The anticancer peptide RT53 induces immunogenic cell death

Oncolytic peptide LTX-315 induces an immune-mediated abscopal effect in a rat sarcoma model

(2017) Janne Nestvold et al.   OncoImmunology

A Cell-Penetrating Peptide Targeting AAC-11 Specifically Induces Cancer Cells Death

(2016) Léonard Jagot-Lacoussiere et al.   CANCER RESEARCH

The oncolytic peptide LTX-315 overcomes resistance of cancers to immunotherapy with CTLA4 checkpoint blockade

(2016) T Yamazaki et al.   CELL DEATH AND DIFFERENTIATION

Discovery of a 9-mer Cationic Peptide (LTX-315) as a Potential First in Class Oncolytic Peptide

(2016) Bengt Erik Haug et al.   JOURNAL OF MEDICINAL CHEMISTRY

The oncolytic peptide LTX-315 triggers immunogenic cell death

(2016) H Zhou et al.   Cell Death & Disease

Vaccination with Necroptotic Cancer Cells Induces Efficient Anti-tumor Immunity

(2016) Tania Løve Aaes et al.   Cell Reports

The oncolytic peptide LTX-315 triggers necrotic cell death

(2015) Sabrina Forveille et al.   CELL CYCLE

DNA damage-induced nuclear translocation of Apaf-1 is mediated by nucleoporin Nup107

(2015) Léonard Jagot-Lacoussiere et al.   CELL CYCLE

Live to die another way: modes of programmed cell death and the signals emanating from dying cells

(2015) Yaron Fuchs et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

RIPK1 and NF- B signaling in dying cells determines cross-priming of CD8+ T cells

(2015) N. Yatim et al.   SCIENCE

The oncolytic peptide LTX-315 kills cancer cells through Bax/Bak-regulated mitochondrial membrane permeabilization

(2015) Heng Zhou et al.   Oncotarget

Complete regression and systemic protective immune responses obtained in B16 melanomas after treatment with LTX-315

(2014) Ketil André Camilio et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

High hydrostatic pressure induces immunogenic cell death in human tumor cells

(2014) Jitka Fucikova et al.   INTERNATIONAL JOURNAL OF CANCER

Newcastle disease virotherapy induces long-term survival and tumor-specific immune memory in orthotopic glioma through the induction of immunogenic cell death

(2014) Carolien A. Koks et al.   INTERNATIONAL JOURNAL OF CANCER

Screening of novel immunogenic cell death inducers within the NCI Mechanistic Diversity Set

(2014) Abdul Qader Sukkurwala et al.   OncoImmunology

LTX-315 (Oncopore™)

(2014) Ketil André Camilio et al.   OncoImmunology

Consensus guidelines for the detection of immunogenic cell death

(2014) Oliver Kepp et al.   OncoImmunology

Trial Watch

(2014) Erika Vacchelli et al.   OncoImmunology

Defective immunogenic cell death of HMGB1-deficient tumors: compensatory therapy with TLR4 agonists

(2013) T Yamazaki et al.   CELL DEATH AND DIFFERENTIATION

Protective Role of the Inflammatory CCR2/CCL2 Chemokine Pathway through Recruitment of Type 1 Cytotoxic    T Lymphocytes to Tumor Beds

(2013) T. Lanca et al.   JOURNAL OF IMMUNOLOGY

Immunogenic Cell Death in Cancer Therapy

(2012) Guido Kroemer et al.   Annual Review of Immunology

PD-1 Blockade Enhances T-cell Migration to Tumors by Elevating IFN-  Inducible Chemokines

(2012) W. Peng et al.   CANCER RESEARCH

Recent Advances in Computational Modeling of α.-Helical Membrane- Active Peptides

(2012) Anton Polyansky et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Cardiac Glycosides Exert Anticancer Effects by Inducing Immunogenic Cell Death

(2012) L. Menger et al.   Science Translational Medicine

Hypericin-based photodynamic therapy induces surface exposure of damage-associated molecular patterns like HSP70 and calreticulin

(2011) Abhishek D. Garg et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Chemotherapy Induces Intratumoral Expression of Chemokines in Cutaneous Melanoma, Favoring T-cell Infiltration and Tumor Control

(2011) M. Hong et al.   CANCER RESEARCH

Maximal T Cell-Mediated Antitumor Responses Rely upon CCR5 Expression in Both CD4+ and CD8+ T Cells

(2011) A. Gonzalez-Martin et al.   CANCER RESEARCH

Autophagy-Dependent Anticancer Immune Responses Induced by Chemotherapeutic Agents in Mice

(2011) M. Michaud et al.   SCIENCE

Desirable cell death during anticancer chemotherapy

(2010) Clara Locher et al.   Annals of the New York Academy of Sciences

Antitumor Effect after Radiofrequency Ablation of Murine Hepatoma Is Augmented by an Active Variant of CC Chemokine Ligand 3/Macrophage Inflammatory Protein-1 

(2010) N. Iida et al.   CANCER RESEARCH

Immunogenic Tumor Cell Death for Optimal Anticancer Therapy: The Calreticulin Exposure Pathway

(2010) L. Zitvogel et al.   CLINICAL CANCER RESEARCH

Restoration of the immunogenicity of cisplatin-induced cancer cell death by endoplasmic reticulum stress

(2010) I Martins et al.   ONCOGENE

Anticancer peptide PNC-27 adopts an HDM-2-binding conformation and kills cancer cells by binding to HDM-2 in their membranes

(2010) E. Sarafraz-Yazdi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chemokine Expression in Melanoma Metastases Associated with CD8+ T-Cell Recruitment

(2009) H. Harlin et al.   CANCER RESEARCH

The antiapoptotic protein AAC-11 interacts with and regulates Acinus-mediated DNA fragmentation

(2009) Patricia Rigou et al.   EMBO JOURNAL

Mechanisms of pre-apoptotic calreticulin exposure in immunogenic cell death

(2009) Theocharis Panaretakis et al.   EMBO JOURNAL

Targeting AAC-11 in cancer therapy

(2009) Audrey Faye et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Optimization of Dendritic Cell Loading With Tumor Cell Lysates for Cancer Immunotherapy

(2009) Paul Hatfield et al.   JOURNAL OF IMMUNOTHERAPY

Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β–dependent adaptive immunity against tumors

(2009) François Ghiringhelli et al.   NATURE MEDICINE