Analysis of peripheral B cells and autoantibodies against the anti-nicotinic acetylcholine receptor derived from patients with myasthenia gravis using single-cell manipulation tools

Hinge-deleted IgG4 blocker therapy for acetylcholine receptor myasthenia gravis in rhesus monkeys

(2017) Mario Losen et al.   Scientific Reports

Randomized Trial of Thymectomy in Myasthenia Gravis

(2016) Gil I. Wolfe et al.   NEW ENGLAND JOURNAL OF MEDICINE

Rituximab in refractory myasthenia gravis: a prospective, open-label study with long-term follow-up

(2016) Dustin Anderson et al.   Annals of Clinical and Translational Neurology

Detection of Acetylcholine Receptor Modulating Antibodies by Flow Cytometry

(2015) Bucky K. Lozier et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Serology in the 21st century: the molecular-level analysis of the serum antibody repertoire

(2015) Yariv Wine et al.   CURRENT OPINION IN IMMUNOLOGY

Standardization of the experimental autoimmune myasthenia gravis (EAMG) model by immunization of rats with Torpedo californica acetylcholine receptors — Recommendations for methods and experimental designs

(2015) Mario Losen et al.   EXPERIMENTAL NEUROLOGY

Single-cell technologies to study the immune system

(2015) Valentina Proserpio et al.   IMMUNOLOGY

Myasthenia gravis: a clinical-immunological update

(2015) Sophie Binks et al.   JOURNAL OF NEUROLOGY

Rapid isolation of dengue-neutralizing antibodies from single cell-sorted human antigen-specific memory B-cell cultures

(2015) Kara S. Cox et al.   mAbs

Single-cell analysis tools for drug discovery and development

(2015) James R. Heath et al.   NATURE REVIEWS DRUG DISCOVERY

Computational and analytical challenges in single-cell transcriptomics

(2015) Oliver Stegle et al.   NATURE REVIEWS GENETICS

Clonal heterogeneity of thymic B cells from early-onset myasthenia gravis patients with antibodies against the acetylcholine receptor

(2014) Kathleen Vrolix et al.   JOURNAL OF AUTOIMMUNITY

Myasthenia Gravis: Paradox versus paradigm in autoimmunity

(2014) Sonia Berrih-Aknin   JOURNAL OF AUTOIMMUNITY

Myasthenia gravis: A comprehensive review of immune dysregulation and etiological mechanisms

(2014) Sonia Berrih-Aknin et al.   JOURNAL OF AUTOIMMUNITY

Mining human antibody repertoires

(2014) Roger R. Beerli et al.   mAbs

Design, synthesis, and characterization of a 39 amino acid peptide mimic of the main immunogenic region of the Torpedo acetylcholine receptor

(2014) Vu B. Trinh et al.   MOLECULAR IMMUNOLOGY

The promise and challenge of high-throughput sequencing of the antibody repertoire

(2014) George Georgiou et al.   NATURE BIOTECHNOLOGY

In-depth determination and analysis of the human paired heavy- and light-chain antibody repertoire

(2014) Brandon J DeKosky et al.   NATURE MEDICINE

Direct Proof of the In Vivo Pathogenic Role of the AChR Autoantibodies from Myasthenia Gravis Patients

(2014) Gregory Kordas et al.   PLoS One

Identification and characterization of the constituent human serum antibodies elicited by vaccination

(2014) Jason J. Lavinder et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pathophysiology of myasthenia gravis with antibodies to the acetylcholine receptor, muscle-specific kinase and low-density lipoprotein receptor-related protein 4

(2013) Jan J.G.M. Verschuuren et al.   AUTOIMMUNITY REVIEWS

Pathogenic immune mechanisms at the neuromuscular synapse: the role of specific antibody-binding epitopes in myasthenia gravis

(2013) M. G. Huijbers et al.   JOURNAL OF INTERNAL MEDICINE

Disturbed B cell subpopulations and increased plasma cells in myasthenia gravis patients

(2013) Siegfried Kohler et al.   JOURNAL OF NEUROIMMUNOLOGY

Targeting therapy to the neuromuscular junction: Proof of concept

(2013) Linda L. Kusner et al.   MUSCLE & NERVE

Plasmablasts as Migratory IgG-Producing Cells in the Pathogenesis of Neuromyelitis Optica

(2013) Norio Chihara et al.   PLoS One

Single-Cell Metabolomics: Analytical and Biological Perspectives

(2013) R. Zenobi   SCIENCE

Myasthenogenicity of the main immunogenic region

(2012) Jon Lindstrom et al.   Annals of the New York Academy of Sciences

Rapid production of antigen-specific monoclonal antibodies from a variety of animals

(2012) Nobuyuki Kurosawa et al.   BMC BIOLOGY

Antibodies against the main immunogenic region of the acetylcholine receptor correlate with disease severity in myasthenia gravis

(2012) Tomoko Masuda et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Anti-Aquaporin-4 monoclonal antibody blocker therapy for neuromyelitis optica

(2011) Lukmanee Tradtrantip et al.   ANNALS OF NEUROLOGY

Target-selective joint polymerase chain reaction: A robust and rapid method for high-throughput production of recombinant monoclonal antibodies from single cells

(2011) Megumi Yoshioka et al.   BMC BIOTECHNOLOGY

Isolation of a Human Anti-HIV gp41 Membrane Proximal Region Neutralizing Antibody by Antigen-Specific Single B Cell Sorting

(2011) Lynn Morris et al.   PLoS One

Different B Cell Populations Mediate Early and Late Memory During an Endogenous Immune Response

(2011) K. A. Pape et al.   SCIENCE

Homologous regions of autoantibody heavy chain complementarity-determining region 3 (H-CDR3) in patients with pemphigus cause pathogenicity

(2010) Jun Yamagami et al.   JOURNAL OF CLINICAL INVESTIGATION

Different interaction between tricyclic antidepressants and mecamylamine with the human α3β4 nicotinic acetylcholine receptor ion channel

(2010) Hugo R. Arias et al.   NEUROCHEMISTRY INTERNATIONAL

AlphaLISA Immunoassay Platform— The “No-Wash” High-Throughput Alternative to ELISA

(2009) Martina Bielefeld-Sevigny   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Main Immunogenic Region Structure Promotes Binding of Conformation-Dependent Myasthenia Gravis Autoantibodies, Nicotinic Acetylcholine Receptor Conformation Maturation, and Agonist Sensitivity

(2009) J. Luo et al.   JOURNAL OF NEUROSCIENCE

A rapid and efficient single-cell manipulation method for screening antigen-specific antibody–secreting cells from human peripheral blood

(2009) Aishun Jin et al.   NATURE MEDICINE

Mammalian Nicotinic Acetylcholine Receptors: From Structure to Function

(2009) Edson X. Albuquerque et al.   PHYSIOLOGICAL REVIEWS

Myasthenia Gravis and the Tops and Bottoms of AChRs

(2008) Jon Lindstrom et al.   Annals of the New York Academy of Sciences

Lifetime course of myasthenia gravis

(2007) David Grob et al.   MUSCLE & NERVE