Generation of a TP53-modified porcine cancer model by CRISPR/Cas9-mediated gene modification in porcine zygotes via electroporation

Efficient generation of P53 biallelic knockout Diannan miniature pigs via TALENs and somatic cell nuclear transfer

(2017) Youfeng Shen et al.   Journal of Translational Medicine

Gene targeting, genome editing: from Dolly to editors

(2016) Wenfang Tan et al.   TRANSGENIC RESEARCH

A porcine model of osteosarcoma

(2016) A Saalfrank et al.   Oncogenesis

Somatic cell reprogramming-free generation of genetically modified pigs

(2016) F. Tanihara et al.   Science Advances

A Genetic Porcine Model of Cancer

(2015) Lawrence B. Schook et al.   PLoS One

Astaxanthin present in the maturation medium reduces negative effects of heat shock on the developmental competence of porcine oocytes

(2015) Lanh Thi Kim Do et al.   Reproductive Biology

Use of the CRISPR/Cas9 System to Produce Genetically Engineered Pigs from In Vitro-Derived Oocytes and Embryos1

(2014) Kristin M. Whitworth et al.   BIOLOGY OF REPRODUCTION

Development and translational imaging of a TP53 porcine tumorigenesis model

(2014) Jessica C. Sieren et al.   JOURNAL OF CLINICAL INVESTIGATION

Easy quantitative assessment of genome editing by sequence trace decomposition

(2014) Eva K. Brinkman et al.   NUCLEIC ACIDS RESEARCH

Genetically modified pigs to model human diseases

(2013) Tatiana Flisikowska et al.   JOURNAL OF APPLIED GENETICS

Genetically Modified Pig Models for Human Diseases

(2013) Nana Fan et al.   Journal of Genetics and Genomics

Imaging and histological characterization of a human brain xenograft in pig: The first induced glioma model in a large animal

(2013) Laurent Selek et al.   JOURNAL OF NEUROSCIENCE METHODS

Efficient nonmeiotic allele introgression in livestock using custom endonucleases

(2013) W. Tan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNA-Guided Human Genome Engineering via Cas9

(2013) P. Mali et al.   SCIENCE

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

The new pig on the block: modelling cancer in pigs

(2013) Tatiana Flisikowska et al.   TRANSGENIC RESEARCH

A Porcine Model of Familial Adenomatous Polyposis

(2012) Tatiana Flisikowska et al.   GASTROENTEROLOGY

Genetically modified pigs for biomedical research

(2012) Yonglun Luo et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Inactivation and Inducible Oncogenic Mutation of p53 in Gene Targeted Pigs

(2012) Simon Leuchs et al.   PLoS One

Pig gene knockout by rAAV-mediated homologous recombination: comparison of BRCA1 gene knockout efficiency in Yucatan and Göttingen fibroblasts with slightly different target sequences

(2011) Yonglun Luo et al.   TRANSGENIC RESEARCH

High efficiency of BRCA1 knockout using rAAV-mediated gene targeting: developing a pig model for breast cancer

(2010) Yonglun Luo et al.   TRANSGENIC RESEARCH

Varying phenotypes in swine versus murine transgenic models constitutively expressing the same human Sonic hedgehog transcriptional activator, K5-HGLI2ΔN

(2010) Amy C. McCalla-Martin et al.   TRANSGENIC RESEARCH

COSMIC (the Catalogue of Somatic Mutations in Cancer): a resource to investigate acquired mutations in human cancer

(2009) Simon A. Forbes et al.   NUCLEIC ACIDS RESEARCH

Oncogenic Kras Initiates Leukemia in Hematopoietic Stem Cells

(2009) Amit J Sabnis et al.   PLOS BIOLOGY