Article
Biochemistry & Molecular Biology
Marco De Giovanni, Hanson Tam, Colin Valet, Ying Xu, Mark R. Looney, Jason G. Cyster
Summary: The G-protein-coupled receptor GPR35 is upregulated in activated neutrophils and plays a crucial role in their migration. The platelet-derived serotonin metabolite 5-HIAA acts as a ligand for GPR35 and promotes neutrophil recruitment to sites of inflammation via platelets and mast cells.
Article
Biochemistry & Molecular Biology
Hyun-Seung Lee, Sang-Mi Kim, Ja-Hyun Jang, Hyung-Doo Park, Soo-Youn Lee
Summary: The study found that the increased ratio of 5-hydroxyindoleacetic acid to serotonin may serve as a surrogate marker for VAKI, reflecting acute oxidative stress and inflammation.
Review
Plant Sciences
Pratik Doshi, Bozena Sera
Summary: Different control strategies have been tested against Fusarium spp., including non-thermal plasma technique. Further research is needed in this area, and a potential novel integrated pest management strategy against Fusarium spp. is proposed.
Article
Electrochemistry
Sonia Sam, Goldamol S. Pallam, K. Girish Kumar
Summary: In this report, the first voltammetric sensor for simultaneous determination of neuroendocrine tumour biomarkers 5-Hydroxy indole acetic acid (HIAA) and Vannillyl mandelic acid (VMA) is presented. A glassy carbon electrode modified with a copolymer of taurine and glutamic acid was used to detect the analytes. The combined effect of the two conducting polymers showed significant voltammetric response for the biomarkers. Calibration measurements were conducted using a fast and feasible square wave voltammetric technique. The voltammetric sensor achieved detection limits as low as 4.19 x 10(-8) M (HIAA) and 6.16 x 10(-8) M (VMA) with tolerable interference from coexisting species. Additionally, spike recovery analysis of the analytes in artificial urine samples showed adequate recovery values, demonstrating the reliability of the sensor.
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
(2023)
Review
Chemistry, Medicinal
Dong-Soon Im
Summary: GPR35, an orphan receptor, has been found to have 5-HIAA as a high potency ligand, and a transgenic knock-in mouse line with human ortholog of GPR35 has been developed for therapeutic experiments. This article reviews the recent advances and prospective therapeutic directions in GPR35 research.
ARCHIVES OF PHARMACAL RESEARCH
(2023)
Article
Medicine, General & Internal
Takeshi Tanaka, Masahiko Mori, Masato Tashiro, Koichi Izumikawa
Summary: Plasma 5-HIAA is identified as a biomarker for the severity of ARDS and is a strong predictor for mortality rate, highlighting the importance of evaluating vascular leakage levels in ARDS treatment.
FRONTIERS IN MEDICINE
(2021)
Article
Microbiology
Bimal Paudel, Connor Pedersen, Yang Yen, Shin-Yi Lee Marzano
Summary: Research identified that DON toxin production by F. graminearum during infection of small grain crops is a major contributor to economic losses. A novel strain of Fusarium graminearum virus 1 (FgV1-SD4) was discovered, which showed reduced virulence of F. graminearum against wheat and decreased DON accumulation in infected seeds. This mycovirus strain and specific genetic components of FgV1-SD4 could be further optimized as a biocontrol agent to reduce Fusarium head blight and DON accumulation in small grain crops.
Article
Biochemical Research Methods
Ying Shen, Xia Luo, Qing Guan, Liming Cheng
Summary: A fast, simple, and reliable LC-MS/MS method has been developed and validated for the determination of 24-hour urinary 5-HIAA, and the quality assurance for post-implementation monitoring has been explored. The reference interval of 24-hour urinary 5HIAA in Chinese adults has been established, ensuring reliable and comparable results in routine clinical testing. This LC-MS/MS method can be proposed as a clinical testing tool for urinary 5-HIAA in quality-controlled environments.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
(2022)
Article
Food Science & Technology
Marcin Wit, Piotr Ochodzki, Roman Warzecha, Emilia Jablonska, Ewa Mirzwa-Mroz, Elzbieta Mielniczuk, Wojciech Wakulinski
Summary: This study found significant variation in the host response to Fusarium ear rot among different maize types. Dent-type kernels had significantly lower amylose content and significantly higher infection rates and beauvericin contamination compared to flint maize subpopulation. The study also showed a significant positive correlation between the severity of Fusarium ear rot and ergosterol content, as well as the presence of beauvericin. Furthermore, there was a negative correlation between the severity of Fusarium ear rot and amylose content, indicating the importance of endosperm starch composition in kernel resistance to the disease.
Article
Plant Sciences
Catherine Jimenez-Quiros, Emeka C. Okechukwu, Yiguo Hong, Omur Baysal, Mahmut Tor
Summary: The Bacillus strain EU07 showed better performance in inhibiting the growth of Fusarium graminearum and displayed significant antagonistic activity both in vitro and in planta. It was not affected by mycotoxins and promoted plant growth, suggesting its potential for molecular investigations and protection of cereal crops against FHB disease.
Review
Food Science & Technology
Carolyn W. Kinkade, Zorimar Rivera-Nunez, Ludwik Gorcyzca, Lauren M. Aleksunes, Emily S. Barrett
Summary: Research suggests that mycotoxins like Zearalenone can have adverse effects on the female reproductive system, including infertility, ovarian disorders, and pregnancy complications.
Review
Biotechnology & Applied Microbiology
Vishwambar D. Navale, KoteswaraRao Vamkudoth
Summary: Mycotoxin contamination of food and feed is a serious issue, and the use of lactic acid bacteria (LAB) for mycotoxin management is a more effective, eco-friendly, and cost-effective approach.
BIOTECHNOLOGY LETTERS
(2022)
Article
Food Science & Technology
Asmaa Abbas, Tapani Yli-Mattila
Summary: This study demonstrates that treatment with the methanolic extract of Zanthoxylum bungeanum can reduce the growth of F. graminearum and inhibit the production of deoxynivalenol. The extract is mainly composed of four flavonoids. In vitro bioassays show that the extract can inhibit fungal growth. After biocontrol treatment, the levels of F. graminearum DNA and deoxynivalenol were reduced.
Review
Biochemistry & Molecular Biology
Ning Liu, Shiqiang Sun, Pengjie Wang, Yanan Sun, Qingjuan Hu, Xiaoyu Wang
Summary: Serotonin, also known as 5-hydroxytryptamine (5-HT), is a crucial neurotransmitter synthesized and secreted by enterochromaffin (EC) cells in the gastrointestinal tract. Gut microbiota, nutrients, and hormones play key roles in regulating 5-HT secretion. Understanding the regulatory mechanisms of 5-HT in the immune system can potentially provide therapeutic strategies for treating intestinal diseases.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Plant Sciences
Imane Laraba, Todd J. Ward, Miroslava Cuperlovic-Culf, Hilda Azimi, Pengcheng Xi, Susan P. Mccormick, William T. Hay, Guixia Hao, Martha M. Vaughan
Summary: Fusarium head blight (FHB) is an economically devastating fungal disease of wheat and other small grains, with Fusarium graminearum (Fg) being the predominant etiological agent. In this study, three genetic populations of Fg in North America were identified, and their differences in aggressiveness and mycotoxin production were assessed. The NA3 population was found to be less aggressive than NA1 and NA2 populations but had a similar mycotoxigenic potential. Furthermore, the severity difference in NA3 was not solely due to mycotoxin production or host defense mechanisms.
Article
Agriculture, Dairy & Animal Science
M. Toghyani, C. K. Girish, S. B. Wu, P. A. Iji, R. A. Swick
Article
Agriculture, Dairy & Animal Science
Nishchal K. Sharma, Mingan Choct, Mehdi Toghyani, Yan C. S. M. Laurenson, C. K. Girish, Robert A. Swick
Article
Food Science & Technology
C. K. Girish, T. K. Smith, H. J. Boermans, P. Anil Kumar, G. N. Girgis
FOOD AND CHEMICAL TOXICOLOGY
(2010)
Article
Agriculture, Dairy & Animal Science
C. K. Girish, T. K. Smith, H. J. Boermans, N. A. Karrow
Article
Agriculture, Dairy & Animal Science
C. K. Girish, T. K. Smith
Article
Immunology
George N. Girgis, John R. Barta, Channarayapatna K. Girish, Niel A. Karrow, Herman J. Boermans, Trevor K. Smith
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY
(2010)
Article
Agriculture, Dairy & Animal Science
A. W. Mtei, M. R. Abdollahi, N. Schreurs, C. K. Girish, V Ravindran
Article
Agriculture, Dairy & Animal Science
M. Hilliar, N. Huyen, C. K. Girish, R. Barekatain, S. Wu, R. A. Swick
Article
Agriculture, Dairy & Animal Science
M. Hilliar, G. Hargreave, C. K. Girish, R. Barekatain, S-B Wu, R. A. Swick
Article
Agriculture, Dairy & Animal Science
M. Hilliar, C. Keerqin, C. K. Girish, R. Barekatain, S-B Wu, R. A. Swick
Article
Agriculture, Dairy & Animal Science
CK Girish, C Devegowda
ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES
(2006)
Article
Agriculture, Dairy & Animal Science
Jesper Tessin, Judith Rohde, Arne Jung, Nicole Kemper, Jochen Schulz
Summary: In this study, samples from poultry house environment and culled birds were collected, and E. cecorum was successfully isolated. The principle of isolating the pathogen by streaking on a chromogenic agar may motivate researchers to investigate transmission routes and optimize biosecurity measures.
Article
Agriculture, Dairy & Animal Science
Junqin Zhang, Zimin Xie, Yanlin Pan, Zuoxin Chen, Yunzhen Huang, Linlin Li, Jiawen Dong, Yong Xiang, Qi Zhai, Minhua Sun, Xingying Li, Shujian Huang, Ming Liao
Summary: In recent years, there has been an increase in the occurrence of fowl adenovirus 2 (FAdV-2) in China, posing a significant threat to the poultry industry. This study investigated the epidemiology, phylogenetic relationship, genomic characteristics, and pathogenicity of FAdV-2. The results showed that FAdV-2 was the most commonly detected serotype among various FAdV serotypes. Genetic analysis revealed that these FAdV-2 strains formed a distinct branch within the FAdV-D group and had a high nucleotide similarity with reference strains. Recombination analysis identified recombination events between FAdV-2 and FAdV-11 in some strains. Pathogenicity experiments demonstrated that a recombinant FAdV-2 strain caused a high mortality rate and more severe disease in chickens. These findings contribute to our understanding of FAdV-2 and provide a basis for vaccine development.
Article
Agriculture, Dairy & Animal Science
Ebtsam Iraqi, Ali Abdel Hady, Nadia Elsayed, Hanaa Khalil, Amina El-Saadany, Karim El-Sabrout
Summary: Thermal manipulation during egg incubation, particularly at 12 to 18 days, has positive effects on embryonic development, hatching characteristics, chick quality, as well as posthatch thermotolerance and performance.
Article
Agriculture, Dairy & Animal Science
Yong Liu, Mingxin Song, He Bai, Chunhua Wang, Fei Wang, Qi Yuan
Summary: Dietary curcumin supplementation can significantly improve egg quality of quails in the late laying period, primarily by improving lipid metabolism and selectively regulating the intestinal microbial community.
Article
Agriculture, Dairy & Animal Science
Lei Zhang, Zhixuan Song, Peiyao Li, Xingju Song, Xinming Tang, Dandan Hu
Summary: This study evaluated the vaccine potential of recombinant proteins for avian coccidiosis caused by Eimeria. The results showed that the rEten5-B protein can trigger immune protection against E. tenella and may be a potential and effective subunit vaccine for the control of coccidiosis in poultry.
Article
Agriculture, Dairy & Animal Science
Milan Kumar Sharma, Amit Kumar Singh, Doyun Goo, Venkata Sesha Reddy Choppa, Hanseo Ko, Hanyi Shi, Woo Kyun Kim
Summary: The study investigates the effect of Eimeria infection on gastrointestinal physiology, growth performance, and egg production of Hy-Line W-36 laying hens during peak production. Results show that Eimeria infection negatively affects body weight, feed intake, immune response, and nutrient transporter gene expression. Egg production temporarily ceases in hens infected with high and medium-high dosages of Eimeria.
Article
Agriculture, Dairy & Animal Science
Elwy A. Ashour, Mahmoud Kamal, Hayman A. A. Altaie, Ayman A. Swelum, Gamaleldin M. Suliman, Guillermo Tellez-Isaias, Mohamed E. Abd El-Hack
Summary: This study evaluated the effects of CP and ME on the performance and nutritional value of Japanese quail lay chicken. The results showed that protein and energy levels significantly influenced all productive outcomes except feed conversion ratio. The combination of dietary energy and protein levels had a substantial effect on all egg quality trials evaluated. It is recommended to feed layer Japanese quail between the ages of 8 and 20 weeks during the summer with a dietary energy content of 2,900 kcal ME/kg and 20% CP.
Article
Agriculture, Dairy & Animal Science
J. E. Doornweerd, R. F. Veerkamp, B. de Klerk, M. van der Sluis, A. C. Bouwman, E. D. Ellen, G. Kootstra
Summary: Tracking group-housed individual broilers using video can provide valuable information on their health, welfare, and performance. This study conducted a comprehensive analysis on broiler tracking on video and potential tracking errors, highlighting the potential and challenges of phenotyping broiler locomotion. The results emphasized the importance of addressing tracking errors, potential algorithm improvements, and the need for an external animal identification system for efficient locomotion phenotyping.
Article
Agriculture, Dairy & Animal Science
Jiayu Wu, Yanan Wang, Yu An, Changyu Tian, Lingfeng Wang, Zuhong Liu, Desheng Qi
Summary: This study compared the gene expression differences in liver tissues of laying hens at different ages using RNA sequencing, and found that the transport and metabolism of amino acids changed during the growing period, which influenced the growth and development of the hens.
Article
Agriculture, Dairy & Animal Science
J. Raabe, G. Raveendran, W. Otten, K. Homeyer, T. Bartels
Summary: This study investigated the effects of different flicker frequencies on the behavior, performance, and stress response in male turkeys. The results showed that flicker frequencies of 165 Hz or higher had no detrimental effect on growth performance, injurious pecking, or endocrine stress response in the turkeys.
Article
Agriculture, Dairy & Animal Science
Adamu Mani Isa, Yanyan Sun, Yuanmei Wang, Yunlei Li, Jingwei Yuan, Aixin Ni, Hui Ma, Lei Shi, Hailai Hagos Tesfay, Yunhe Zong, Panlin Wang, Pingzhuang Ge, Jilan Chen
Summary: This study sequenced mRNAs and lncRNAs in the ovary stroma of specific chicken breeds and their reciprocal crossbreds to understand the molecular mechanism of heterosis for egg production. Results showed that genes with nonadditive expression were related to follicle growth and atresia as well as oxidative stress in the crossbred hens.
Article
Agriculture, Dairy & Animal Science
Zhepeng Wang, Qiu Chen, Yiwei Wang, Yulu Wang, Ruifang Liu
Summary: The study investigates the functional variants associated with chicken eggshell color in the SLCO1B3 gene by measuring the eggshell color of Lueyang black-boned chickens and analyzing the genetic data. It identifies 15 variants in SLCO1B3 that are significantly associated with eggshell color. However, the functional analysis shows that one specific variant, 1B3_SNP108, does not have a significant effect on promoter activity. This study highlights the importance of SLCO1B3 and its variants in breeding eggshell color.
Article
Agriculture, Dairy & Animal Science
P. Yin, Q. Tong, B. M. Li, W. C. Zheng, Y. Wang, H. Q. Peng, X. L. Xue, S. Q. Wei
Summary: This study investigated the welfare and health of laying hens in a multitier system. The results showed that the spatial distribution of hens changed with increasing age, and lower-ranking hens preferred to stay in lower tiers to avoid competition but still had access to resources. This improved the welfare and health of the hens near the end of the laying cycle.
Article
Agriculture, Dairy & Animal Science
Wenwen Liang, Siqiong Jie, Yiqin Wang, Xiaowei Wen, Yanling Xiong, Xiaoxi Lin, Zhengrong Lv
Summary: This study examined the effect of risk perceptions on preventive behavior among vendors in the live poultry wholesale market and the live poultry retail market in Guangdong Province using the health belief model and structural equation modeling. The results showed that perceived severity and perceived benefits positively influenced vendors' self-efficacy in the wholesale market, while perceived barriers negatively affected self-efficacy in both the wholesale and retail markets. Moreover, cues to action mediated the relationship between perceived severity, perceived benefits, and self-efficacy, and also mediated the effect of perceived susceptibility among wholesale market vendors.
Article
Agriculture, Dairy & Animal Science
Shreeya Sharma, Raveendra R. Kulkarni, Shayan Sharif, Hosni Hassan, Mohammadali Alizadeh, Scott Pratt, Khaled Abdelaziz
Summary: The study investigates the impact of exposing chick embryos to antigens via in ovo delivery of poultry-specific lactobacilli on the expression of genes associated with early bursal development and maturation. Results indicate that the supplementation of poultry-specific lactobacilli to chick embryos can accelerate the development and immunological maturation of the bursa of Fabricius.