Heterogeneity of circulating CD8 T-cells specific to islet, neo-antigen and virus in patients with type 1 diabetes mellitus

Approximated and User Steerable tSNE for Progressive Visual Analytics

(2017) Nicola Pezzotti et al.   IEEE TRANSACTIONS ON VISUALIZATION AND COMPUTER GRAPHICS

Autoimmunity against a defective ribosomal insulin gene product in type 1 diabetes

(2017) Maria J L Kracht et al.   NATURE MEDICINE

Type 1 diabetes induction in humanized mice

(2017) Shulian Tan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Visual analysis of mass cytometry data by hierarchical stochastic neighbour embedding reveals rare cell types

(2017) Vincent van Unen et al.   Nature Communications

Cytosplore: Interactive Immune Cell Phenotyping for Large Single-Cell Datasets

(2016) T. Höllt et al.   COMPUTER GRAPHICS FORUM

Hierarchical Stochastic Neighbor Embedding

(2016) N. Pezzotti et al.   COMPUTER GRAPHICS FORUM

Tissue-resident memory T cells

(2013) Haina Shin et al.   IMMUNOLOGICAL REVIEWS

Coexpression of CD49b and LAG-3 identifies human and mouse T regulatory type 1 cells

(2013) Nicola Gagliani et al.   NATURE MEDICINE

CD8 T cell autoreactivity to preproinsulin epitopes with very low human leucocyte antigen class I binding affinity

(2012) J. R. F. Abreu et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients

(2012) Ken T. Coppieters et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Self-reactive human CD4 T cell clones form unusual immunological synapses

(2012) David A. Schubert et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Discovery of low-affinity preproinsulin epitopes and detection of autoreactive CD8 T-cells using combinatorial MHC multimers

(2011) Wendy W. Unger et al.   JOURNAL OF AUTOIMMUNITY

Simultaneous Detection of Circulating Autoreactive CD8+ T-Cells Specific for Different Islet Cell-Associated Epitopes Using Combinatorial MHC Multimers

(2010) J. H. Velthuis et al.   DIABETES

Analysis of CD161 expression on human CD8+ T cells defines a distinct functional subset with tissue-homing properties

(2010) E. Billerbeck et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA