Article
Polymer Science
Deniz Coban, Olga Gridina, Matthias Karg, Andre H. Groeschel
Summary: This study describes design rules for controlling the morphology of multicompartment micelles (MCMs) in water and proposes a method to predict the final MCM shape based on the molar ratio of PEO to PMA.
Article
Polymer Science
Theiophile Pelras, Andras Eisenga, Gabor Ersek, Aldo Altomare, Giuseppe Portale, Marleen Kamperman, Katja Loos
Summary: Despite advancements in polymerization techniques, the synthesis of functional macromolecules can still be time-consuming, especially when incompatible chemistries are involved. In this study, one-pot synthesis of strong anionic/charge-neutral block copolymers is explored using a three-step process involving macroinitiator synthesis, chain extension through photomediated atom transfer radical polymerization, and in situ deprotection. The resulting block copolymers exhibit self-assembly properties in aqueous media and can be produced easily, demonstrating versatility in producing strong polymer amphiphiles.
Article
Polymer Science
Puja Das Karmakar, Sagar Pal
Summary: In this study, a new pH-responsive amphiphilic graft copolymer was synthesized using ROP and RAFT techniques. The copolymer can efficiently self-assemble into micelles and is suitable for delivering drugs as a nanocarrier.
Article
Polymer Science
Huiying Wang, Qiang Chen, Zhen Geng, Jingyi Rao, Bijin Xiong, Frederic Lortie, Julien Bernard, Wolfgang H. Binder, Senbin Chen, Jintao Zhu
Summary: By introducing 2,6-diaminopyridine moieties and H-bonding amphiphilic interactions, a simple and effective self-assembly strategy was designed to form giant vesicles with a diameter of approximately 3 μm, providing a new opportunity for the design of supramolecular polymers.
Article
Polymer Science
Yucheng Zhang, Atsushi Takahara
Summary: Amphiphilic copolymers containing superhydrophobic and superhydrophilic segments were designed and synthesized, showing different molecular aggregation structures and thermal stability. The polymeric film of P(FA-C-8-ran-MAPS) exhibited strong oleophobicity under both air and water conditions.
Article
Polymer Science
Izabela Zaborniak, Natalia Pienkowska, Pawel Chmielarz, Grzegorz Bartosz, Andrzej Dziedzic, Izabela Sadowska-Bartosz
Summary: Nitroxide-containing amphiphilic polymers were synthesized using a simplified electrochemically mediated atom transfer radical polymerization (seATRP). The prepared polymers self-assembled into micelles in aqueous solution and exhibited biocompatibility and antioxidant effects, making them potential candidates for in vivo applications.
Article
Chemistry, Multidisciplinary
Shannon M. North, Steven P. Armes
Summary: In this study, zwitterionic diblock copolymers were successfully synthesized using RAFT polymerization in a wholly aqueous environment, with the isoelectric point in aqueous solution tunable by varying monomer proportions. These copolymers show promise for potential applications.
Article
Engineering, Chemical
Karell Bosson, Pierre Marcasuzaa, Antoine Bousquet, Guenter E. M. Tovar, Vladimir Atanasov, Laurent Billon
Summary: Sulfonated block copolymers and statistical copolymers were synthesized for proton exchange membrane water electrolyser applications. These polymers demonstrated self-assembly, improved mechanical properties, and conductivity. The findings are important for developing efficient membrane materials.
JOURNAL OF MEMBRANE SCIENCE
(2022)
Article
Polymer Science
Chulu Zhou, Cuiping Hou, Lijie Wang, Wei Chen, Jianhua Cheng
Summary: In this study, norbornene macromonomers with PS or PtBA side chains were synthesized using a combination of ATRP and click reactions. The resulting linear and star-shaped brush block copolymers showed the ability to self-assemble into spherical micelles in solution. Interestingly, star diblock copolymers exhibited more stable properties compared to linear analogues, with less sensitivity to changes in composition.
Article
Polymer Science
Lenka Loukotova, Pavel Svec, Ondrej Groborz, Tomas Heizer, Hynek Benes, Helena Raabova, Tereza Belinova, Vit Herynek, Martin Hruby
Summary: This study compared the potential and properties of amphiphilic gradient and block copolymers in drug delivery systems, finding that gradient copolymers have broader glass transition intervals and higher drug loading capacities.
Article
Polymer Science
Daniela de Morais Zanata, Maria Isabel Felisberti
Summary: In this study, thermo-responsive and pH-responsive triblock copolymers were synthesized, which can self-assemble into nanostructures and encapsulate hydrophobic molecules under specific conditions. The P4VP blocks can coordinate with Cu2+ to form a thermo- and pH-responsive nanogel, achieving size reduction through thermo- or pH-induced deswelling.
Article
Polymer Science
Sandra E. Smeltzer, Connor A. Sanders, Yang Liu, Sean R. George, Crispin Amiri, Andreas Gernandt, Bernd Reck, Michael F. Cunningham
Summary: This study investigated the aqueous solution and aggregation behavior of polystyrene-b-poly[styrene-r-(acrylic acid)] block-random copolymers. The materials showed better dispersion in water compared to polystyrene-b-poly(acrylic acid) block copolymers of similar molecular weight and composition. The self-assembly of these materials into multichain aggregates rather than self-folding behavior was observed. Caution must be used when interpreting particle size data from dynamic light scattering with polyelectrolyte solutions, and other characterization methods should be used to confirm findings. The understanding of block-random copolymer solution properties enables their wide application in fields such as biomedicine, catalysis, and stabilizers in emulsion polymerization.
Article
Polymer Science
Shin Inagaki, Tomoya Higashihara
Summary: A novel ABC-type triblock copolymer, consisting of PMMA, P3HT, and PS, was synthesized by the bilateral CuAAC reaction, resulting in a high yield.
Article
Nanoscience & Nanotechnology
Yuxiu You, Fanggang Li, Yan Ai, Facai Wei, Jing Cui, Jianwei Fu, Maojun Zheng, Shaohua Liu
Summary: A rationally designed strategy was developed to synthesize hierarchically porous Fe-based metal-organic frameworks (P-Fe-MOF) via solution-based self-assembly of diblock copolymers, which showed promising application potential in the field of supercapacitors.
Article
Polymer Science
Hong Zhai, Kaibin Chen, Yue Meng, Zejia Wu, Rongli Deng, Ying Bai, Jing Zhou, Daping Quan
Summary: A diblock polycarbonate with tunable block length and active sites is synthesized via one-pot sequential ring-opening polymerization. The versatile copolymer can self-assemble into micro particles with different morphology and surface charge, and further aggregate into multi-compartment vesicles. These amphiphilic polycarbonates have great potential in biomedical applications.
Article
Polymer Science
Paige A. Shaw, Maxime Klausen, Mark Bradley
Summary: A light-responsive polymer capable of controlled release of camptothecin and generation of reactive oxygen species (ROS) was developed, which exhibited high cancer cell killing activity through both camptothecin release and ROS generation.
Article
Polymer Science
Donghui Zhang, Shiqi Liu, Zhihao Cai, Weizhe Luo, Guojian Liu, Runhui Liu
Summary: A straightforward and efficient method for synthesizing NPC monomers has been developed in this study, which enhances the availability of NPC monomers and facilitates the synthesis of polypeptides.
