Reprogramming pancreatic stellate cells via p53 activation: A putative target for pancreatic cancer therapy
出版年份 2017 全文链接
标题
Reprogramming pancreatic stellate cells via p53 activation: A putative target for pancreatic cancer therapy
作者
关键词
Lipids, Fibroblasts, Cancer treatment, Lipid analysis, Cell cycle and cell division, Transcriptional control, Pancreatic cancer, RNA analysis
出版物
PLoS One
Volume 12, Issue 12, Pages e0189051
出版商
Public Library of Science (PLoS)
发表日期
2017-12-07
DOI
10.1371/journal.pone.0189051
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- The why, when and how of lipid droplet diversity
- (2017) Abdou Rachid Thiam et al. JOURNAL OF CELL SCIENCE
- Regulation of lipids is central to replicative senescence
- (2017) Darleny Y. Lizardo et al. Molecular BioSystems
- Cancer statistics, 2016
- (2016) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Mass spectrometry-based lipidomics analysis using methyl tert-butyl ether extraction in human hepatocellular carcinoma tissues
- (2015) Shuxia Jiang et al. Analytical Methods
- Meta- and Orthogonal Integration of Influenza “OMICs” Data Defines a Role for UBR4 in Virus Budding
- (2015) Shashank Tripathi et al. Cell Host & Microbe
- Expanding Roles for Lipid Droplets
- (2015) Michael A. Welte CURRENT BIOLOGY
- Combined CSL and p53 downregulation promotes cancer-associated fibroblast activation
- (2015) Maria-Giuseppina Procopio et al. NATURE CELL BIOLOGY
- Pancreatic cancer: The microenvironment needs attention too!
- (2015) M.V. Apte et al. PANCREATOLOGY
- p53 in the Myeloid Lineage Modulates an Inflammatory Microenvironment Limiting Initiation and Invasion of Intestinal Tumors
- (2015) Xue-Yan He et al. Cell Reports
- Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival
- (2014) Berna C. Özdemir et al. CANCER CELL
- Stromal Elements Act to Restrain, Rather Than Support, Pancreatic Ductal Adenocarcinoma
- (2014) Andrew D. Rhim et al. CANCER CELL
- Vitamin D Receptor-Mediated Stromal Reprogramming Suppresses Pancreatitis and Enhances Pancreatic Cancer Therapy
- (2014) Mara H. Sherman et al. CELL
- Tumor suppression in skin and other tissues via cross-talk between vitamin D- and p53-signaling
- (2014) Jörg Reichrath et al. Frontiers in Physiology
- Non-Cell-Autonomous Tumor Suppression by p53
- (2013) Amaia Lujambio et al. CELL
- Depletion of the novel p53-target gene carnitine palmitoyltransferase 1C delays tumor growth in the neurofibromatosis type I tumor model
- (2013) N Sanchez-Macedo et al. CELL DEATH AND DIFFERENTIATION
- Intramyocellular diacylglycerol concentrations and [U-13C]palmitate isotopic enrichment measured by LC/MS/MS
- (2013) Agnieszka U. Blachnio-Zabielska et al. JOURNAL OF LIPID RESEARCH
- Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer
- (2013) C. Feig et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Enzymatic Targeting of the Stroma Ablates Physical Barriers to Treatment of Pancreatic Ductal Adenocarcinoma
- (2012) Paolo P. Provenzano et al. CANCER CELL
- Apoptosis-induced mitochondrial dysfunction causes cytoplasmic lipid droplet formation
- (2012) J Boren et al. CELL DEATH AND DIFFERENTIATION
- The Pancreas Cancer Microenvironment
- (2012) C. Feig et al. CLINICAL CANCER RESEARCH
- Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer
- (2012) Michael A Jacobetz et al. GUT
- Persistent activation of pancreatic stellate cells creates a microenvironment favorable for the malignant behavior of pancreatic ductal adenocarcinoma
- (2012) Dong Tang et al. INTERNATIONAL JOURNAL OF CANCER
- Assays of plasma dehydrocholesteryl esters and oxysterols from Smith-Lemli-Opitz syndrome patients
- (2012) Wei Liu et al. JOURNAL OF LIPID RESEARCH
- The role of stroma in pancreatic cancer: diagnostic and therapeutic implications
- (2012) Mert Erkan et al. Nature Reviews Gastroenterology & Hepatology
- Mouse models of pancreatic cancer
- (2012) Marta Herreros-Villanueva WORLD JOURNAL OF GASTROENTEROLOGY
- Stat3/Socs3 Activation by IL-6 Transsignaling Promotes Progression of Pancreatic Intraepithelial Neoplasia and Development of Pancreatic Cancer
- (2011) Marina Lesina et al. CANCER CELL
- Retinoic Acid–Induced Pancreatic Stellate Cell Quiescence Reduces Paracrine Wnt–β-Catenin Signaling to Slow Tumor Progression
- (2011) Fieke E.M. Froeling et al. GASTROENTEROLOGY
- Carnitine palmitoyltransferase 1C promotes cell survival and tumor growth under conditions of metabolic stress
- (2011) K. Zaugg et al. GENES & DEVELOPMENT
- StellaTUM: current consensus and discussion on pancreatic stellate cell research
- (2011) Mert Erkan et al. GUT
- ROS-Mediated p53 Induction of Lpin1 Regulates Fatty Acid Oxidation in Response to Nutritional Stress
- (2011) Wissam Assaily et al. MOLECULAR CELL
- Deconstructing p53 transcriptional networks in tumor suppression
- (2011) Kathryn T. Bieging et al. TRENDS IN CELL BIOLOGY
- Catalytic, enantioselective synthesis of stilbene cis-diamines: A concise preparation of (−)-Nutlin-3, a potent p53/MDM2 inhibitor
- (2011) Tyler A. Davis et al. Chemical Science
- p53 Status in Stromal Fibroblasts Modulates Tumor Growth in an SDF1-Dependent Manner
- (2010) Y. Addadi et al. CANCER RESEARCH
- Stromal biology and therapy in pancreatic cancer
- (2010) A. Neesse et al. GUT
- 1,25-Dihydroxyvitamin D3 Enhances the Apoptotic Activity of MDM2 Antagonist Nutlin-3a in Acute Myeloid Leukemia Cells Expressing Wild-type p53
- (2010) T. Thompson et al. MOLECULAR CANCER THERAPEUTICS
- Pancreatic Stellate Cells Increase the Invasion of Human Pancreatic Cancer Cells through the Stromal Cell-Derived Factor-1/CXCR4 Axis
- (2010) Zhenjun Gao et al. PANCREATOLOGY
- Clonal Mutations in the Cancer-Associated Fibroblasts: The Case against Genetic Coevolution
- (2009) I. Campbell et al. CANCER RESEARCH
- Signal transduction in pancreatic stellate cells
- (2009) Atsushi Masamune et al. JOURNAL OF GASTROENTEROLOGY
- Prosaposin inhibits tumor metastasis via paracrine and endocrine stimulation of stromal p53 and Tsp-1
- (2009) S.-Y. Kang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer
- (2009) K. P. Olive et al. SCIENCE
- Involvement of stromal p53 in tumor-stroma interactions
- (2009) Jair Bar et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Pancreatic Stellate Cells: Partners in Crime with Pancreatic Cancer Cells
- (2008) A. Vonlaufen et al. CANCER RESEARCH
- Cancer-Associated Stromal Fibroblasts Promote Pancreatic Tumor Progression
- (2008) R. F. Hwang et al. CANCER RESEARCH
- No evidence of clonal somatic genetic alterations in cancer-associated fibroblasts from human breast and ovarian carcinomas
- (2008) Wen Qiu et al. NATURE GENETICS
- Cancer cells suppress p53 in adjacent fibroblasts
- (2008) J Bar et al. ONCOGENE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now