Daily zeaxanthin supplementation prevents atrophy of the retinal pigment epithelium (RPE) in a mouse model of mitochondrial oxidative stress

Retinal accumulation of zeaxanthin, lutein, and β-carotene in mice deficient in carotenoid cleavage enzymes

(2017) Binxing Li et al.   EXPERIMENTAL EYE RESEARCH

The impact of oxidative stress and inflammation on RPE degeneration in non-neovascular AMD

(2017) Sayantan Datta et al.   PROGRESS IN RETINAL AND EYE RESEARCH

4-Hydroxy-7-oxo-5-heptenoic Acid Lactone Induces Angiogenesis through Several Different Molecular Pathways

(2016) Junhong Guo et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Mesozeaxanthin Protects Retina from Oxidative Stress in a Rat Model

(2016) Cemal Orhan et al.   JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS

Optical Coherence Tomography Reflective Drusen Substructures Predict Progression to Geographic Atrophy in Age-related Macular Degeneration

(2016) Malini Veerappan et al.   OPHTHALMOLOGY

Expression of Human Complement Factor H Prevents Age-Related Macular Degeneration–Like Retina Damage and Kidney Abnormalities in Aged Cfh Knockout Mice

(2015) Jin-Dong Ding et al.   AMERICAN JOURNAL OF PATHOLOGY

Systemic treatment with a 5HT1a agonist induces anti-oxidant protection and preserves the retina from mitochondrial oxidative stress

(2015) Manas R. Biswal et al.   EXPERIMENTAL EYE RESEARCH

A mitochondrial superoxide theory for oxidative stress diseases and aging

(2015) Hiroko P. Indo et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Zeaxanthin Inhibits Hypoxia-Induced VEGF Secretion by RPE Cells through Decreased Protein Levels of Hypoxia-Inducible Factors-1α

(2015) Richard Rosen et al.   Biomed Research International

Inactivity of human  , -carotene-9',10'-dioxygenase (BCO2) underlies retinal accumulation of the human macular carotenoid pigment

(2014) B. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Zeaxanthin induces Nrf2-mediated phase II enzymes in protection of cell death

(2014) X Zou et al.   Cell Death & Disease

Secondary Analyses of the Effects of Lutein/Zeaxanthin on Age-Related Macular Degeneration Progression

(2014) Emily Y. Chew et al.   JAMA Ophthalmology

Regulation of MnSOD Enzymatic Activity by Sirt3 Connects the Mitochondrial Acetylome Signaling Networks to Aging and Carcinogenesis

(2013) Randa Tao et al.   ANTIOXIDANTS & REDOX SIGNALING

Long-Term Effects of Vitamins C and E, β-Carotene, and Zinc on Age-related Macular Degeneration

(2013) Emily Y. Chew et al.   OPHTHALMOLOGY

Lutein and zeaxanthin supplementation reduces photooxidative damage and modulates the expression of inflammation-related genes in retinal pigment epithelial cells

(2012) Qingning Bian et al.   FREE RADICAL BIOLOGY AND MEDICINE

Consequences of oxidative stress in age-related macular degeneration

(2012) Stuart G. Jarrett et al.   MOLECULAR ASPECTS OF MEDICINE

Enhanced glutathione depletion, protein adduct formation, and cytotoxicity following exposure to 4-hydroxy-2-nonenal (HNE) in cells expressing human multidrug resistance protein-1 (MRP1) together with human glutathione S-transferase-M1 (GSTM1)

(2011) Lisa P. Rudd et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Complement factor H binds malondialdehyde epitopes and protects from oxidative stress

(2011) David Weismann et al.   NATURE

A Rat Model for Choroidal Neovascularization Using Subretinal Lipid Hydroperoxide Injection

(2010) Takayuki Baba et al.   AMERICAN JOURNAL OF PATHOLOGY

Age-related accumulation of 3-nitrotyrosine and nitro-A2E in human Bruch's membrane

(2010) L.S. Murdaugh et al.   EXPERIMENTAL EYE RESEARCH

The Relationship of Dietary ω-3 Long-Chain Polyunsaturated Fatty Acid Intake With Incident Age-Related Macular Degeneration

(2008) John Paul SanGiovanni   ARCHIVES OF OPHTHALMOLOGY

Dose translation from animal to human studies revisited

(2007) Shannon Reagan-Shaw et al.   FASEB JOURNAL