FDA-approved poly(ethylene glycol)–protein conjugate drugs

Emerging synthetic approaches for protein–polymer conjugations

(2011) Rebecca M. Broyer et al.   CHEMICAL COMMUNICATIONS

Poly(ethylene glycol) in Drug Delivery: Pros and Cons as Well as Potential Alternatives

(2010) Katrin Knop et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

In Situ Growth of Side-Chain PEG Polymers from Functionalized Human Growth Hormone—A New Technique for Preparation of Enhanced Protein−Polymer Conjugates

(2010) Johannes Pall Magnusson et al.   BIOCONJUGATE CHEMISTRY

Protein–polymer conjugates: synthetic approaches by controlled radical polymerizations and interesting applications

(2010) Gregory N Grover et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Improvement of Drug Therapy by Covalent PEG Conjugation: An Overview From a Research Laboratory

(2010) Gianfranco Pasut et al.   ISRAEL JOURNAL OF CHEMISTRY

Beyond the Canonical 20 Amino Acids: Expanding the Genetic Lexicon

(2010) Travis S. Young et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pegloticase

(2010) Naomi Schlesinger et al.   NATURE REVIEWS DRUG DISCOVERY

Recent advances in the design of bioconjugates from controlled/living radical polymerization

(2010) Benjamin Le Droumaguet et al.   Polymer Chemistry

In situ growth of a PEG-like polymer from the C terminus of an intein fusion protein improves pharmacokinetics and tumor accumulation

(2010) W. Gao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Toward Living Radical Polymerization

(2008) Graeme Moad et al.   ACCOUNTS OF CHEMICAL RESEARCH

Native protein-initiated ATRP: A viable and potentially superior alternative to PEGylation for stabilizing biologics

(2008) Virginia Depp et al.   Acta Biomaterialia

Reduction of plasma urate levels following treatment with multiple doses of pegloticase (polyethylene glycol-conjugated uricase) in patients with treatment-failure gout: Results of a phase II randomized study

(2008) John S. Sundy et al.   ARTHRITIS AND RHEUMATISM

The Impact of PEGylation on Biological Therapies

(2008) Francesco M Veronese et al.   BIODRUGS

Peptide/protein–polymer conjugates: synthetic strategies and design concepts

(2008) Marc A. Gauthier et al.   CHEMICAL COMMUNICATIONS

The Pharmacology of PEGylation: Balancing PD with PK to Generate Novel Therapeutics

(2008) C.Simone Fishburn   JOURNAL OF PHARMACEUTICAL SCIENCES

Optimization of a Biomimetic Transamination Reaction

(2008) Rebecca A. Scheck et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

PEG-uricase in the management of treatment-resistant gout and hyperuricemia

(2007) Merry R. Sherman et al.   ADVANCED DRUG DELIVERY REVIEWS

Radical addition–fragmentation chemistry in polymer synthesis

(2007) Graeme Moad et al.   POLYMER