Overcoming the PEG-addiction: well-defined alternatives to PEG, from structure–property relationships to better defined therapeutics
出版年份 2011 全文链接
标题
Overcoming the PEG-addiction: well-defined alternatives to PEG, from structure–property relationships to better defined therapeutics
作者
关键词
-
出版物
Polymer Chemistry
Volume 2, Issue 9, Pages 1900
出版商
Royal Society of Chemistry (RSC)
发表日期
2011-03-28
DOI
10.1039/c0py00406e
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Stabilization of Virus-like Particles with Poly(2-oxazoline)s
- (2011) Florian Manzenrieder et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- HPMA Based Amphiphilic Copolymers Mediate Central Nervous Effects of Domperidone
- (2011) Mirjam Hemmelmann et al. MACROMOLECULAR RAPID COMMUNICATIONS
- Molecular imaging of HPMA copolymers: Visualizing drug delivery in cell, mouse and man☆
- (2010) Zheng-Rong Lu ADVANCED DRUG DELIVERY REVIEWS
- Tailored Design of Au Nanoparticle-siRNA Carriers Utilizing Reversible Addition−Fragmentation Chain Transfer Polymers∥
- (2010) Stacey Kirkland-York et al. BIOMACROMOLECULES
- In Vitro Cytotoxicity of RAFT Polymers
- (2010) Dakrong Pissuwan et al. BIOMACROMOLECULES
- Backbone Degradable MultiblockN-(2-Hydroxypropyl)methacrylamide Copolymer Conjugates via Reversible Addition−Fragmentation Chain Transfer Polymerization and Thiol−ene Coupling Reaction
- (2010) Huaizhong Pan et al. BIOMACROMOLECULES
- Doubly amphiphilic poly(2-oxazoline)s as high-capacity delivery systems for hydrophobic drugs
- (2010) Robert Luxenhofer et al. BIOMATERIALS
- Structure-biocompatibility relationship of dendritic polyglycerol derivatives
- (2010) Jayant Khandare et al. BIOMATERIALS
- Building nanostructures using RAFT polymerization
- (2010) Cyrille Boyer et al. JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY
- Modification of Polysaccharides Through Controlled/Living Radical Polymerization Grafting-Towards the Generation of High Performance Hybrids
- (2010) Morgan Tizzotti et al. MACROMOLECULAR RAPID COMMUNICATIONS
- Ordered Chiral Structures in the Crystals of Main-Chain Chiral Poly(2-oxazoline)s
- (2010) Meta M. Bloksma et al. MACROMOLECULES
- Reduced Skin Photosensitivity withmeta-Tetra(hydroxyphenyl)chlorin-Loaded Micelles Based on a Poly(2-ethyl-2-oxazoline)-b-poly(d,l-lactide) Diblock Copolymer in Vivo
- (2010) Ming-Jium Shieh et al. MOLECULAR PHARMACEUTICS
- Protein Modification with Amphiphilic Block Copoly(2-oxazoline)s as a New Platform for Enhanced Cellular Delivery
- (2010) Jing Tong et al. MOLECULAR PHARMACEUTICS
- A Novel Poly(l-glutamic acid) Dendrimer Based Drug Delivery System with Both pH-Sensitive and Targeting Functions
- (2010) Hui Yuan et al. MOLECULAR PHARMACEUTICS
- Polymer–drug conjugates for novel molecular targets
- (2010) Joaquin Sanchis et al. Nanomedicine
- Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles
- (2010) Mark E. Davis et al. NATURE
- Strategies in the design of nanoparticles for therapeutic applications
- (2010) Robby A. Petros et al. NATURE REVIEWS DRUG DISCOVERY
- Synthesis of glycopolymers and their multivalent recognitions with lectins
- (2010) S. R. Simon Ting et al. Polymer Chemistry
- Recent advances in the design of bioconjugates from controlled/living radical polymerization
- (2010) Benjamin Le Droumaguet et al. Polymer Chemistry
- Polymer–protein conjugates: an enzymatic activity perspective
- (2010) Marc A. Gauthier et al. Polymer Chemistry
- Main-chain chiral copoly(2-oxazoline)s
- (2010) Meta M. Bloksma et al. Polymer Chemistry
- Poly(ethylene glycol) as a sensitive regulator of cell survival fate on polymeric biomaterials: the interplay of cell adhesion and pro-oxidant signaling mechanisms
- (2010) Hak-Joon Sung et al. Soft Matter
- Secondary structure formation of main-chain chiral poly(2-oxazoline)s in solution
- (2010) Meta M. Bloksma et al. Soft Matter
- Short interfering RNA-mediated gene silencing; towards successful application in human patients
- (2009) Mikiko C. Siomi ADVANCED DRUG DELIVERY REVIEWS
- Towards therapeutic application of RNA-mediated gene regulation
- (2009) Yoshinobu Takakura ADVANCED DRUG DELIVERY REVIEWS
- PEG conjugates in clinical development or use as anticancer agents: An overview
- (2009) Gianfranco Pasut et al. ADVANCED DRUG DELIVERY REVIEWS
- HPMA copolymers: 30years of advances☆
- (2009) Twan Lammers et al. ADVANCED DRUG DELIVERY REVIEWS
- Structural and chemical aspects of HPMA copolymers as drug carriers☆
- (2009) Karel Ulbrich et al. ADVANCED DRUG DELIVERY REVIEWS
- Immunogenicity and immunomodulatory properties of HPMA-based polymers☆
- (2009) Blanka Říhová et al. ADVANCED DRUG DELIVERY REVIEWS
- Improving the efficacy of combined modality anticancer therapy using HPMA copolymer-based nanomedicine formulations☆
- (2009) Twan Lammers ADVANCED DRUG DELIVERY REVIEWS
- HPMA copolymers: Origins, early developments, present, and future☆
- (2009) Jindřich Kopeček et al. ADVANCED DRUG DELIVERY REVIEWS
- Micelles based on HPMA copolymers☆
- (2009) M. Talelli et al. ADVANCED DRUG DELIVERY REVIEWS
- Do HPMA copolymer conjugates have a future as clinically useful nanomedicines? A critical overview of current status and future opportunities☆
- (2009) Ruth Duncan et al. ADVANCED DRUG DELIVERY REVIEWS
- Sulfated and Non-Sulfated Glycopeptide Recognition Domains of P-Selectin Glycoprotein Ligand 1 and their Binding to P- and E-Selectin
- (2009) Katharina Baumann et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Poly(2-oxazoline)s: A Polymer Class with Numerous Potential Applications
- (2009) Richard Hoogenboom ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Impact of Molecular Weight in Four-Branched Star Vectors with Narrow Molecular Weight Distribution on Gene Delivery Efficiency
- (2009) Yasushi Nemoto et al. BIOCONJUGATE CHEMISTRY
- RAFT Synthesis and Stimulus-Induced Self-Assembly in Water of Copolymers Based on the Biocompatible Monomer 2-(Methacryloyloxy)ethyl Phosphorylcholine
- (2009) Bing Yu et al. BIOMACROMOLECULES
- Intracellular Trafficking and Subcellular Distribution of a Large Array of HPMA Copolymers
- (2009) Jon Callahan et al. BIOMACROMOLECULES
- Radioactive Labeling of Defined HPMA-Based Polymeric Structures Using [18F]FETos for In Vivo Imaging by Positron Emission Tomography
- (2009) Matthias M. Herth et al. BIOMACROMOLECULES
- Interaction of Nanoparticles with Cells
- (2009) Volker Mailänder et al. BIOMACROMOLECULES
- Characterization of Tailor-Made Copolymers of Oligo(ethylene glycol) Methyl Ether Methacrylate andN,N-Dimethylaminoethyl Methacrylate as Nonviral Gene Transfer Agents: Influence of Macromolecular Structure on Gene Vector Particle Properties and Transfection Efficiency
- (2009) Senta Üzgün et al. BIOMACROMOLECULES
- Near-infrared fluorescence tumor imaging using nanocarrier composed of poly(l-lactic acid)-block-poly(sarcosine) amphiphilic polydepsipeptide
- (2009) Akira Makino et al. BIOMATERIALS
- The uptake of N-(2-hydroxypropyl)-methacrylamide based homo, random and block copolymers by human multi-drug resistant breast adenocarcinoma cells
- (2009) Matthias Barz et al. BIOMATERIALS
- Development of polyion complex micelles for encapsulating and delivering amphotericin B
- (2009) Chau-Hui Wang et al. BIOMATERIALS
- The exploitation of differential endocytic pathways in normal and tumor cells in the selective targeting of nanoparticulate chemotherapeutic agents
- (2009) Gaurav Sahay et al. BIOMATERIALS
- The use of PEGylated poly [2-(N,N-dimethylamino) ethyl methacrylate] as a mucosal DNA delivery vector and the activation of innate immunity and improvement of HIV-1-specific immune responses
- (2009) Yong Qiao et al. BIOMATERIALS
- The utilization of pathogen-like cellular trafficking by single chain block copolymer
- (2009) Gaurav Sahay et al. BIOMATERIALS
- Preclinical and clinical studies of anticancer agent-incorporating polymer micelles
- (2009) Yasuhiro Matsumura et al. CANCER SCIENCE
- Differences in cytotoxicity of poly(PEGA)s synthesized by reversible addition–fragmentation chain transfer polymerization
- (2009) Chien-Wen Chang et al. CHEMICAL COMMUNICATIONS
- One- pot synthesis and biofunctionalization of glycopolymers via RAFT polymerization and thiol–ene reactions
- (2009) Cyrille Boyer et al. CHEMICAL COMMUNICATIONS
- Synthesis of Well-Defined Polypeptide-Based Materials via the Ring-Opening Polymerization of α-Amino AcidN-Carboxyanhydrides
- (2009) Nikos Hadjichristidis et al. CHEMICAL REVIEWS
- Bioapplications of RAFT Polymerization
- (2009) Cyrille Boyer et al. CHEMICAL REVIEWS
- Polyoxazoline-based Crystalline Microspheres for Carbohydrate-Protein Recognition
- (2009) Christina Diehl et al. CHEMISTRY-A EUROPEAN JOURNAL
- Preparation of synthetic polyoxazoline based carrier and Vibrio cholerae O-specific polysaccharide conjugate vaccine
- (2009) Pavol Farkaš et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Conjugation of salmon calcitonin to a combed-shaped end functionalized poly(poly(ethylene glycol) methyl ether methacrylate) yields a bioactive stable conjugate
- (2009) Sinéad M. Ryan et al. JOURNAL OF CONTROLLED RELEASE
- One-pot controlled synthesis of biodegradable and biocompatible co-polymer micelles
- (2009) Aram Omer Saeed et al. JOURNAL OF MATERIALS CHEMISTRY
- Synthesis and bioimmunological efficiency of poly(2-oxazolines) containing a free amino group
- (2009) J. Kronek et al. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
- Modification of RAFT-polymers via thiol-ene reactions: A general route to functional polymers and new architectures
- (2009) Cyrille Boyer et al. JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY
- Synthesis of dendritic carbohydrate end-functional polymers via RAFT: Versatile multi-functional precursors for bioconjugations
- (2009) Jiangtao Xu et al. JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY
- Postpolymerization modification of poly(pentafluorophenyl methacrylate): Synthesis of a diverse water-soluble polymer library
- (2009) Matthew I. Gibson et al. JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY
- Cyclic polymers: Synthetic strategies and physical properties
- (2009) Hans R. Kricheldorf JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY
- One-Pot Synthesis of Brush-Like Polymers via Integrated Ring-Opening Metathesis Polymerization and Polymerization of Amino AcidN-Carboxyanhydrides
- (2009) Hua Lu et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Cyclic Poly(α-peptoid)s and Their Block Copolymers from N-Heterocyclic Carbene-Mediated Ring-Opening Polymerizations of N-SubstitutedN-Carboxylanhydrides
- (2009) Li Guo et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Polymer-Peptide Block Copolymers - An Overview and Assessment of Synthesis Methods
- (2009) Hana Robson Marsden et al. MACROMOLECULAR BIOSCIENCE
- Amphiphilic Copolymer Membranes Promote NADH:Ubiquinone Oxidoreductase Activity: Towards an Electron-Transfer Nanodevice
- (2009) Alexandra Graff et al. MACROMOLECULAR CHEMISTRY AND PHYSICS
- Efficient Usage of Thiocarbonates for Both the Production and the Biofunctionalization of Polymers
- (2009) Cyrille Boyer et al. MACROMOLECULAR RAPID COMMUNICATIONS
- Bottle-Brush Brushes: Cylindrical Molecular Brushes of Poly(2-oxazoline) on Glassy Carbon
- (2009) Ning Zhang et al. MACROMOLECULES
- Cylindrical Molecular Brushes of Poly(2-oxazoline)s from 2-Isopropenyl-2-oxazoline
- (2009) Ning Zhang et al. MACROMOLECULES
- Knocking down barriers: advances in siRNA delivery
- (2009) Kathryn A. Whitehead et al. NATURE REVIEWS DRUG DISCOVERY
- Subcellular targeting strategies for drug design and delivery
- (2009) Lawrence Rajendran et al. NATURE REVIEWS DRUG DISCOVERY
- Endocytosis and signalling: intertwining molecular networks
- (2009) Alexander Sorkin et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Diffusion Studies of Nanometer Polymersomes Across Tissue Engineered Human Oral Mucosa
- (2009) Vanessa Hearnden et al. PHARMACEUTICAL RESEARCH
- Targeting Angiogenesis-Dependent Calcified Neoplasms Using Combined Polymer Therapeutics
- (2009) Ehud Segal et al. PLoS One
- Atom transfer radical polymerization in inverse miniemulsion: A versatile route toward preparation and functionalization of microgels/nanogels for targeted drug delivery applications
- (2009) Jung Kwon Oh et al. POLYMER
- End group removal and modification of RAFT polymers
- (2009) Helen Willcock et al. Polymer Chemistry
- In situ growth of a stoichiometric PEG-like conjugate at a protein's N-terminus with significantly improved pharmacokinetics
- (2009) W. Gao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Bioactive surfaces and biomaterials via atom transfer radical polymerization
- (2009) F.J. Xu et al. PROGRESS IN POLYMER SCIENCE
- Synthesis of functional polymers with controlled architecture by CRP of monomers in the presence of cross-linkers: From stars to gels
- (2009) Haifeng Gao et al. PROGRESS IN POLYMER SCIENCE
- Immobilized ProteinâPolymer Nanoreactors
- (2009) Mariusz Grzelakowski et al. Small
- Advances in the synthesis of amphiphilic block copolymers via RAFT polymerization: Stimuli-responsive drug and gene delivery☆
- (2008) A YORK et al. ADVANCED DRUG DELIVERY REVIEWS
- Synthesis of Functional Polymers by Post-Polymerization Modification
- (2008) Marc A. Gauthier et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Different Internalization Pathways of Polymeric Micelles and Unimers and Their Effects on Vesicular Transport
- (2008) Gaurav Sahay et al. BIOCONJUGATE CHEMISTRY
- Poly(2-methacryloyloxyethyl phosphorylcholine) for Protein Conjugation
- (2008) Andrew Lewis et al. BIOCONJUGATE CHEMISTRY
- From Defined Reactive Diblock Copolymers to Functional HPMA-Based Self-Assembled Nanoaggregates
- (2008) M. Barz et al. BIOMACROMOLECULES
- Tumour-targeted nanomedicines: principles and practice
- (2008) T Lammers et al. BRITISH JOURNAL OF CANCER
- Phase III trial comparing paclitaxel poliglumex vs docetaxel in the second-line treatment of non-small-cell lung cancer
- (2008) L Paz-Ares et al. BRITISH JOURNAL OF CANCER
- RAFT polymerization: an avenue to functional polymeric micelles for drug delivery
- (2008) Martina Heide Stenzel CHEMICAL COMMUNICATIONS
- Synthesis and microwave assisted polymerization of fluorinated 2-phenyl-2-oxazolines: the fastest 2-oxazoline monomer to date
- (2008) Matthias Lobert et al. CHEMICAL COMMUNICATIONS
- Effect of end group polarity upon the lower critical solution temperature of poly(2-isopropyl-2-oxazoline)
- (2008) Stephan Huber et al. COLLOID AND POLYMER SCIENCE
- Non-cytotoxic polymer vesicles for rapid and efficient intracellular delivery
- (2008) Hannah Lomas et al. FARADAY DISCUSSIONS
- Synthetic polymeric substrates as potent pro-oxidant versus anti-oxidant regulators of cytoskeletal remodeling and cell apoptosis
- (2008) Hak-Joon Sung et al. JOURNAL OF CELLULAR PHYSIOLOGY
- The use of fluorescence microscopy to define polymer localisation to the late endocytic compartments in cells that are targets for drug delivery
- (2008) Simon C.W. Richardson et al. JOURNAL OF CONTROLLED RELEASE
- Pluronic block copolymers: Evolution of drug delivery concept from inert nanocarriers to biological response modifiers
- (2008) Elena V. Batrakova et al. JOURNAL OF CONTROLLED RELEASE
- Polymer brushes containing sulfonated sugar repeat units: Synthesis, characterization, andin vitrotesting of blood coagulation activation
- (2008) N. Ayres et al. JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY
- Synthesis of well-defined polymeric activated esters
- (2008) Patrick Theato JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY
- Polymerization of oligo(ethylene glycol) (meth)acrylates: Toward new generations of smart biocompatible materials
- (2008) Jean-François Lutz JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY
- Novel well-defined glycopolymers synthesized via the reversible addition fragmentation chain transfer process in aqueous media
- (2008) Zhicheng Deng et al. JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY
- N-Trimethylsilyl Amines for Controlled Ring-Opening Polymerization of Amino AcidN-Carboxyanhydrides and Facile End Group Functionalization of Polypeptides
- (2008) Hua Lu et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Poly-2-methyl-2-oxazoline: A Peptide-like Polymer for Protein-Repellent Surfaces
- (2008) Rupert Konradi et al. LANGMUIR
- Nanotube and Three-Way Nanotube Formation with Nonionic Amphiphilic Block Peptides
- (2008) Tatsuya Kanzaki et al. MACROMOLECULAR BIOSCIENCE
- Thermo-Responsive Polyoxazolines with Widely Tuneable LCST
- (2008) Christina Diehl et al. MACROMOLECULAR BIOSCIENCE
- Kinetic Investigations on the Polymerization of 2-Oxazolines Using Pluritriflate Initators
- (2008) Robert Luxenhofer et al. MACROMOLECULAR RAPID COMMUNICATIONS
- ‘Click’ Chemistry in Polymer and Material Science: An Update
- (2008) Wolfgang H. Binder et al. MACROMOLECULAR RAPID COMMUNICATIONS
- Poly(ethylene glycol)s generate complement activation products in human serum through increased alternative pathway turnover and a MASP-2-dependent process
- (2008) I. Hamad et al. MOLECULAR IMMUNOLOGY
- Factors Affecting the Clearance and Biodistribution of Polymeric Nanoparticles
- (2008) Frank Alexis et al. MOLECULAR PHARMACEUTICS
- Synthesis of novel ABA triblock and (ABA)n multiblock copolymers comprised of polyisobutylene and poly(γ-benzyl-l-glutamate) segments
- (2008) Tomoya Higashihara et al. REACTIVE & FUNCTIONAL POLYMERS
- Autoinflammatory diseases: an update of clinical and genetic aspects
- (2008) Q. Yao et al. RHEUMATOLOGY
- Near-Infrared Fluorescent Labeled Peptosome for Application to Cancer Imaging
- (2007) Hiroki Tanisaka et al. BIOCONJUGATE CHEMISTRY
- Accelerated blood clearance (ABC) phenomenon upon repeated injection of PEGylated liposomes
- (2007) Tatsuhiro Ishida et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Synthesis and characterization of poly(2-ethyl 2-oxazoline)-conjugates with proteins and drugs: Suitable alternatives to PEG-conjugates?
- (2007) Anna Mero et al. JOURNAL OF CONTROLLED RELEASE
- Acid-Degradable Core-Crosslinked Micelles Prepared from Thermosensitive Glycopolymers Synthesized via RAFT Polymerization
- (2007) Ling Zhang et al. MACROMOLECULAR RAPID COMMUNICATIONS
- Radical addition–fragmentation chemistry in polymer synthesis
- (2007) Graeme Moad et al. POLYMER
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started