Article
Medicine, General & Internal
Mieko Tokano, Norihito Tarumoto, Kazuo Imai, Jun Sakai, Takuya Maeda, Toru Kawamura, Kazuhide Seo, Kazushi Takahashi, Toshimasa Yamamoto, Shigefumi Maesaki
Summary: A 67-year-old woman with fever, headache, and disturbed consciousness for 2 days was admitted to the hospital. Bacillus subtilis was isolated from both her cerebrospinal fluid and blood. She was successfully treated with vancomycin. Next-generation sequencing identified the strain as B. subtilis var. natto, the same strain found in the fermented soybean product natto, which the patient consumed daily. We suspect that some of the B. subtilis causing the infection might actually be B. subtilis var. natto.
Article
Agriculture, Multidisciplinary
Hsin-Ya Tsai, Ming-Yu Chen, Chen Hsu, Kai-Yuan Kuan, Chi-Fon Chang, Che-Wei Wang, Chao-Ping Hsu, Nan-Wei Su
Summary: This study revealed the bioconversion of luteolin by Bacillus subtilis BCRC 80517, resulting in the production of three water-soluble phosphate conjugates. It was found that luteolin disrupted bacterial membrane integrity, leading to incomplete conversion. Additionally, a spontaneous intramolecular transesterification of one of the derivatives was observed under acidic conditions.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2022)
Article
Food Science & Technology
Vasilios Tsiouris, Panagiotis Tassis, Jog Raj, Tilemachos Mantzios, Konstantinos Kiskinis, Marko Vasiljevic, Nikola Delic, Evanthia Petridou, Georgia D. Brellou, Zoe Polizopoulou, Nikolaos Mittas, Ioanna Georgopoulou
Summary: The study demonstrated that the supplementation of MMDA significantly improved the adverse effects of AFB(1) and OTA in broilers, including increased feed conversion ratio, reduced biochemical alterations, decreased intestinal pH values, and lower E. coli counts in the ceca of birds.
Article
Biochemistry & Molecular Biology
Grzegorz Klosowski, Dawid Mikulski, Katarzyna Pielech-Przybylska
Summary: This study isolated two Bacillus subtilis strains capable of producing a variety of alkylpyrazines, showing that different strains have different abilities for alkylpyrazine biosynthesis.
Article
Nutrition & Dietetics
Kanako Kono, Yasufumi Murakami, Aya Ebara, Kana Okuma, Hidetaka Tokuno, Ayano Odachi, Kazuya Ogasawara, Emi Hidaka, Teruaki Mori, Kazuko Satoh, Shingen Kimoto, Hiroaki Masuyama, Midori Takeda, Shunsuke Managi
Summary: This study discusses the effects of food intake on intestinal microbiota using a large Japanese database. The ingestion of processed food containing B. subtilis var. natto spores was found to increase the relative abundance of Bifidobacterium and Blautia in males and females, respectively. Furthermore, the impact of the food intake on the abundance of Bifidobacterium and Blautia depended on the initial abundance of Bifidobacterium. Analysis of the database also suggested a potential association between the fluctuation of bacterial genera with the ingestion of the food and lifestyle-related diseases such as diabetes.
Article
Microbiology
Cecilia Lenini, Facundo Rodriguez Ayala, Anibal Juan Goni, Liliana Rateni, Akira Nakamura, Roberto Ricardo Grau
Summary: This paper reports the isolation and characterization of a spore-forming probiotic strain Bacillus subtilis DG101 from the traditional Japanese food natto. The strain showed high stability, tolerance to adverse conditions, and potential benefits for human health, such as competitive exclusion of pathogens, improvement of food diet digestion, bioremediation of metal poisoning, antimicrobial activity, and enhancement of serum homeostasis and longevity in animal models. Overall, Bacillus subtilis DG101 is a key component of natto with interesting probiotic properties to improve and protect human health.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Biotechnology & Applied Microbiology
R. Katayama, Y. Matsumoto, Y. Higashi, S. Sun, H. Sasao, Y. Tanimoto, Y. Nishikawa, E. Kage-Nakadai
Summary: This study showed that Bacillus subtilis (natto) can enhance the resistance of Caenorhabditis elegans to gram-positive bacteria and increase the survival time of the worms upon infection. Transcriptome analysis revealed the upregulation of genes associated with immunity and defense response in B. subtilis (natto)-fed worms.
JOURNAL OF APPLIED MICROBIOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Mami Oba, Wen Rongduo, Akatsuki Saito, Tamaki Okabayashi, Tomoko Yokota, Junko Yasuoka, Yoko Sato, Koji Nishifuji, Hitoshi Wake, Yutaka Nibu, Tetsuya Mizutani
Summary: The study demonstrated that a protease present in natto extract inhibits SARS-CoV-2 and BHV-1 infection by degrading viral proteins. However, heat treatment of the natto extract reverses this inhibitory effect.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
(2021)
Article
Environmental Sciences
Hongfei Lu, Xuebin Qi, Shafeeq Ur Rahman, Dongmei Qiao, Ping Li, Yang Han, Zhijuan Zhao
Summary: The increasing salinity levels under reclaimed water irrigation have negative effects on plant growth, but the combination of B. subtilis and S. cerevisiae can promote rice physiological indices, with B. subtilis having a greater effect. Soil nitrogen concentration and the amount of B. subtilis applied are major factors influencing leaf physiological indices.
Article
Microbiology
Ida Szmigiel, Damian Konkol, Mariusz Korczynski, Marcin Lukaszewicz, Anna Krasowska
Summary: This study found that the addition of 3% fermented rapeseed meal led to beneficial histological changes in the ceca of broiler chickens, inhibited the growth of pathogens, and stimulated the growth of probiotic bacteria.
Article
Multidisciplinary Sciences
Gamonmas Dagaew, Sawitree Wongtangtintharn, Chanon Suntara, Rittikeard Prachumchai, Metha Wanapat, Anusorn Cherdthong
Summary: The study aimed to investigate the effects of substituting cassava pulp fermented yeast waste (CSYW) for soybean meal (SBM) on feed intake, digestibility, and rumen fermentation in Thai native beef cattle. The results showed that CSYW had no negative impact on feed intake, nutritional intake, or apparent digestibility. However, it increased the rumen ammonia-nitrogen concentration, total bacterial population, and propionic acid concentration.
SCIENTIFIC REPORTS
(2022)
Article
Agricultural Engineering
Hongfei Lu, Xuebin Qi, Ping Li, Dongmei Qiao, Shafeeq-ur-Rahman, Fangfang Bai, Jiaxin Cui
Summary: Reclaimed water-fresh water combined irrigation increased the plant height and yield of rice. Inoculation with Bacillus subtilis and Saccharomyces cerevisiae enhanced nutrient absorption capacity and improved soil fertility and texture, while reducing soil salt accumulation.
INTERNATIONAL JOURNAL OF AGRICULTURAL AND BIOLOGICAL ENGINEERING
(2022)
Article
Biotechnology & Applied Microbiology
Yukun Zhang, Manabu Ishikawa, Shunsuke Koshio, Saichiro Yokoyama, Serge Dossou, Weilong Wang, Xiaoxiao Zhang, Ronick Spenly Shadrack, Kumbukani Mzengereza, Kehua Zhu, Seok Seo
Summary: This study aimed to improve the nutritional value of soybean meal through solid-state fermentation with Bacillus subtilis natto. The optimum fermentation conditions resulted in significantly higher protein hydrolysis and crude protein content, while reducing anti-nutritional factors. The fermented soybean meal showed increased essential amino acids content and decreased anti-nutritional factors, indicating great potential for aquafeed applications.
FERMENTATION-BASEL
(2021)
Article
Food Science & Technology
Huei-Ju Wang, Lin Chang, Yu-Shiun Lin
Summary: Fermenting germinated brown rice (GBR) with Bacillus natto results in higher nutritional value and functional properties compared to fermented brown rice (BR) or white rice (WR).
Article
Fisheries
Eman Y. Mohammady, Ahmed M. Aboseif, Mohamed R. Soaudy, Enas A. Ramadan, Mohamed S. Hassaan
Summary: This study investigated the impact of fermenting wheat bran with baker's yeast on its fiber and protein content, as well as its effects on the growth and health of Nile tilapia. The fermentation process reduced fiber content, increased protein content, and improved amino acid profile. Feeding tilapia diets with yeast-fermented wheat bran led to enhanced development, feed utilization, and blood indices. The inclusion of yeast-fermented wheat bran at 20% in the diets resulted in the best growth performance. The study also found that the inclusion of yeast-fermented wheat bran had no significant effect on the composition of the diets.
Article
Agriculture, Dairy & Animal Science
Kuo-Lung Chen, Pei-Chun Tu, Chean-Ping Wu, Tsai-Tzu Chen, YaoChi Su, Sheng-Ya Chen, Chishih Chu
JOURNAL OF POULTRY SCIENCE
(2016)
Article
Biochemical Research Methods
Chien-Hsun Huang, Lina Huang, Mu-Tzu Chang, Kuo-Lung Chen
MOLECULAR AND CELLULAR PROBES
(2016)
Article
Pharmacology & Pharmacy
Po-Min Yang, Yu-Ting Huang, Yu-Qi Zhang, Chia-Wen Hsieh, Being-Sun Wung
VASCULAR PHARMACOLOGY
(2016)
Article
Medicine, Research & Experimental
Po-Min Yang, Huang-Zhi Chen, Yu-Ting Huang, Chia-Wen Hsieh, Being-Sun Wung
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
(2017)
Article
Agriculture, Dairy & Animal Science
Ruei Han Yeh, Chia Wen Hsieh, Kuo Lung Chen
Article
Oncology
Chiawen Hsieh, Yun-Wei Lin, Ching-Hsein Chen, Wenjun Ku, Fuching Ma, Hanming Yu, Chishih Chu
Article
Pharmacology & Pharmacy
Po-Min Yang, Kai-Chun Cheng, Jing-Yao Huang, Shih-Yun Wang, Yung-Ni Lin, Yen-Tzu Tseng, Chia-Wen Hsieh, Being-Sun Wung
Summary: The study revealed that SFN protects RPE cells from blue light-induced damage by activating the Nrf2 pathway and inhibiting NF-KB nuclear translocation, showing antioxidant, anti-inflammatory, anti-apoptotic, and autophagy-promoting effects.
TOXICOLOGY AND APPLIED PHARMACOLOGY
(2021)
Article
Agriculture, Dairy & Animal Science
Hsien-Juang Huang, Bor-Chun Weng, Yan-Der Hsuuw, Yueh-Sheng Lee, Kuo-Lung Chen
Summary: The study demonstrated that feeding pigs with 2.5-5% TSFP can improve average daily feed intake and feed conversion rate. The 5% TSFP group showed increased HDL-C, decreased LDL-C and blood urea nitrogen content, as well as enhanced lymphoblastogenesis, IFN-gamma and IgA production, and phagocytic cells oxygen burst capacity. This suggests that TSFP has positive effects on growth performance and immunity of finishing pigs.
Article
Biology
Istiqomah Hariyanto, Chia-Wen Hsieh, Yueh-Han Hsu, Lih-Geng Chen, ChiShih Chu, Brian Bor-Chun Weng
Summary: Soy isoflavones have various health benefits, and the solid-state fermentation of soybean residue can increase the levels of isoflavones and GABA, improving hyperglycemic symptoms.
Article
Biotechnology & Applied Microbiology
Ruei-Han Yeh, Chia-Wen Hsieh, Kuo-Lung Chen
Summary: This study aimed to investigate the dose tolerance of enzymatically degraded feather meal (EFM) in the diet and the effect of two-stage fermented feather meal on the growth performance and amino acid digestibility of broilers. The results showed that dietary inclusion of more than 15% EFM had a negative impact on growth performance, while the inclusion of Bacillius subtilis var. natto N21 + S. cerevisiae Y10 fermented EFM improved amino acid digestibility and broiler growth performance.
FERMENTATION-BASEL
(2023)
Article
Biotechnology & Applied Microbiology
Hsien-Juang Huang, Yueh-Sheng Lee, Bor-Chun Weng, Cheng-Yung Lin, Yan-Der Hsuuw, Kuo-Lung Chen
Summary: This study investigated the effects of TSFP on the performance, clinical blood biochemistry, and immunity of sows and piglets. The results showed that the 2% and 3% TSFP groups had better weight gain and feed conversion ratio during gestation. In addition, the 3% TSFP group showed the best weaning litter weight and improved immune function.
FERMENTATION-BASEL
(2023)
Article
Biotechnology & Applied Microbiology
Weng-Keong Lo, Ping-Lin Ong, Yueh-Sheng Lee, Yi-Tai Hsu, Kuo-Lung Chen
Summary: This study screened the proteolytic activity of Bacillus species in meat and bone meal and investigated the effects of fermented meat and bone meal-soybean meal products on the growth performance of broilers. The results showed that Bacillus subtilis M6 efficiently decomposed meat and bone meal-soybean meal and improved the protein properties and nutritional value of the product. Furthermore, supplementation with 5% fermented meat and bone meal-soybean meal products promoted weight gain in broilers.
FERMENTATION-BASEL
(2023)
Article
Biotechnology & Applied Microbiology
Hsien-Juang Huang, Bor-Chun Weng, Yueh-Sheng Lee, Cheng-Yung Lin, Yan-Der Hsuuw, Kuo-Lung Chen
Summary: This study demonstrated that supplementing nursery pigs with 5% TSFP produced through a 32-hour first-stage fermentation using selected Bacillus strains resulted in improved growth performance and immunity.
FERMENTATION-BASEL
(2022)
Article
Biotechnology & Applied Microbiology
Yu-Fan Liu, Chia-Wen Hsieh, Yao-Sheng Chang, Being-Sun Wung
Article
Agriculture, Dairy & Animal Science
Jesper Tessin, Judith Rohde, Arne Jung, Nicole Kemper, Jochen Schulz
Summary: In this study, samples from poultry house environment and culled birds were collected, and E. cecorum was successfully isolated. The principle of isolating the pathogen by streaking on a chromogenic agar may motivate researchers to investigate transmission routes and optimize biosecurity measures.
Article
Agriculture, Dairy & Animal Science
Junqin Zhang, Zimin Xie, Yanlin Pan, Zuoxin Chen, Yunzhen Huang, Linlin Li, Jiawen Dong, Yong Xiang, Qi Zhai, Minhua Sun, Xingying Li, Shujian Huang, Ming Liao
Summary: In recent years, there has been an increase in the occurrence of fowl adenovirus 2 (FAdV-2) in China, posing a significant threat to the poultry industry. This study investigated the epidemiology, phylogenetic relationship, genomic characteristics, and pathogenicity of FAdV-2. The results showed that FAdV-2 was the most commonly detected serotype among various FAdV serotypes. Genetic analysis revealed that these FAdV-2 strains formed a distinct branch within the FAdV-D group and had a high nucleotide similarity with reference strains. Recombination analysis identified recombination events between FAdV-2 and FAdV-11 in some strains. Pathogenicity experiments demonstrated that a recombinant FAdV-2 strain caused a high mortality rate and more severe disease in chickens. These findings contribute to our understanding of FAdV-2 and provide a basis for vaccine development.
Article
Agriculture, Dairy & Animal Science
Ebtsam Iraqi, Ali Abdel Hady, Nadia Elsayed, Hanaa Khalil, Amina El-Saadany, Karim El-Sabrout
Summary: Thermal manipulation during egg incubation, particularly at 12 to 18 days, has positive effects on embryonic development, hatching characteristics, chick quality, as well as posthatch thermotolerance and performance.
Article
Agriculture, Dairy & Animal Science
Yong Liu, Mingxin Song, He Bai, Chunhua Wang, Fei Wang, Qi Yuan
Summary: Dietary curcumin supplementation can significantly improve egg quality of quails in the late laying period, primarily by improving lipid metabolism and selectively regulating the intestinal microbial community.
Article
Agriculture, Dairy & Animal Science
Lei Zhang, Zhixuan Song, Peiyao Li, Xingju Song, Xinming Tang, Dandan Hu
Summary: This study evaluated the vaccine potential of recombinant proteins for avian coccidiosis caused by Eimeria. The results showed that the rEten5-B protein can trigger immune protection against E. tenella and may be a potential and effective subunit vaccine for the control of coccidiosis in poultry.
Article
Agriculture, Dairy & Animal Science
Milan Kumar Sharma, Amit Kumar Singh, Doyun Goo, Venkata Sesha Reddy Choppa, Hanseo Ko, Hanyi Shi, Woo Kyun Kim
Summary: The study investigates the effect of Eimeria infection on gastrointestinal physiology, growth performance, and egg production of Hy-Line W-36 laying hens during peak production. Results show that Eimeria infection negatively affects body weight, feed intake, immune response, and nutrient transporter gene expression. Egg production temporarily ceases in hens infected with high and medium-high dosages of Eimeria.
Article
Agriculture, Dairy & Animal Science
Elwy A. Ashour, Mahmoud Kamal, Hayman A. A. Altaie, Ayman A. Swelum, Gamaleldin M. Suliman, Guillermo Tellez-Isaias, Mohamed E. Abd El-Hack
Summary: This study evaluated the effects of CP and ME on the performance and nutritional value of Japanese quail lay chicken. The results showed that protein and energy levels significantly influenced all productive outcomes except feed conversion ratio. The combination of dietary energy and protein levels had a substantial effect on all egg quality trials evaluated. It is recommended to feed layer Japanese quail between the ages of 8 and 20 weeks during the summer with a dietary energy content of 2,900 kcal ME/kg and 20% CP.
Article
Agriculture, Dairy & Animal Science
J. E. Doornweerd, R. F. Veerkamp, B. de Klerk, M. van der Sluis, A. C. Bouwman, E. D. Ellen, G. Kootstra
Summary: Tracking group-housed individual broilers using video can provide valuable information on their health, welfare, and performance. This study conducted a comprehensive analysis on broiler tracking on video and potential tracking errors, highlighting the potential and challenges of phenotyping broiler locomotion. The results emphasized the importance of addressing tracking errors, potential algorithm improvements, and the need for an external animal identification system for efficient locomotion phenotyping.
Article
Agriculture, Dairy & Animal Science
Jiayu Wu, Yanan Wang, Yu An, Changyu Tian, Lingfeng Wang, Zuhong Liu, Desheng Qi
Summary: This study compared the gene expression differences in liver tissues of laying hens at different ages using RNA sequencing, and found that the transport and metabolism of amino acids changed during the growing period, which influenced the growth and development of the hens.
Article
Agriculture, Dairy & Animal Science
J. Raabe, G. Raveendran, W. Otten, K. Homeyer, T. Bartels
Summary: This study investigated the effects of different flicker frequencies on the behavior, performance, and stress response in male turkeys. The results showed that flicker frequencies of 165 Hz or higher had no detrimental effect on growth performance, injurious pecking, or endocrine stress response in the turkeys.
Article
Agriculture, Dairy & Animal Science
Adamu Mani Isa, Yanyan Sun, Yuanmei Wang, Yunlei Li, Jingwei Yuan, Aixin Ni, Hui Ma, Lei Shi, Hailai Hagos Tesfay, Yunhe Zong, Panlin Wang, Pingzhuang Ge, Jilan Chen
Summary: This study sequenced mRNAs and lncRNAs in the ovary stroma of specific chicken breeds and their reciprocal crossbreds to understand the molecular mechanism of heterosis for egg production. Results showed that genes with nonadditive expression were related to follicle growth and atresia as well as oxidative stress in the crossbred hens.
Article
Agriculture, Dairy & Animal Science
Zhepeng Wang, Qiu Chen, Yiwei Wang, Yulu Wang, Ruifang Liu
Summary: The study investigates the functional variants associated with chicken eggshell color in the SLCO1B3 gene by measuring the eggshell color of Lueyang black-boned chickens and analyzing the genetic data. It identifies 15 variants in SLCO1B3 that are significantly associated with eggshell color. However, the functional analysis shows that one specific variant, 1B3_SNP108, does not have a significant effect on promoter activity. This study highlights the importance of SLCO1B3 and its variants in breeding eggshell color.
Article
Agriculture, Dairy & Animal Science
P. Yin, Q. Tong, B. M. Li, W. C. Zheng, Y. Wang, H. Q. Peng, X. L. Xue, S. Q. Wei
Summary: This study investigated the welfare and health of laying hens in a multitier system. The results showed that the spatial distribution of hens changed with increasing age, and lower-ranking hens preferred to stay in lower tiers to avoid competition but still had access to resources. This improved the welfare and health of the hens near the end of the laying cycle.
Article
Agriculture, Dairy & Animal Science
Wenwen Liang, Siqiong Jie, Yiqin Wang, Xiaowei Wen, Yanling Xiong, Xiaoxi Lin, Zhengrong Lv
Summary: This study examined the effect of risk perceptions on preventive behavior among vendors in the live poultry wholesale market and the live poultry retail market in Guangdong Province using the health belief model and structural equation modeling. The results showed that perceived severity and perceived benefits positively influenced vendors' self-efficacy in the wholesale market, while perceived barriers negatively affected self-efficacy in both the wholesale and retail markets. Moreover, cues to action mediated the relationship between perceived severity, perceived benefits, and self-efficacy, and also mediated the effect of perceived susceptibility among wholesale market vendors.
Article
Agriculture, Dairy & Animal Science
Shreeya Sharma, Raveendra R. Kulkarni, Shayan Sharif, Hosni Hassan, Mohammadali Alizadeh, Scott Pratt, Khaled Abdelaziz
Summary: The study investigates the impact of exposing chick embryos to antigens via in ovo delivery of poultry-specific lactobacilli on the expression of genes associated with early bursal development and maturation. Results indicate that the supplementation of poultry-specific lactobacilli to chick embryos can accelerate the development and immunological maturation of the bursa of Fabricius.
