Article
Health Care Sciences & Services
S. N. Mousavikia, M. T. Bahreyni Toossi, S. Khademi, M. Soukhtanloo, H. Azimian
Summary: This study evaluated DNA damage and antioxidant status in hospital workers occupationally exposed to low doses of ionizing radiation. The results showed that exposure to low doses of ionizing radiation leads to increased cytogenetic damage, but cannot cause an adaptive response or improve antioxidant capacity. Controlling healthcare workers' exposure is crucial for improving the health of hospital workers and the quality of patient care.
BMC HEALTH SERVICES RESEARCH
(2023)
Article
Nuclear Science & Technology
Tae Young Kong, Si Young Kim, Yoonhee Jung, Jeong Mi Kim, Moonhyung Cho
Summary: This paper provides a comprehensive overview of administrative dose control for occupationally-exposed workers in Korean nuclear power plants (NPPs), focusing on how dose limits and administrative dose constraints are implemented to resolve inequity of radiation exposure. The analysis results show how the implementation of administrative dose constraints impacted the occupational dose distributions in Korean NPPs during the years 2009-2018.
NUCLEAR ENGINEERING AND TECHNOLOGY
(2021)
Article
Biology
Iman M. Ahmad, Lisa Bartenhagen, Kimberly Michael, Maher Y. Abdalla
Summary: This study investigated the influence of occupational radiation exposure on oxidative stress and antioxidant levels among different hospital imaging professional groups. The results showed that imaging professionals exposed to radiation had higher levels of oxidative stress markers and antioxidant enzymes, compared to the control group. Furthermore, the results from the non-ionizing radiation group were significantly higher than the ionizing radiation group.
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
(2023)
Review
Biochemistry & Molecular Biology
Clemence Baudin, Marie-Odile Bernier, Dmitry Klokov, Maria Grazia Andreassi
Summary: This review focused on the genotoxicity biomarkers that are significantly elevated in health workers exposed to ionizing radiation compared to unexposed workers. The study found that chromosome aberrations (CA) and micronuclei (MN) frequencies were significantly different between the two groups, along with other endpoints like stable translocations, sister chromatid exchanges (SCE) and comet assay endpoints. Further studies are needed to validate the usefulness of these biomarkers in future epidemiological studies.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Multidisciplinary Sciences
Julie Lopes, Clemence Baudin, Juliette Feuardent, Herve Roy, Sylvaine Caer-Lorho, Klervi Leuraud, Marie-Odile Bernier
Summary: Medical personnel in France are occupationally exposed to ionizing radiation, but no study has been conducted to investigate the health risks associated with this exposure. The ORICAMs cohort is a nationwide French longitudinal study that aims to assess the risk of radiation-associated cancer and non-cancer mortality in medical workers. The cohort includes workers monitored for ionizing radiation exposure from 2002 to 2012. Initial analysis shows that the mortality rate among these workers is significantly lower than the national reference rates, but further research is needed to establish a potential relationship between occupational exposure and mortality risk.
Article
Environmental Sciences
Nihal Kilinc, Mehmet Onbasilar, Akin Cayir
Summary: This study investigated the plasma concentration of cell-free nucleic acids in radiology workers and found that the concentration of ccfRNA was significantly correlated with working time and imaging number, while total working time was significantly associated with total ccfRNA concentration. These findings suggest that total RNA can be used to predict radiation exposure risk and that working time and imaging parameters can alter the level of free nucleic acids.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Nuclear Science & Technology
A. Pitzschke
Summary: The average daily natural background dose was calculated using a statistical approach from personal dosemeter records of professionally exposed workers in Switzerland, with values varying depending on geographic location. Measurements with control dosemeters at customer sites were consistent with computed values, but geographic variation and inaccurate correction may result in dose record discrepancies. Up to 3% of dose records during quarterly surveillance periods are expected to be false positives or negatives.
RADIATION MEASUREMENTS
(2021)
Article
Multidisciplinary Sciences
Tamara V. Azizova, Evgeniya S. Grigoryeva, Nobuyuki Hamada
Summary: Research shows that there is a correlation between radiation dose rate and the risk of mortality from ischemic heart disease among occupationally chronically exposed workers. The risk increases with higher dose rates, and also with longer duration of exposure at high rates. These findings contribute to the scientific basis for recommendations on the radiation protection system.
SCIENTIFIC REPORTS
(2023)
Article
Neurosciences
Gehad Ahmed Abo-El-Ata, Fatma Hossni Abdellatif Abdelghany, Marwa Farghaly Ahmed, Marwa Abdelgwad, Mona Abdallah Ramadan
Summary: This study investigated the impact of occupational exposure to air pollutants on the neuropsychiatric health. The results showed that the exposed workers demonstrated impaired neuropsychological functions and increased serum levels of 4HNE compared to the control group. This suggests that occupational exposure to air pollutants can have detrimental effects on the neuropsychiatric health of pottery workers.
Article
Environmental Sciences
Mona Mohamed Taha, Nagat Mohamed Amer, Safia Beshir, Heba Mahdy-Abdallah
Summary: The study investigated the relationship between hearing loss and blood pressure variation in textile workers, finding an association between HSP70 genotypes and hypertension, with smoking also influencing the results.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
Taru Goyal, Prasenjit Mitra, Preeti Singh, Raghumoy Ghosh, Malavika Lingeswaran, Shailja Sharma, Praveen Sharma
Summary: Occupational exposure to lead has a significant impact on workers' immune system and parameters, leading to immune cell dysfunction and increased pro-inflammatory response.
BIOLOGICAL TRACE ELEMENT RESEARCH
(2021)
Article
Public, Environmental & Occupational Health
Yeqing Gu, Jinhan Wang, Yan Wang, Chang Xu, Yang Liu, Liqing Du, Qin Wang, Kaihua Ji, Ningning He, Manman Zhang, Huijuan Song, Kaijun Niu, Qiang Liu
Summary: This study aimed to estimate the quantified relationships between low-dose radiation exposures and site-specific solid cancers among Chinese medical X-ray workers. The results showed a positive relationship between cumulative organ-specific dose and liver, esophagus, thyroid, and non-melanoma skin cancers, as well as a significant risk increase for liver, stomach, breast cancer (female), thyroid, and non-melanoma skin cancers.
OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
(2023)
Article
Environmental Sciences
Bruna Gauer, Elisa Sauer, Sabrina Nascimento, Gabriela Goethel, Caroline Peruzzi, Ingrid Flesch, Nuryan Fao, Larissa Cestonaro, Tatiana Sant'Pierre, Adriana Gioda, Ursula Matte, Natalia Brucker, Solange Cristina Garcia
Summary: This study evaluated the potential effects of chronic exposure to chemical agents from air pollution on the expressions of peripheral biomarkers and tumor-related proteins. Results showed increased levels of urinary 1-hydroxypyrene and blood As and Ni in taxi drivers, associated with inflammatory and oxidative stress biomarkers, suggesting a common source of exposure. Furthermore, gene expression of p53, CD26 and ICAM-1 were decreased in taxi drivers, indicating a commom regulation point. Antioxidants were negatively associated with inflammatory biomarkers, maybe regulating the immune-response.
Article
Toxicology
Changmao Long, Guiping Hu, Pai Zheng, Tian Chen, Zekang Su, Yali Zhang, Chunguang Ding, Fangda Peng, Shanfa Yu, Tiancheng Wang, Guang Jia
Summary: This study utilized UPLC-MS non-targeted metabolomics to analyze serum metabolic changes in chromate exposure workers and controls, revealing decreases in 13 metabolites and increases in 41 metabolites related to arginine, proline, and glycerophospholipid metabolism. Additionally, significant negative correlations were found between blood Cr level and certain metabolites, primarily among male subgroups. The potential influence of diet as a confounding factor was highlighted, requiring further verification in future research.
TOXICOLOGY LETTERS
(2021)
Article
Public, Environmental & Occupational Health
Yana Bai, Jingli Yang, Zhiyuan Cheng, Desheng Zhang, Ruonan Wang, Rui Zhang, Zhao Bai, Shan Zheng, Minzhen Wang, Chun Yin, Xiaobin Hu, Yufeng Wang, Lulu Xu, Yarong Chen, Jing Li, Siyu Li, Yujia Hu, Na Li, Wenling Zhang, Yanyan Liu, Juansheng Li, Xiaowei Ren, Feng Kang, Xijiang Wu, Jiao Ding, Ning Cheng
Summary: The Jinchang Cohort is a long-term cohort study on a unique occupational population with metal exposures, aiming to explore the pathogenesis of multi-etiology and multi-disease and evaluate the effects of intervention measures.
EUROPEAN JOURNAL OF EPIDEMIOLOGY
(2022)
Review
Biology
Mark P. Little, Tamara Azizova, Nobuyuki Hamada
Summary: Studies have shown correlations between ionizing radiation and circulatory diseases, cataracts, and other ocular endpoints, with dose-response relationships observed. Additionally, neurological detriment may occur following radiation exposure at low-moderate doses.
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
(2021)
Article
Biology
Tamara V. Azizova, Maria V. Bannikova, Evgeniya S. Grigoryeva, Valentina L. Rybkina
Summary: The study found that occupational exposure to low dose-rate ionizing radiation at the Russian nuclear facility Mayak Production Association (PA) increases the risk of basal cell carcinoma (BCC), but does not significantly affect the risk of squamous cell carcinoma (SCC). Gender, age at hire, attained age, and facility type did not have a significant impact on the incidence risk of BCC and SCC.
RADIATION AND ENVIRONMENTAL BIOPHYSICS
(2021)
Article
Environmental Sciences
Tamara Azizova, Maria Bannikova, Evgeniya S. Grigoryeva, Ksenia Briks, Nobuyuki Hamada
Summary: This study investigated mortality from diseases of the circulatory system (DCS) in Russian nuclear workers and found no significant associations between mortality and gamma-ray exposure or internal exposure to plutonium. However, a significant association was observed between gamma-ray exposure and mortality from ischemic stroke in male workers in the subcohort. Positive associations were also found between internal exposure and mortality from DCS and ischemic heart disease (IHD) in women.
JOURNAL OF RADIOLOGICAL PROTECTION
(2022)
Article
Biology
Tamara Azizova, Maria B. Moseeva, Evgeniya S. Grigoryeva, Nobuyuki Hamada
Summary: This study reports the incidence risks for cerebrovascular diseases and strokes in a cohort of Russian nuclear workers chronically exposed to ionizing radiation. The findings suggest a significant association between cumulative radiation dose and CeVD incidence, but no significant association with stroke or its types.
RADIATION AND ENVIRONMENTAL BIOPHYSICS
(2022)
Editorial Material
Biology
Elizabeth A. Ainsbury, Claudia Dalke, Mariateresa Mancuso, Munira Kadhim, Roy A. Quinlan, Tamara Azizova, Lawrence T. Dauer, Joseph R. Dynlacht, Rick Tanner, Nobuyuki Hamada
Summary: Recent studies have shown that the lens of the eye is more sensitive to radiation than previously believed, leading to a reduction in occupational lens dose limits in the European Union countries, Japan, and elsewhere. This Commentary introduces the work of the LDLensRad Consortium in advancing the understanding of the mechanisms of low dose radiation cataract.
RADIATION RESEARCH
(2022)
Article
Oncology
Tamara V. Azizova, Evgeny V. Bragin, Maria V. Bannikova, Nobuyuki Hamada, Evgeniya S. Grigoryeva
Summary: This study reports an increased risk of normal-tension glaucoma (NTG) in radiation workers exposed to chronic doses greater than 1Gy. If confirmed in other cohorts, this finding has significant implications for normal tissue complications in radiotherapy patients and ocular radiation protection in radiation workers.
Article
Biology
Tamara Azizova, Maria Bannikova, Ksenia Briks, Evgeniya S. Grigoryeva, Nobuyuki Hamada
Summary: Heart diseases are a major cause of death. A study on a cohort of Russian nuclear workers revealed that chronic occupational exposure to external gamma and/or internal alpha radiation is associated with an increased risk of certain types of heart diseases. Linear model analysis showed a positive correlation between the risks and gamma radiation dose, which remained significant after adjusting for non-radiation factors.
RADIATION AND ENVIRONMENTAL BIOPHYSICS
(2023)
Article
Hematology
T. Azizova, E. Bragin, M. Bannikova, E. S. Grigoryeva, A. Korobkin
Summary: This study aimed to assess the incidence and mortality rates of malignant neoplasms of the hematopoietic and lymphoid tissues (HLTT) in workers chronically exposed to occupational ionizing radiation. The results showed that the rates were associated with sex, attained age, and follow-up period, with higher rates in males compared to females. The study also revealed an increasing trend in the incidence rates of chronic leukemia and lymphoma by the end of the follow-up period.
GEMATOLOGIYA I TRANSFUZIOLOGIYA
(2023)
Article
Environmental Sciences
Sergey Osovets, Tamara Azizova, Maria B. Moseeva
Summary: This study aimed to estimate threshold doses and uncertainties for human health effects after short-term high-dose-rate radiation exposure. Results showed that the effective dose threshold technique provided more accurate and statistically significant threshold dose estimates compared to the quantile technique, which had higher relative uncertainties.
RADIATION PROTECTION DOSIMETRY
(2023)
