Article
Medicine, General & Internal
Bartosz Karolak, Michal Ciurzynski, Marta Skowronska, Katarzyna Kurnicka, Magdalena Plywaczewska, Aleksandra Furdyna, Katarzyna Perzanowska-Brzeszkiewicz, Barbara Lichodziejewska, Szymon Pacho, Michal Machowski, Piotr Bienias, Malgorzata Wisniewska, Marek Golebiowski, Piotr Pruszczyk
Summary: In the NOAC era, most low-risk acute pulmonary embolism (APE) patients can be treated at home, but identifying those at very low risk of clinical deterioration may be challenging. This study aimed to propose a risk stratification algorithm for sPESI 0 point APE patients, allowing them to select candidates for safe outpatient treatment.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Yizhuo Gao, Yu Wang, Xia Cao, Xiaoxu Wang, Qiang Zheng, Hang Zhao, Dong Jia
Summary: By combining multiple CT parameters, a simple tool was developed for individualized risk assessment of deterioration in non-high-risk acute PE patients at admission. The right-to-left ventricular diameter ratio in the 4-chamber view and pulmonary vein filling abnormality were found to be related to deterioration risk. The developed nomogram had AUROC values of 0.91 in the derivation cohort and 0.89 in the validation cohort.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Paul D. Stein, Fadi Matta, Mary J. Hughes
Summary: The study found that low-risk patients with PE did not have lower mortality with catheter-directed thrombolysis or intravenous thrombolytic therapy than with anticoagulants alone.
AMERICAN JOURNAL OF CARDIOLOGY
(2021)
Article
Hematology
Carmen Rodriguez, Alfonso Muriel, Luis Carrasco, Sara Gonzalez, Winnifer Briceno, Diego Duran, Ana Retegui, Roger D. Yusen, Behnood Bikdeli, David Jimenez
Summary: Consensus statements suggest using the National Early Warning Score 2 (NEWS2) to identify stable patients with acute pulmonary embolism (PE) at intermediate-high risk. This study aimed to validate NEWS2 externally and compare it to the Bova score. The results showed that Bova outperformed NEWS2 in predicting a complicated course among stable PE patients, although addition of troponin testing and echocardiography improved the specificity of NEWS2.
SEMINARS IN THROMBOSIS AND HEMOSTASIS
(2023)
Review
Medicine, General & Internal
Antonio Leidi, Stijn Bex, Marc Righini, Amandine Berner, Olivier Grosgurin, Christophe Marti
Summary: Risk stratification plays a crucial role in the management of acute pulmonary embolism, helping to determine the appropriate diagnostic and therapeutic strategies. Patients are categorized into low-risk, intermediate-risk, and intermediate-high-risk groups based on clinical parameters and markers of right ventricular dysfunction and myocardial injury. This classification guides the choice of treatment and helps identify patients who may benefit from more aggressive approaches.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Emergency Medicine
Joseph R. Bledsoe, Scott C. Woller, Scott M. Stevens, Valerie Aston, Rich Patten, Todd Allen, Benjamin D. Horne, Lydia Dong, James Lloyd, Greg Snow, Troy Madsen, Patrick Fink, C. Gregory Elliott
Summary: This study evaluated the cost-effectiveness and length-of-stay difference between early discharge and observation management for low-risk pulmonary embolism patients in the emergency department. The results showed that patients managed with emergency department observation had a shorter length of stay and lower total encounter costs compared to those managed with hospital observation.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2021)
Article
Surgery
Danielle C. Sutzko, Andrea T. Obi, Neil Kamdar, Monita Karamkar, Thomas W. Wakefield, Nicholas H. Osborne, Peter K. Henke
Summary: This retrospective cohort study examined the incidence, morbidity, and mortality of VTE in postoperative patients within a quality collaborative, revealing that despite widespread use of postoperative thromboprophylaxis, no decrease in VTE incidence was observed.
Article
Hematology
Yuta Tsujisaka, Yugo Yamashita, Takeshi Morimoto, Toru Takase, Seiichi Hiramori, Kitae Kim, Maki Oi, Masaharu Akao, Yohei Kobayashi, Po-Min Chen, Koichiro Murata, Yoshiaki Tsuyuki, Yuji Nishimoto, Jiro Sakamoto, Kiyonori Togi, Hiroshi Mabuchi, Kensuke Takabayashi, Takao Kato, Koh Ono, Takeshi Kimura
Summary: The RIETE score can be used to identify low-risk pulmonary embolism patients for home treatment, and it shows better predictive ability than the sPESI score.
THROMBOSIS RESEARCH
(2023)
Review
Infectious Diseases
Li-yan Cui, Wen-wen Cheng, Zhi-wei Mou, Duan Xiao, Yun-yi Li, Yu-jie Li, Wan-ting Li, Zhuo-ming Chen
Summary: The risk factors for pulmonary embolism in COVID-19 patients are different from classic risk factors and may vary in diverse study populations.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2021)
Article
Cardiac & Cardiovascular Systems
Cecilia Becattini, Giorgio Maraziti, David R. Vinson, Austin C. C. Ng, Paul L. den Exter, Benoit Cote, Simone Vanni, Rami Doukky, Danai Khemasuwan, Anthony J. Weekes, Thiago Horta Soares, Savas Ozsu, Hernan Polo Friz, Serhat Erol, Giancarlo Agnelli, David Jimenez
Summary: Assessing right ventricle dysfunction (RVD) or elevated troponin levels can improve identification of low-risk patients with acute pulmonary embolism (PE), who may benefit from outpatient management or short hospital stay.
EUROPEAN HEART JOURNAL
(2021)
Article
Medicine, General & Internal
Monika Lisicka, Marta Skowronska, Bartosz Karolak, Jan Wojcik, Piotr Pruszczyk, Piotr Bienias
Summary: The association between heart rate variability and mortality risk of acute pulmonary embolism, as well as its association with right ventricular overload, is significant. HRV parameters were found to be significantly correlated with echocardiographic and biochemical signs of RV overload. These findings suggest that HRV parameters are influenced by RV overload and are associated with risk stratification in acute pulmonary embolism.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Jitka Starekova, Scott K. Nagle, Mark L. Schiebler, Scott B. Reeder, Venkata N. Meduri
Summary: This retrospective observational study described the clinical experience with Ferumoxytol-enhanced magnetic resonance angiography (Fe-MRA) in pregnant women with suspected pulmonary embolism (PE). The study found that Fe-MRA is a radiation- and gadolinium-free alternative for diagnosing PE during pregnancy.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2023)
Article
Medical Laboratory Technology
Bugra Kerget, Hatice Beyza Ozkan, Dursun Erol Afsin, Abdullah Osman Kocak, Esra Laloglu, Elif Yilmazel Ucar, Leyla Saglam
Summary: This study evaluated the relationship between YKL-40 level and clinical risk score in patients with pulmonary embolism (PE). The results showed that pulmonary artery obstruction index (PAOI) correlated with PE risk, and YKL-40 level was higher in the high-risk PE group compared to the high-intermediate-risk group. In high-risk PE patients, YKL-40 may be an important biomarker in decisions regarding early thrombolytic treatment.
CLINICAL BIOCHEMISTRY
(2022)
Article
Hematology
Slobodan Obradovic, Bojana Subotic, Boris Dzudovic, Jovan Matijasevic, Jelena Dzudovic, Sonja Salinger-Martinovic, Vladimir Miloradovic, Tamara Kovacevic-Preradovic, Jelena Marinkovic, Aleksandar Neskovic
Summary: In this study, a novel PEBSI score was developed to assess the risk of major bleeding in acute pulmonary embolism patients receiving thrombolytic therapy. The score showed significant power in discriminating patients with low risk for major bleeding from those with high risk.
THROMBOSIS RESEARCH
(2022)
Article
Hematology
Ibrahim Adda-Rezig, Johann Cossu, Nicolas Falvo, Fiona Ecarnot, Thibaut Desmettre, Nicolas Meneveau, Gregory Piazza, Romain Chopard
Summary: This study compared the effectiveness and safety of home treatment and recommended early discharge management in patients with pulmonary embolism (PE) at 3 months. The results showed that home treatment was as effective and safe as early discharge management in terms of primary outcomes.
THROMBOSIS RESEARCH
(2023)
Review
Health Care Sciences & Services
Jean-Baptiste Briere, Kevin Bowrin, Craig Coleman, Laurent Fauchier, Pierre Levy, Kerstin Folkerts, Mondher Toumi, Vanessa Taieb, Aurelie Millier, Olivia Wu
EXPERT REVIEW OF PHARMACOECONOMICS & OUTCOMES RESEARCH
(2019)
Article
Pharmacology & Pharmacy
Brandon K. Martinez, William L. Baker, Nitesh A. Sood, Thomas J. Bunz, Anna-Katharina Meinecke, Daniel Eriksson, Craig Coleman
Article
Cardiac & Cardiovascular Systems
Brandon K. Martinez, William L. Baker, Anna Konopka, Devon Giannelli, Craig I. Coleman, Jeffrey Kluger, Edmond M. Cronin
Review
Endocrinology & Metabolism
C. I. Coleman, E. R. Weeda, A. Kharat, B. Bookhart, W. L. Baker
Article
Emergency Medicine
Diana M. Sobieraj, Brandon K. Martinez, Benjamin Miao, Mark X. Cicero, Richard A. Kamin, Adrian Hernandez, Craig Coleman, William L. Baker
PREHOSPITAL EMERGENCY CARE
(2020)
Article
Cardiac & Cardiovascular Systems
Craig Coleman, William L. Baker, Anna-Katharina Meinecke, Daniel Eriksson, Brandon K. Martinez, Thomas J. Bunz, Mark J. Alberts
EUROPEAN HEART JOURNAL-CARDIOVASCULAR PHARMACOTHERAPY
(2020)
Article
Cardiac & Cardiovascular Systems
Benjamin Miao, Adrian V. Hernandez, Yuani M. Roman, Mark J. Alberts, Craig I. Coleman, William L. Baker
CLINICAL CARDIOLOGY
(2020)
Article
Hematology
Benjamin Miao, Nitesh Sood, Thomas J. Bunz, Craig Coleman
EUROPEAN JOURNAL OF HAEMATOLOGY
(2020)
Article
Multidisciplinary Sciences
Kevin Bowrin, Jean-Baptiste Briere, Laurent Fauchier, Craig Coleman, Aurelie Millier, Mondher Toumi, Emilie Clay, Pierre Levy
Article
Multidisciplinary Sciences
Tabassum Salam, Amy Duhig, Aarti A. Patel, Ann Cameron, Jennifer Voelker, Brahim Bookhart, Craig I. Coleman
Article
Cardiac & Cardiovascular Systems
Benjamin Miao, Adrian V. Hernandez, Mark J. Alberts, Nicholas Mangiafico, Yuani M. Roman, Craig I. Coleman
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2020)
Article
Pharmacology & Pharmacy
Tabassum Salam, Amy Duhig, Aarti A. Patel, Ann Cameron, Jennifer Voelker, Brahim Bookhart, Craig Coleman
CLINICAL THERAPEUTICS
(2020)
Article
Medicine, General & Internal
Olivia S. Costa, Jan Beyer-Westendorf, Veronica Ashton, Dejan Milentijevic, Kenneth Todd Moore, Thomas J. Bunz, Craig Coleman
CURRENT MEDICAL RESEARCH AND OPINION
(2020)
Article
Medicine, General & Internal
Craig Coleman, Stanley Thompson, Veronica Ashton, Michael Palladino, Thomas J. Bunz
JOURNAL OF THE NATIONAL MEDICAL ASSOCIATION
(2020)
Article
Hematology
Olivia S. Costa, Stanley Thompson, Veronica Ashton, Michael Palladino, Thomas J. Bunz, Craig Coleman
THROMBOSIS JOURNAL
(2020)