Review
Chemistry, Analytical
Miguel Angel Aguirre, Antonio Canals
Summary: Magnetic deep eutectic solvents (MDESs) have been widely used in sample preparation, demonstrating their response to an external magnetic field. This review focuses on the application of MDESs in analytical chemistry, as well as the challenges and future prospects.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2022)
Review
Pharmacology & Pharmacy
Rahul G. Ingle, Su Zeng, Huidi Jiang, Wei-Jie Fang
Summary: Sample preparation is crucial in bioanalysis, but it faces challenges due to the unique characteristics of different biological matrices. Novel techniques have gained popularity in the past decade for their advantages in accuracy, automation, and convenience.
JOURNAL OF PHARMACEUTICAL ANALYSIS
(2022)
Review
Nutrition & Dietetics
Jorge A. M. Pereira, Natalia Casado, Priscilla Porto-Figueira, Jose S. Camara
Summary: This review focuses on the application of different microextraction approaches for the analysis of bioactive compounds in foods since 2015. Microextraction methods not only offer the opportunity to mitigate the environmental impact of organic solvents usage, but also improve lab equipment. Phenolics and alkaloids extraction from fruits, medicinal herbs, juices, and coffee using miniaturized formats of solid-phase extraction and liquid-liquid microextraction are the most popular applications. Furthermore, emergent sorbents based on carbon nanotubes and magnetic nanoparticles contribute to improving analytical limits.
FRONTIERS IN NUTRITION
(2022)
Review
Chemistry, Analytical
Sunkyung Jeong, Laszlo Hajba, Andras Guttman, Jiwoong Seol, Doo Soo Chung
Summary: Capillary electrophoresis (CE) is a powerful analytical technique for complex samples, but suffers from poor sensitivity and sample destacking. This review discusses the use of in-line solid-phase microextraction (SPME) and liquid-phase microextraction (LPME) techniques in CE, without the need for complex modifications to the commercial CE instrument. In-line coupling allows for reduced sample loss and increased enrichment factors, making it a valuable tool for analyzing trace substances in complex biological matrices.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2023)
Article
Engineering, Chemical
Jose S. Camara, Rosa Perestrelo, Basit Olayanju, Cristina Berenguer, Abuzar Kabir, Jorge A. M. Pereira
Summary: This review explores the different possibilities and applications of liquid phase-based microextraction techniques (LP mu ETs), including dispersive liquid-liquid microextraction, single-drop microextraction, hollow-fiber liquid-phase microextraction, and electro membrane extraction. These techniques are widely used in various fields such as environment, food and beverages, pharmaceutical, clinical, and forensic analysis.
Review
Chemistry, Analytical
Reham E. Kannouma, Mohamed A. Hammad, Amira H. Kamal, Fotouh R. Mansour
Summary: Liquid-phase microextraction (LPME) is an important technique for sample preparation that is widely used to extract various organic, inorganic, and pharmaceutical compounds from different environmental and biological matrices. LPME has three configurations - single drop microextraction, hollow-fiber liquid-phase microextraction, and dispersive liquid-liquid microextraction - each with different applications and advantages.
MICROCHEMICAL JOURNAL
(2022)
Review
Chemistry, Analytical
Rajeev Jain, Noorfatimah Yahaya, Ahmad Husaini Mohamed, Abuzar Kabir, Lalit Pratap Chandrawanshi, Mohamed AbdElrahman, Mohammed M. Ghoneim, Shankar M. Bakkannavar
Summary: The analysis of drugs and toxicants in postmortem samples is complex, but green sample preparation techniques provide efficient and eco-friendly alternatives. This review discusses various green sample preparation approaches and highlights future directions in postmortem toxicology.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2023)
Review
Chemistry, Analytical
Ebaa Adnan Azooz, Mustafa Tuzen, Wael Mortada, Naeem Ullah
Summary: This review summarizes the application of different extraction methods for selenium extraction and determination, including microextraction, solid-phase extraction, and liquid-phase microextraction. It also discusses the use of different dispersive media to enhance selenium separation and the application of environmentally friendly solvents. Additionally, it provides a summary of cheap, simple, and accurate techniques that have not yet been used.
CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY
(2022)
Review
Chemistry, Analytical
Muhammad Saqaf Jagirani, Ozgur Ozalp, Mustafa Soylak
Summary: This review focuses on green microextraction methods for pesticide extraction from environmental and food samples. It emphasizes that the success of microextraction lies in its simplicity, environmental friendliness, and applications, with studies showing significant advantages over conventional methods. The future development and application of microextraction techniques are promising with continued attention and resources from the analytical community.
CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY
(2022)
Review
Chemistry, Analytical
Reyhaneh Nayebi, Farzaneh Shemirani
Summary: The advancement of smart materials, like ferrofluids, has greatly impacted sample preparation techniques. Ferrofluids, being liquid and magnetically controllable, have attracted attention for their role in separating analytes and facilitating recovery. While ferrofluid-based microextraction techniques offer precise positioning and recovery benefits, challenges and future prospects are also present.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Zhengxin Li, Hongyan Wu, Jae Bem You, Xiaomeng Wang, Hongbo Zeng, Detlef Lohse, Xuehua Zhang
Summary: Liquid-liquid extraction based on surface nanodroplets is a green and sustainable technique used to extract and concentrate analytes from a sample flow. However, only a few in situ analytical techniques are applicable for online detection and analysis based on nanodroplet extraction. In this study, the versatility of surface nanodroplet-based extraction was demonstrated, and the collected surface droplets were successfully analyzed using offline analytical techniques. The technique showed potential for streamlining the process of sample pretreatment for sensitive chemical detection and quantification using common analytic tools.
Review
Chemistry, Analytical
Ali Pourali, Aysa Abbasalizadeh, Mohammad Reza Afshar Mogaddam, Mir Ali Farajzadeh, Mustafa Tuzen, Mahboob Nemati
Summary: Liquid phase microextraction techniques are a miniaturized version of traditional liquid-liquid extraction, using only a small amount of solvent to extract analytes from a sample. They have been widely applied in the analysis of various analytes in food, pharmaceuticals, and beverages. This review focuses on the application of these techniques in dairy products and discusses the advantages and disadvantages of different liquid phase microextraction methods.
CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY
(2023)
Review
Food Science & Technology
Fernanda C. O. L. Martins, Alex D. Batista, Wanessa R. Melchert
Summary: This review discusses the classification, chemical structure, use, and toxicology of carbamates and dithiocarbamates, two classes of pesticides widely used in agriculture. It also explores the evolution of liquid- and solid-phase microextractions for extracting these pesticides in water and food samples, and their application in green analytical chemistry.
COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY
(2021)
Article
Biochemical Research Methods
Mohammed Altahir Suliman, Taofiq Abdulraheem Olarewaju, Chanbasha Basheer, Hian Kee Lee
Summary: Petroleum is a complex material containing a wide range of compounds, and ASTM methods are globally accepted but have limitations in terms of sample preparation. The challenge in petrochemical analysis is to develop rapid and simpler automated sample preparation procedures. Microextraction is considered an excellent complement to current methods.
JOURNAL OF CHROMATOGRAPHY A
(2021)
Review
Chemistry, Analytical
Muhammed Saqaf Jagirani, Mustafa Soylak
Summary: Food chemistry is the study of food quality and origin, focusing on the detection and identification of contaminants to ensure food safety and improve analytical methods. Microextraction has gained attention due to its low consumption, easy operation, and environmental friendliness.
CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
A. Y. Simao, P. Oliveira, L. M. Rosendo, T. Rosado, M. Andraus, M. Barroso, E. Gallardo
Summary: This article presents the development and validation of a simple and cost-effective method for detecting ketamine and its main metabolite in hair samples. The method is characterized by low organic solvent usage, high selectivity, accuracy, and suitability for routine analysis.
JOURNAL OF ANALYTICAL TOXICOLOGY
(2023)
Article
Biochemical Research Methods
Sara Julio, Raquel A. Ferro, Susana Santos, Andrea Alexandre, Maria Joao Caldeira, Joao Franco, Mario Barroso, Helena Gaspar
Summary: Synthetic cathinones have become an important class of new psychoactive substances in the past 15 years, posing a serious threat to public health and challenges to forensic laboratories. This study aimed to synthesize emerging cathinones and develop an analytical method for their accurate determination in forensic situations. The results show that this method is selective, precise, and accurate, allowing the detection of these compounds even at low concentrations.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2023)
Article
Obstetrics & Gynecology
E. Nunes, E. Gallardo, S. Morgado-Nunes, J. Fonseca-Moutinho
Summary: This study aimed to assess the association between steroid hormone levels and sexual function in postmenopausal women. The main finding was the association of androstenedione with sexual function in postmenopausal women.
Article
Biochemistry & Molecular Biology
Joao Batista-Silva, Diana Gomes, Jorge Barroca-Ferreira, Eugenia Gallardo, Angela Sousa, Luis A. Passarinha
Summary: This work demonstrates the potential of calcium- and nickel-crosslinked Gellan Gum (GG) microspheres to capture STEAP1 directly from complex lysates in a batch method. The calcium-crosslinked microspheres were applied in an ionic exchange strategy, while the nickel-crosslinked microspheres were applied in an affinity strategy. Both formulations showed small diameters, but the calcium-crosslinked microspheres were smoother. The most promising results were obtained for the ionic strategy, where calcium-crosslinked GG microspheres were able to completely bind DM-solubilized STEAP1 in lysate samples.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Obstetrics & Gynecology
Elsa Nunes, Eugenia Gallardo, Sara Morgado-Nunes, Jose Fonseca-Moutinho
Summary: This study investigates the effect of postmenopausal bilateral oophorectomy on plasma steroid hormone levels. The results demonstrate significantly lower levels of DHEA and oestradiol in the group with bilateral salpingo-oophorectomy compared to the group with isolated hysterectomy. These findings suggest significant endocrine activity of the postmenopausal ovary.
JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2023)
Review
Engineering, Chemical
Luana M. Rosendo, Ana Teresa Brinca, Bruno Pires, Goncalo Catarro, Tiago Rosado, Raquel P. F. Guine, Andre R. T. S. Araujo, Ofelia Anjos, Eugenia Gallardo
Summary: Natural products are widely used in industry, food, and therapy. Characterizing them chemically is vital to explore their potential applications. Microextraction techniques, which use less organic solvents and sample amount compared to classical techniques, have gained popularity but are still less used in natural product analysis. This manuscript reviews popular solid-based miniaturized sample preparation techniques and discusses their advantages, disadvantages, and main applications in determining compounds in natural products.
Article
Biochemistry & Molecular Biology
Carina Gameiro, Joana Goncalves, Sofia Soares, Tiago Rosado, Andre R. T. S. Araujo, Luis A. Passarinha, Mario Barroso, Eugenia Gallardo
Summary: This study evaluates the stability of antipsychotics chlorpromazine, levomepromazine, cyamemazine, clozapine, haloperidol, and quetiapine in oral fluid samples. The stability of these drugs in biological fluids is crucial as they have narrow therapeutic windows and monitoring is important.
Review
Pharmacology & Pharmacy
Sofia Soares, Tiago Rosado, Mario Barroso, Eugenia Gallardo
Summary: Therapeutic drug monitoring is important for drugs with narrow therapeutic windows, as drug concentrations in biological fluids are used for therapy individualization and adherence assessment. Monitoring these drugs is crucial to minimize medical interactions and toxic effects. The development of new monitoring methodologies, such as fabric-phase extractions, is of great interest in this field. This paper aims to critically review solid-phase microextraction techniques for drug detection in therapeutic monitoring situations.
Editorial Material
Biochemical Research Methods
Eugenia Gallardo, Tiago Rosado, Mario Barroso
Article
Plant Sciences
Soraia I. Pedro, Tiago A. Fernandes, Angelo Luis, Alexandra M. M. Antunes, Jose C. Goncalves, Jorge Gominho, Eugenia Gallardo, Ofelia Anjos
Summary: This study evaluated the potential industrial applications of various Acacia species by examining their chemical composition, antioxidant, and antimicrobial properties. Among the studied species, A. pycnantha exhibited a higher concentration of total phenolic compounds and displayed notable antibacterial activity. Vibrational spectroscopy was a reliable method for distinguishing between species.
Review
Plant Sciences
Joana Goncalves, Angelo Luis, Eugenia Gallardo, Ana Paula Duarte
Summary: Traditional therapies using plants have gained popularity due to economic motives and preference for natural treatments. Ayahuasca, according to studies, may offer beneficial effects in treating physical and psychological imbalances. This systematic review of studies published until December 2022 found 66 publications supporting the therapeutic potential of ayahuasca in conditions like depression, anxiety, neurobiological diseases, inflammation, and microbial infections.
Review
Biology
Bruno Pires, Luana M. Rosendo, Ana Teresa Brinca, Ana Y. Simao, Mario Barroso, Tiago Rosado, Eugenia Gallardo
Summary: This review discusses the potential therapeutic applications of amphetamine-type stimulants in various psychiatric disorders and highlights their associated risks and benefits. These compounds offer promising avenues for treatment, but further research is necessary.
