Article
Genetics & Heredity
Xuanze Ling, Qifan Wang, Pengfei Wu, Kaizhi Zhou, Jin Zhang, Genxi Zhang
Summary: This study investigated the potential target genes of miR-24-3p in chicken skeletal muscle. By using RNA-seq, the researchers identified differentially expressed genes and important biological processes and pathways associated with miR-24-3p. Furthermore, they validated the sequencing results through qPCR experiments. These findings have implications for understanding the regulatory role of miR-24-3p in chicken skeletal muscle and provide new directions for broiler breeding research.
Review
Biochemistry & Molecular Biology
Binglin Yue, Hui Wang, Xin Cai, Jiabo Wang, Zhixin Chai, Wei Peng, Shi Shu, Changqi Fu, Jincheng Zhong
Summary: Adipose tissue-secreted exosomes play a significant role in the intercellular communication between organs, especially with skeletal muscle. These exosomes transfer various molecules that can affect the physiological and pathological processes in recipient cells. Therefore, studying the regulatory mechanisms of adipose-secreted exosomes and their cellular crosstalk with skeletal muscle is of great importance.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Genetics & Heredity
Weite Li, Shulei Wen, Jiahan Wu, Bin Zeng, Ting Chen, Junyi Luo, Gang Shu, Song-bo Wang, Yongliang Zhang, Qianyun Xi
Summary: The study revealed that skeletal muscle-derived exosomes can inhibit adipogenesis of porcine preadipocytes, with certain microRNAs enriched in lipid-related metabolism processes. These findings provide a fundamental resource for understanding the detailed functions of exosomes in the skeletal muscle-adipose crosstalk and the potential relationship between skeletal muscle atrophy and obesity.
FRONTIERS IN GENETICS
(2021)
Article
Multidisciplinary Sciences
Takayuki Yamamoto, Kazushi Sugimoto, Syuhei Ichikawa, Kei Suzuki, Hideki Wakabayashi, Kaoru Dohi, Norihiko Yamamoto
Summary: This study investigated the relationship between body composition and the prognosis of COVID-19. The results showed that high intra-muscular adipose tissue content (IMAC) may predict the severe disease course of COVID-19 in non-obese Japanese patients, but it did not predict disease severity in obese patients or mortality.
Review
Endocrinology & Metabolism
Wataru Aoi, Yuko Tanimura
Summary: This passage highlights the importance of muscle-derived exosomes in regulating target protein expression and activity associated with metabolism and immune function. It also discusses the altered levels of circulating exosomes and their contents in muscle disorders and metabolic-related states, suggesting their potential as biomarkers.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Endocrinology & Metabolism
Fang Lv, Xiaoling Cai, Yufeng Li, Zuodi Fu, Xiuying Zhang, Xianghai Zhou, Xueyao Han, Linong Ji
Summary: Body composition is closely related to metabolic health status. In Chinese adults, higher visceral adipose tissue is closely associated with metabolically unhealthy phenotype, while subcutaneous adipose tissue only serves as a protective factor for metabolic health status in obese individuals.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Cell Biology
Donato A. Rivas, Fei Peng, Townsend Benard, Adelino Sanchez Ramos da Silva, Roger A. Fielding, Lee M. Margolis
Summary: The study found that miR-19b-3p plays a crucial role in regulating muscle synthesis, contributing to understanding the varied responses of mobility-limited older adults to anabolic stimuli.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
(2021)
Article
Agriculture, Dairy & Animal Science
Han Wang, Moran Hu, Zhaoxue Ding, Xiaolong Zhou, Songbai Yang, Zhonghao Shen, Feifei Yan, Ayong Zhao
Summary: PHGDH accelerates chicken muscle cell proliferation by increasing FoxM1 expression.
Article
Genetics & Heredity
Hongmei Shi, Jing Fu, Yang He, Zijian Li, Jiajia Kang, Changjie Hu, Xiannian Zi, Yong Liu, Jinbo Zhao, Tengfei Dou, Junjing Jia, Yong Duan, Kun Wang, Changrong Ge
Summary: This study compared the differences in skeletal muscle development between Tengchong snow black meat chickens and white meat chickens, and found that excessive melanin deposition has an effect on skeletal muscle development. The study also validated key candidate genes associated with muscle development and melanin synthesis. The results showed that black meat chickens had inhibited breast and leg muscle development, and melanin deposition was mainly concentrated in the leg muscles, producing an inhibitory effect similar to MSTN.
Article
Cell Biology
Miriam A. Holzman, Abigail Ryckman, Tova M. Finkelstein, Kim Landry-Truchon, Kyra A. Schindler, Jenna M. Bergmann, Lucie Jeannotte, Jennifer H. Mansfield
Summary: Hoxa5 plays a critical role in embryonic BAT development and negatively regulates formation of epaxial muscle. The protein is expressed in embryonic adipocytes as early as day 12.5.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Article
Biotechnology & Applied Microbiology
Pengfei Wu, Kaizhi Zhou, Jin Zhang, Xuanze Ling, Xinchao Zhang, Li Zhang, Peifeng Li, Qingyu Wei, Tao Zhang, Xinglong Wang, Genxi Zhang
Summary: In this study, chicken leg muscles at 14 and 20-day embryo ages were collected from fast- and slow-growing groups for RNA-seq analysis, identifying 245 and 440 differentially expressed circRNAs in the comparison groups F14vsF20 and S14vsS20, respectively. GO enrichment analysis revealed that the host genes of DE circRNAs were related to growth processes, such as transcription regulation, metabolic processes, and myofibril assembly. Further analysis identified key host genes and circRNA-miRNA pairs involved in skeletal muscle development in chickens.
Article
Cardiac & Cardiovascular Systems
Kevin Huynh, Colby Ayers, Javed Butler, Ian Neeland, Stephen Kritchevsky, Ambarish Pandey, Gregory Barton, Jarett D. Berry
Summary: The study found that intramuscular thigh muscle fat is significantly associated with HF risk, especially for HF with reduced ejection fraction. On the other hand, intermuscular thigh muscle fat is not significantly associated with HF risk.
JACC-HEART FAILURE
(2021)
Article
Biochemistry & Molecular Biology
Yanhong Li, Jie Wang, Mauricio A. Elzo, Mingchuan Gan, Tao Tang, Jiahao Shao, Tianfu Lai, Yuan Ma, Xianbo Jia, Songjia Lai
Summary: Through experiments, it was found that in rabbits induced to be obese by a high-fat diet, there were significant differences in the expression of certain miRNAs and core genes, with the miRNAs being able to regulate transcription factors that impact lipid metabolism. These results contribute to a better understanding of the molecular mechanisms of skeletal muscle metabolism in rabbits.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Endocrinology & Metabolism
Shaobo Li, Haoyong Yu, Pin Zhang, Yinfang Tu, Yunfeng Xiao, Di Yang, Yuqian Bao, Junfeng Han, Weiping Jia
Summary: This study found a nonlinear relationship between muscle mass and BMI, and suggested that baseline muscle mass and eFFMI are more reliable predictors of diabetes remission than BMI.
Article
Endocrinology & Metabolism
Shaobo Li, Haoyong Yu, Pin Zhang, Yinfang Tu, Yunfeng Xiao, Di Yang, Yuqian Bao, Junfeng Han, Weiping Jia
Summary: The study found a non-linear relationship between muscle mass and BMI, with psoas muscle mass and eFFMI being better predictors of diabetes remission after Roux-en-Y gastric bypass surgery compared to BMI.
Article
Agriculture, Dairy & Animal Science
Jesper Tessin, Judith Rohde, Arne Jung, Nicole Kemper, Jochen Schulz
Summary: In this study, samples from poultry house environment and culled birds were collected, and E. cecorum was successfully isolated. The principle of isolating the pathogen by streaking on a chromogenic agar may motivate researchers to investigate transmission routes and optimize biosecurity measures.
Article
Agriculture, Dairy & Animal Science
Junqin Zhang, Zimin Xie, Yanlin Pan, Zuoxin Chen, Yunzhen Huang, Linlin Li, Jiawen Dong, Yong Xiang, Qi Zhai, Minhua Sun, Xingying Li, Shujian Huang, Ming Liao
Summary: In recent years, there has been an increase in the occurrence of fowl adenovirus 2 (FAdV-2) in China, posing a significant threat to the poultry industry. This study investigated the epidemiology, phylogenetic relationship, genomic characteristics, and pathogenicity of FAdV-2. The results showed that FAdV-2 was the most commonly detected serotype among various FAdV serotypes. Genetic analysis revealed that these FAdV-2 strains formed a distinct branch within the FAdV-D group and had a high nucleotide similarity with reference strains. Recombination analysis identified recombination events between FAdV-2 and FAdV-11 in some strains. Pathogenicity experiments demonstrated that a recombinant FAdV-2 strain caused a high mortality rate and more severe disease in chickens. These findings contribute to our understanding of FAdV-2 and provide a basis for vaccine development.
Article
Agriculture, Dairy & Animal Science
Ebtsam Iraqi, Ali Abdel Hady, Nadia Elsayed, Hanaa Khalil, Amina El-Saadany, Karim El-Sabrout
Summary: Thermal manipulation during egg incubation, particularly at 12 to 18 days, has positive effects on embryonic development, hatching characteristics, chick quality, as well as posthatch thermotolerance and performance.
Article
Agriculture, Dairy & Animal Science
Yong Liu, Mingxin Song, He Bai, Chunhua Wang, Fei Wang, Qi Yuan
Summary: Dietary curcumin supplementation can significantly improve egg quality of quails in the late laying period, primarily by improving lipid metabolism and selectively regulating the intestinal microbial community.
Article
Agriculture, Dairy & Animal Science
Lei Zhang, Zhixuan Song, Peiyao Li, Xingju Song, Xinming Tang, Dandan Hu
Summary: This study evaluated the vaccine potential of recombinant proteins for avian coccidiosis caused by Eimeria. The results showed that the rEten5-B protein can trigger immune protection against E. tenella and may be a potential and effective subunit vaccine for the control of coccidiosis in poultry.
Article
Agriculture, Dairy & Animal Science
Milan Kumar Sharma, Amit Kumar Singh, Doyun Goo, Venkata Sesha Reddy Choppa, Hanseo Ko, Hanyi Shi, Woo Kyun Kim
Summary: The study investigates the effect of Eimeria infection on gastrointestinal physiology, growth performance, and egg production of Hy-Line W-36 laying hens during peak production. Results show that Eimeria infection negatively affects body weight, feed intake, immune response, and nutrient transporter gene expression. Egg production temporarily ceases in hens infected with high and medium-high dosages of Eimeria.
Article
Agriculture, Dairy & Animal Science
Elwy A. Ashour, Mahmoud Kamal, Hayman A. A. Altaie, Ayman A. Swelum, Gamaleldin M. Suliman, Guillermo Tellez-Isaias, Mohamed E. Abd El-Hack
Summary: This study evaluated the effects of CP and ME on the performance and nutritional value of Japanese quail lay chicken. The results showed that protein and energy levels significantly influenced all productive outcomes except feed conversion ratio. The combination of dietary energy and protein levels had a substantial effect on all egg quality trials evaluated. It is recommended to feed layer Japanese quail between the ages of 8 and 20 weeks during the summer with a dietary energy content of 2,900 kcal ME/kg and 20% CP.
Article
Agriculture, Dairy & Animal Science
J. E. Doornweerd, R. F. Veerkamp, B. de Klerk, M. van der Sluis, A. C. Bouwman, E. D. Ellen, G. Kootstra
Summary: Tracking group-housed individual broilers using video can provide valuable information on their health, welfare, and performance. This study conducted a comprehensive analysis on broiler tracking on video and potential tracking errors, highlighting the potential and challenges of phenotyping broiler locomotion. The results emphasized the importance of addressing tracking errors, potential algorithm improvements, and the need for an external animal identification system for efficient locomotion phenotyping.
Article
Agriculture, Dairy & Animal Science
Jiayu Wu, Yanan Wang, Yu An, Changyu Tian, Lingfeng Wang, Zuhong Liu, Desheng Qi
Summary: This study compared the gene expression differences in liver tissues of laying hens at different ages using RNA sequencing, and found that the transport and metabolism of amino acids changed during the growing period, which influenced the growth and development of the hens.
Article
Agriculture, Dairy & Animal Science
J. Raabe, G. Raveendran, W. Otten, K. Homeyer, T. Bartels
Summary: This study investigated the effects of different flicker frequencies on the behavior, performance, and stress response in male turkeys. The results showed that flicker frequencies of 165 Hz or higher had no detrimental effect on growth performance, injurious pecking, or endocrine stress response in the turkeys.
Article
Agriculture, Dairy & Animal Science
Adamu Mani Isa, Yanyan Sun, Yuanmei Wang, Yunlei Li, Jingwei Yuan, Aixin Ni, Hui Ma, Lei Shi, Hailai Hagos Tesfay, Yunhe Zong, Panlin Wang, Pingzhuang Ge, Jilan Chen
Summary: This study sequenced mRNAs and lncRNAs in the ovary stroma of specific chicken breeds and their reciprocal crossbreds to understand the molecular mechanism of heterosis for egg production. Results showed that genes with nonadditive expression were related to follicle growth and atresia as well as oxidative stress in the crossbred hens.
Article
Agriculture, Dairy & Animal Science
Zhepeng Wang, Qiu Chen, Yiwei Wang, Yulu Wang, Ruifang Liu
Summary: The study investigates the functional variants associated with chicken eggshell color in the SLCO1B3 gene by measuring the eggshell color of Lueyang black-boned chickens and analyzing the genetic data. It identifies 15 variants in SLCO1B3 that are significantly associated with eggshell color. However, the functional analysis shows that one specific variant, 1B3_SNP108, does not have a significant effect on promoter activity. This study highlights the importance of SLCO1B3 and its variants in breeding eggshell color.
Article
Agriculture, Dairy & Animal Science
P. Yin, Q. Tong, B. M. Li, W. C. Zheng, Y. Wang, H. Q. Peng, X. L. Xue, S. Q. Wei
Summary: This study investigated the welfare and health of laying hens in a multitier system. The results showed that the spatial distribution of hens changed with increasing age, and lower-ranking hens preferred to stay in lower tiers to avoid competition but still had access to resources. This improved the welfare and health of the hens near the end of the laying cycle.
Article
Agriculture, Dairy & Animal Science
Wenwen Liang, Siqiong Jie, Yiqin Wang, Xiaowei Wen, Yanling Xiong, Xiaoxi Lin, Zhengrong Lv
Summary: This study examined the effect of risk perceptions on preventive behavior among vendors in the live poultry wholesale market and the live poultry retail market in Guangdong Province using the health belief model and structural equation modeling. The results showed that perceived severity and perceived benefits positively influenced vendors' self-efficacy in the wholesale market, while perceived barriers negatively affected self-efficacy in both the wholesale and retail markets. Moreover, cues to action mediated the relationship between perceived severity, perceived benefits, and self-efficacy, and also mediated the effect of perceived susceptibility among wholesale market vendors.
Article
Agriculture, Dairy & Animal Science
Shreeya Sharma, Raveendra R. Kulkarni, Shayan Sharif, Hosni Hassan, Mohammadali Alizadeh, Scott Pratt, Khaled Abdelaziz
Summary: The study investigates the impact of exposing chick embryos to antigens via in ovo delivery of poultry-specific lactobacilli on the expression of genes associated with early bursal development and maturation. Results indicate that the supplementation of poultry-specific lactobacilli to chick embryos can accelerate the development and immunological maturation of the bursa of Fabricius.