Development of functional polyplex micelles for systemic gene therapy

Targeted gene delivery by polyplex micelles with crowded PEG palisade and cRGD moiety for systemic treatment of pancreatic tumors

(2014) Zhishen Ge et al.   BIOMATERIALS

Precision Templating with DNA of a Virus-like Particle with Peptide Nanostructures

(2013) Yves Ruff et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Tethered PEG Crowdedness Determining Shape and Blood Circulation Profile of Polyplex Micelle Gene Carriers

(2013) Theofilus A. Tockary et al.   MACROMOLECULES

Polymer–drug conjugates: Origins, progress to date and future directions

(2012) Jindřich Kopeček   ADVANCED DRUG DELIVERY REVIEWS

The EPR effect for macromolecular drug delivery to solid tumors: Improvement of tumor uptake, lowering of systemic toxicity, and distinct tumor imaging in vivo

(2012) Hiroshi Maeda et al.   ADVANCED DRUG DELIVERY REVIEWS

Plasmid-Templated Shape Control of Condensed DNA-Block Copolymer Nanoparticles

(2012) Xuan Jiang et al.   ADVANCED MATERIALS

Bioactive Polymeric Metallosomes Self-Assembled through Block Copolymer–Metal Complexation

(2012) Kensuke Osada et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

In Vivo Gene Delivery by Nonviral Vectors: Overcoming Hurdles?

(2012) Yuan Zhang et al.   MOLECULAR THERAPY

Polycation-siRNA nanoparticles can disassemble at the kidney glomerular basement membrane

(2012) J. E. Zuckerman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nanomaterials for Drug Delivery

(2012) J. A. Hubbell et al.   SCIENCE

Supramolecular Nanodevices: From Design Validation to Theranostic Nanomedicine

(2011) Horacio Cabral et al.   ACCOUNTS OF CHEMICAL RESEARCH

Systemic delivery of siRNA to tumors using a lipid nanoparticle containing a tumor-specific cleavable PEG-lipid

(2011) Hiroto Hatakeyama et al.   BIOMATERIALS

Enhanced gene expression promoted by the quantized folding of pDNA within polyplex micelles

(2011) Kensuke Osada et al.   BIOMATERIALS

Effect of integrin targeting and PEG shielding on polyplex micelle internalization studied by live-cell imaging

(2011) F.M. Mickler et al.   JOURNAL OF CONTROLLED RELEASE

Odd–Even Effect of Repeating Aminoethylene Units in the Side Chain of N-Substituted Polyaspartamides on Gene Transfection Profiles

(2011) Hirokuni Uchida et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nanoparticle PEGylation for imaging and therapy

(2011) Jesse V Jokerst et al.   Nanomedicine

Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size

(2011) H. Cabral et al.   Nature Nanotechnology

State-of-the-art gene-based therapies: the road ahead

(2011) Mark A. Kay   NATURE REVIEWS GENETICS

Biodegradable polyamino acid-based polycations as safe and effective gene carrier minimizing cumulative toxicity

(2010) Keiji Itaka et al.   BIOMATERIALS

Polyplex micelles prepared from ω-cholesteryl PEG-polycation block copolymers for systemic gene delivery

(2010) Makoto Oba et al.   BIOMATERIALS

Polyplex nanomicelle promotes hydrodynamic gene introduction to skeletal muscle

(2010) Keiji Itaka et al.   JOURNAL OF CONTROLLED RELEASE

Stealth nanoparticles: High density but sheddable PEG is a key for tumor targeting

(2010) Shyh-Dar Li et al.   JOURNAL OF CONTROLLED RELEASE

Antibody derivatization and conjugation strategies: Application in preparation of stealth immunoliposome to target chemotherapeutics to tumor

(2010) Arehalli S. Manjappa et al.   JOURNAL OF CONTROLLED RELEASE

Quantized Folding of Plasmid DNA Condensed with Block Catiomer into Characteristic Rod Structures Promoting Transgene Efficacy

(2010) Kensuke Osada et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Antiangiogenic Gene Therapy of Solid Tumor by Systemic Injection of Polyplex Micelles Loading Plasmid DNA Encoding Soluble Flt-1

(2010) Makoto Oba et al.   MOLECULAR PHARMACEUTICS

Nanoparticles Targeted With NGR Motif Deliver c-myc siRNA and Doxorubicin for Anticancer Therapy

(2010) Yunching Chen et al.   MOLECULAR THERAPY

Intracellulartransduction using cell-penetrating peptides

(2009) Rupa Sawant et al.   Molecular BioSystems

Polyplexes from Poly(aspartamide) Bearing 1,2-Diaminoethane Side Chains Induce pH-Selective, Endosomal Membrane Destabilization with Amplified Transfection and Negligible Cytotoxicity

(2008) Kanjiro Miyata et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

PEG-Detachable Polyplex Micelles Based on Disulfide-Linked Block Catiomers as Bioresponsive Nonviral Gene Vectors

(2008) Seiji Takae et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Polyplex Micelles with Cyclic RGD Peptide Ligands and Disulfide Cross-Links Directing to the Enhanced Transfection via Controlled Intracellular Trafficking

(2008) Makoto Oba et al.   MOLECULAR PHARMACEUTICS