculture, Dairy & Animal Science
Adamu Mani Isa, Yanyan Sun, Yuanmei Wang, Yunlei Li, Jingwei Yuan, Aixin Ni, Hui Ma, Lei Shi, Hailai Hagos Tesfay, Yunhe Zong, Panlin Wang, Pingzhuang Ge, Jilan Chen
Summary: This study sequenced mRNAs and lncRNAs in the ovary stroma of specific chicken breeds and their reciprocal crossbreds to understand the molecular mechanism of heterosis for egg production. Results showed that genes with nonadditive expression were related to follicle growth and atresia as well as oxidative stress in the crossbred hens.
Article
Agriculture, Dairy & Animal Science
Zhepeng Wang, Qiu Chen, Yiwei Wang, Yulu Wang, Ruifang Liu
Summary: The study investigates the functional variants associated with chicken eggshell color in the SLCO1B3 gene by measuring the eggshell color of Lueyang black-boned chickens and analyzing the genetic data. It identifies 15 variants in SLCO1B3 that are significantly associated with eggshell color. However, the functional analysis shows that one specific variant, 1B3_SNP108, does not have a significant effect on promoter activity. This study highlights the importance of SLCO1B3 and its variants in breeding eggshell color.
Article
Agriculture, Dairy & Animal Science
P. Yin, Q. Tong, B. M. Li, W. C. Zheng, Y. Wang, H. Q. Peng, X. L. Xue, S. Q. Wei
Summary: This study investigated the welfare and health of laying hens in a multitier system. The results showed that the spatial distribution of hens changed with increasing age, and lower-ranking hens preferred to stay in lower tiers to avoid competition but still had access to resources. This improved the welfare and health of the hens near the end of the laying cycle.
Article
Agriculture, Dairy & Animal Science
Wenwen Liang, Siqiong Jie, Yiqin Wang, Xiaowei Wen, Yanling Xiong, Xiaoxi Lin, Zhengrong Lv
Summary: This study examined the effect of risk perceptions on preventive behavior among vendors in the live poultry wholesale market and the live poultry retail market in Guangdong Province using the health belief model and structural equation modeling. The results showed that perceived severity and perceived benefits positively influenced vendors' self-efficacy in the wholesale market, while perceived barriers negatively affected self-efficacy in both the wholesale and retail markets. Moreover, cues to action mediated the relationship between perceived severity, perceived benefits, and self-efficacy, and also mediated the effect of perceived susceptibility among wholesale market vendors.
Article
Agriculture, Dairy & Animal Science
Shreeya Sharma, Raveendra R. Kulkarni, Shayan Sharif, Hosni Hassan, Mohammadali Alizadeh, Scott Pratt, Khaled Abdelaziz
Summary: The study investigates the impact of exposing chick embryos to antigens via in ovo delivery of poultry-specific lactobacilli on the expression of genes associated with early bursal development and maturation. Results indicate that the supplementation of poultry-specific lactobacilli to chick embryos can accelerate the development and immunological maturation of the bursa of Fabricius.