Overexpression of the VRK1 kinase, which is associated with breast cancer, induces a mesenchymal to epithelial transition in mammary epithelial cells

VRK1 phosphorylates and protects NBS1 from ubiquitination and proteasomal degradation in response to DNA damage

(2016) Diana M. Monsalve et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

High VRK1 expression contributes to cell proliferation and survival in hepatocellular carcinoma

(2016) Wei Huang et al.   PATHOLOGY RESEARCH AND PRACTICE

E-cadherin re-expression shows in vivo evidence for mesenchymal to epithelial transition in clonal metastatic breast tumor cells

(2016) Katie Palen et al.   Oncotarget

VRK1 chromatin kinase phosphorylates H2AX and is required for foci formation induced by DNA damage

(2015) Marcella Salzano et al.   Epigenetics

The relevance of EMT in breast cancer metastasis: Correlation or causality?

(2015) Ruben Bill et al.   FEBS LETTERS

Vaccinia-related kinase 1 (VRK1) confers resistance to DNA-damaging agents in human breast cancer by affecting DNA damage response

(2015) Marcella Salzano et al.   Oncotarget

Interactions between Twist and other core epithelial–mesenchymal transition factors are controlled by GSK3-mediated phosphorylation

(2013) Rachel Lander et al.   Nature Communications

Rewiring of human lung cell lineage and mitotic networks in lung adenocarcinomas

(2013) Il-Jin Kim et al.   Nature Communications

Molecular genetic analysis of VRK1 in mammary epithelial cells: depletion slows proliferation in vitro and tumor growth and metastasis in vivo

(2013) T P Molitor et al.   Oncogenesis

Spatiotemporal Regulation of Epithelial-Mesenchymal Transition Is Essential for Squamous Cell Carcinoma Metastasis

(2012) Jeff H. Tsai et al.   CANCER CELL

Vaccinia-related Kinase 1 (VRK1) Is an Upstream Nucleosomal Kinase Required for the Assembly of 53BP1 Foci in Response to Ionizing Radiation-induced DNA Damage

(2012) Marta Sanz-García et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Epithelial-mesenchymal transition can suppress major attributes of human epithelial tumor-initiating cells

(2012) Toni Celià-Terrassa et al.   JOURNAL OF CLINICAL INVESTIGATION

The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups

(2012) Christina Curtis et al.   NATURE

Canonical Wnt signaling regulates Slug activity and links epithelial-mesenchymal transition with epigenetic Breast Cancer 1, Early Onset (BRCA1) repression

(2012) Z.-Q. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The kinase VRK1 is required for normal meiotic progression in mammalian oogenesis

(2011) Carolyn S. Schober et al.   MECHANISMS OF DEVELOPMENT

The Human Herpesvirus-7 (HHV-7) U21 Immunoevasin Subverts NK-Mediated Cytoxicity through Modulation of MICA and MICB

(2011) Christine L. Schneider et al.   PLoS Pathogens

Breast carcinoma cells re-express E-cadherin during mesenchymal to epithelial reverting transition

(2010) Yvonne L Chao et al.   Molecular Cancer

Cell adhesion: integrating cytoskeletal dynamics and cellular tension

(2010) J. Thomas Parsons et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Vaccinia-Related Kinase 1 Is Required for the Maintenance of Undifferentiated Spermatogonia in Mouse Male Germ Cells

(2010) Yoon Ha Choi et al.   PLoS One

Cell spreading as a hydrodynamic process

(2010) M. A. Fardin et al.   Soft Matter

Mice Deficient in the Serine/Threonine Protein Kinase VRK1 Are Infertile Due to a Progressive Loss of Spermatogonia1

(2009) Matthew S. Wiebe et al.   BIOLOGY OF REPRODUCTION

miR-200 Enhances Mouse Breast Cancer Cell Colonization to Form Distant Metastases

(2009) Derek M. Dykxhoorn et al.   PLoS One

Sixteen-Kinase Gene Expression Identifies Luminal Breast Cancers with Poor Prognosis

(2008) P. Finetti et al.   CANCER RESEARCH

VRK1 phosphorylates CREB and mediates CCND1 expression

(2008) T.-H. Kang et al.   JOURNAL OF CELL SCIENCE

SmgGDS is up-regulated in prostate carcinoma and promotes tumour phenotypes in prostate cancer cells

(2008) H Zhi et al.   JOURNAL OF PATHOLOGY

Human VRK1 Is an Early Response Gene and Its Loss Causes a Block in Cell Cycle Progression

(2008) Alberto Valbuena et al.   PLoS One

Prognostic Breast Cancer Signature Identified from 3D Culture Model Accurately Predicts Clinical Outcome across Independent Datasets

(2008) Katherine J. Martin et al.   PLoS One