Toll-like receptor 9 suppresses lupus disease in Fas-sufficient MRL Mice

Dendritic Cells Regulate Extrafollicular Autoreactive B Cells via T Cells Expressing Fas and Fas Ligand

(2016) Michelle L. Ols et al.   IMMUNITY

TLR9 Deficiency Leads to Accelerated Renal Disease and Myeloid Lineage Abnormalities in Pristane-Induced Murine Lupus

(2016) Lukas Bossaller et al.   JOURNAL OF IMMUNOLOGY

Toll-like receptors and chronic inflammation in rheumatic diseases: new developments

(2016) Leo A. B. Joosten et al.   Nature Reviews Rheumatology

Genetics and novel aspects of therapies in systemic lupus erythematosus

(2015) Manfred Relle et al.   AUTOIMMUNITY REVIEWS

Cell-Intrinsic Expression of TLR9 in Autoreactive B Cells Constrains BCR/TLR7-Dependent Responses

(2015) Kerstin Nündel et al.   JOURNAL OF IMMUNOLOGY

Autoimmune Lymphoproliferative Syndrome: an Update and Review of the Literature

(2014) Shaili Shah et al.   CURRENT ALLERGY AND ASTHMA REPORTS

Double Negative (DN) αβ T Cells: misperception and overdue recognition

(2014) Maria N Martina et al.   IMMUNOLOGY AND CELL BIOLOGY

Genetic evidence for the role of plasmacytoid dendritic cells in systemic lupus erythematosus

(2014) Vanja Sisirak et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Programmed Death Ligand 1 Regulates a Critical Checkpoint for Autoimmune Myocarditis and Pneumonitis in MRL Mice

(2014) J. A. Lucas et al.   JOURNAL OF IMMUNOLOGY

Opposing Impact of B Cell-Intrinsic TLR7 and TLR9 Signals on Autoantibody Repertoire and Systemic Inflammation

(2014) S. W. Jackson et al.   JOURNAL OF IMMUNOLOGY

Activation of Rheumatoid Factor–Specific B Cells Is Antigen Dependent and Occurs Preferentially Outside of Germinal Centers in the Lupus-Prone NZM2410 Mouse Model

(2014) Allison Sang et al.   JOURNAL OF IMMUNOLOGY

B Cell–Intrinsic TLR7 Signaling Is Essential for the Development of Spontaneous Germinal Centers

(2014) Chetna Soni et al.   JOURNAL OF IMMUNOLOGY

TLR8 on dendritic cells and TLR9 on B cells restrain TLR7-mediated spontaneous autoimmunity in C57BL/6 mice

(2014) B. Desnues et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Life in the Fas lane: differential outcomes of Fas signaling

(2013) Elizabeth Brint et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Expression of an anti-RNA autoantibody in a mouse model of SLE increases neutrophil and monocyte numbers as well as IFN-I expression

(2013) Jin-Hwan Han et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Signals via the Adaptor MyD88 in B Cells and DCs Make Distinct and Synergistic Contributions to Immune Activation and Tissue Damage in Lupus

(2013) Lino L. Teichmann et al.   IMMUNITY

B-lymphocyte tolerance and effector function in immunity and autoimmunity

(2013) Wasif N. Khan et al.   IMMUNOLOGIC RESEARCH

TLR9 Promotes Tolerance by Restricting Survival of Anergic Anti-DNA B Cells, Yet Is Also Required for Their Activation

(2013) K. M. Nickerson et al.   JOURNAL OF IMMUNOLOGY

Exacerbated Autoimmunity in the Absence of TLR9 in MRL.Faslpr Mice Depends on Ifnar1

(2013) K. M. Nickerson et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Type I IFN Drives Emergency Myelopoiesis and Peripheral Myeloid Expansion during Chronic TLR7 Signaling

(2013) M. B. Buechler et al.   JOURNAL OF IMMUNOLOGY

Contributions of B cells to lupus pathogenesis

(2013) Allison Sang et al.   MOLECULAR IMMUNOLOGY

Toll-Like Receptor 2 or Toll-Like Receptor 4 Deficiency Does Not Modify Lupus in MRLlpr Mice

(2013) Simon J. Freeley et al.   PLoS One

TLR7 and TLR9 in SLE: when sensing self goes wrong

(2012) T. Celhar et al.   IMMUNOLOGIC RESEARCH

B Cell TLR7 Expression Drives Anti-RNA Autoantibody Production and Exacerbates Disease in Systemic Lupus Erythematosus-Prone Mice

(2012) S.-H. Hwang et al.   JOURNAL OF IMMUNOLOGY

Dual signaling by innate and adaptive immune receptors is required for TLR7-induced B-cell-mediated autoimmunity

(2012) E. R. Walsh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CD3+CD4−CD8− (double negative) T cells: Saviours or villains of the immune response?

(2011) Fulvio D’Acquisto et al.   BIOCHEMICAL PHARMACOLOGY

B cells and autoimmunity

(2011) Shiv Pillai et al.   CURRENT OPINION IN IMMUNOLOGY

Unc93B1 Restricts Systemic Lethal Inflammation by Orchestrating Toll-like Receptor 7 and 9 Trafficking

(2011) Ryutaro Fukui et al.   IMMUNITY

TLR9 in Peritoneal B-1b Cells Is Essential for Production of Protective Self-Reactive IgM To Control Th17 Cells and Severe Autoimmunity

(2011) A. D. Stoehr et al.   JOURNAL OF IMMUNOLOGY

Facultative role for T cells in extrafollicular Toll-like receptor-dependent autoreactive B-cell responses in vivo

(2011) R. A. Sweet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A new site-directed transgenic rheumatoid factor mouse model demonstrates extrafollicular class switch and plasmablast formation

(2010) Rebecca A. Sweet et al.   AUTOIMMUNITY

TLR9 and TLR4 are required for the development of autoimmunity and lupus nephritis in pristane nephropathy

(2010) S.A. Summers et al.   JOURNAL OF AUTOIMMUNITY

TLR9 Regulates TLR7- and MyD88-Dependent Autoantibody Production and Disease in a Murine Model of Lupus

(2010) Kevin M. Nickerson et al.   JOURNAL OF IMMUNOLOGY

The Many Roles of FAS Receptor Signaling in the Immune System

(2009) Andreas Strasser et al.   IMMUNITY

Critical role of TLR7 in the acceleration of systemic lupus erythematosus in TLR9-deficient mice

(2009) Marie-Laure Santiago-Raber et al.   JOURNAL OF AUTOIMMUNITY

Critical Role of TLR2 and TLR4 in Autoantibody Production and Glomerulonephritis in lpr Mutation-Induced Mouse Lupus

(2009) A. Lartigue et al.   JOURNAL OF IMMUNOLOGY

Endosomal TLR signaling is required for anti-nucleic acid and rheumatoid factor autoantibodies in lupus

(2009) D. H. Kono et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sites and Stages of Autoreactive B Cell Activation and Regulation

(2008) Mark J. Shlomchik   IMMUNITY

TLR7-dependent and FcγR-independent production of type I interferon in experimental mouse lupus

(2008) Pui Y. Lee et al.   JOURNAL OF EXPERIMENTAL MEDICINE