Early-onset behavioral and neurochemical deficits in the genetic mouse model of phenylketonuria

Therapeutic brain modulation with targeted large neutral amino acid supplements in the Pah-enu2 phenylketonuria mouse model

(2016) Danique van Vliet et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Glycomacropeptide for nutritional management of phenylketonuria: a randomized, controlled, crossover trial

(2016) Denise M Ney et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Evaluation of Tetrahydrobiopterin Therapy with Large Neutral Amino Acid Supplementation in Phenylketonuria: Effects on Potential Peripheral Biomarkers, Melatonin and Dopamine, for Brain Monoamine Neurotransmitters

(2016) Shoji Yano et al.   PLoS One

Alternative therapies to address the unmet medical needs of patients with phenylketonuria

(2015) Nenad Blau et al.   EXPERT OPINION ON PHARMACOTHERAPY

Erythrocyte-mediated delivery of phenylalanine ammonia lyase for the treatment of phenylketonuria in BTBR-Pahenu2 mice

(2014) Luigia Rossi et al.   JOURNAL OF CONTROLLED RELEASE

The effects of sapropterin on urinary monoamine metabolites in phenylketonuria

(2013) Teresa D. Douglas et al.   MOLECULAR GENETICS AND METABOLISM

Behavioral and Neurochemical Characterization of New Mouse Model of Hyperphenylalaninemia

(2013) Tiziana Pascucci et al.   PLoS One

In vivo catecholaminergic metabolism in the medial prefrontal cortex of ENU2 mice: an investigation of the cortical dopamine deficit in phenylketonuria

(2012) Tiziana Pascucci et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Optimising growth in phenylketonuria: Current state of the clinical evidence base

(2011) Katharina Dokoupil et al.   CLINICAL NUTRITION

5-Hydroxytryptophan during critical postnatal period improves cognitive performances and promotes dendritic spine maturation in genetic mouse model of phenylketonuria

(2010) Diego Andolina et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Early behavioural markers of disease in P301S tau transgenic mice

(2009) Maria Luisa Scattoni et al.   BEHAVIOURAL BRAIN RESEARCH

Comparison of Adeno-Associated Virus Pseudotype 1, 2, and 8 Vectors Administered by Intramuscular Injection in the Treatment of Murine Phenylketonuria

(2009) Alexandre Rebuffat et al.   HUMAN GENE THERAPY

5-Hydroxytryptophan rescues serotonin response to stress in prefrontal cortex of hyperphenylalaninaemic mice

(2009) Tiziana Pascucci et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Pathogenesis of cognitive dysfunction in phenylketonuria: Review of hypotheses☆

(2009) M.J. de Groot et al.   MOLECULAR GENETICS AND METABOLISM

Animal models of brain dysfunction in phenylketonuria☆

(2009) A.E. Martynyuk et al.   MOLECULAR GENETICS AND METABOLISM

Reduced availability of brain amines during critical phases of postnatal development in a genetic mouse model of cognitive delay

(2008) Tiziana Pascucci et al.   BRAIN RESEARCH

Twenty-Five Years of Research on Neurocognitive Outcomes in Early-Treated Phenylketonuria: Intelligence and Executive Function

(2008) Kathryn DeRoche et al.   DEVELOPMENTAL NEUROPSYCHOLOGY

Unusual Repertoire of Vocalizations in the BTBR T+tf/J Mouse Model of Autism

(2008) Maria Luisa Scattoni et al.   PLoS One