Structural and Functional Elucidation of Yeast Lanosterol 14α-Demethylase in Complex with Agrochemical Antifungals

Triazole resistance mediated by mutations of a conserved active site tyrosine in fungal lanosterol 14α-demethylase

(2016) Alia A. Sagatova et al.   Scientific Reports

Structural Insights into Binding of the Antifungal Drug Fluconazole to Saccharomyces cerevisiae Lanosterol 14α-Demethylase

(2015) Alia A. Sagatova et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Novel Substrate Specificity and Temperature-Sensitive Activity of Mycosphaerella graminicola CYP51 Supported by the Native NADPH Cytochrome P450 Reductase

(2015) Claire L. Price et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Azole Resistance inAspergillus fumigatus: Can We Retain the Clinical Use of Mold-Active Antifungal Azoles?

(2015) Paul E. Verweij et al.   CLINICAL INFECTIOUS DISEASES

Quantification ofAspergillus fumigatusand enteric bacteria in European compost and biochar

(2015) Selma Franceschini et al.   COMPOST SCIENCE & UTILIZATION

Occurrence, fate and ecological risk of five typical azole fungicides as therapeutic and personal care products in the environment: A review

(2015) Zhi-Feng Chen et al.   ENVIRONMENT INTERNATIONAL

Structure-Functional Characterization of Cytochrome P450 Sterol 14α-Demethylase (CYP51B) fromAspergillus fumigatusand Molecular Basis for the Development of Antifungal Drugs

(2015) Tatiana Y. Hargrove et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Azole fungicides - understanding resistance mechanisms in agricultural fungal pathogens

(2015) Claire L Price et al.   PEST MANAGEMENT SCIENCE

Architecture of a single membrane spanning cytochrome P450 suggests constraints that orient the catalytic domain relative to a bilayer

(2014) B. C. Monk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aspergillosis due to Voriconazole Highly Resistant Aspergillus fumigatus and Recovery of Genetically Related Resistant Isolates From Domiciles

(2013) Jan W. M. van der Linden et al.   CLINICAL INFECTIOUS DISEASES

Chiral Triazole Fungicide Difenoconazole: Absolute Stereochemistry, Stereoselective Bioactivity, Aquatic Toxicity, and Environmental Behavior in Vegetables and Soil

(2013) Fengshou Dong et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Environmental fungicides and triazole resistance inAspergillus

(2013) Paul Bowyer et al.   PEST MANAGEMENT SCIENCE

Emergence of Azole-Resistant Aspergillus fumigatus Strains due to Agricultural Azole Use Creates an Increasing Threat to Human Health

(2013) Anuradha Chowdhary et al.   PLoS Pathogens

Prothioconazole and Prothioconazole-Desthio Activities against Candida albicans Sterol 14-α-Demethylase

(2012) Josie E. Parker et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Fungal cytochrome P450 sterol 14α-demethylase (CYP51) and azole resistance in plant and human pathogens

(2012) Rayko Becher et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Molecular Epidemiology of Aspergillus fumigatus Isolates Harboring the TR34/L98H Azole Resistance Mechanism

(2012) S. M. T. Camps et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Update on mechanisms of azole resistance inMycosphaerella graminicolaand implications for future control

(2012) Hans J Cools et al.   PEST MANAGEMENT SCIENCE

Triazole Fungicides Can Induce Cross-Resistance to Medical Triazoles in Aspergillus fumigatus

(2012) Eveline Snelders et al.   PLoS One

iMOSFLM: a new graphical interface for diffraction-image processing withMOSFLM

(2011) T. Geoff G. Battye et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

The structure–function relationship of the Aspergillus fumigatus cyp51A L98H conversion by site-directed mutagenesis: The mechanism of L98H azole resistance

(2011) Eveline Snelders et al.   FUNGAL GENETICS AND BIOLOGY

Molecular Modelling of the Emergence of Azole Resistance in Mycosphaerella graminicola

(2011) Jonathan G. L. Mullins et al.   PLoS One

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Expression, Purification, and Characterization of Aspergillus fumigatus Sterol 14-  Demethylase (CYP51) Isoenzymes A and B

(2010) A. G. S. Warrilow et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Mechanism of Binding of Prothioconazole toMycosphaerella graminicolaCYP51 Differs from That of Other Azole Antifungals

(2010) Josie E. Parker et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Endocrine Profiling and Prioritization of Environmental Chemicals Using ToxCast Data

(2010) David M. Reif et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Endocrine disrupting effects in vitro of conazole antifungals used as pesticides and pharmaceuticals

(2010) Mia B. Kjærstad et al.   REPRODUCTIVE TOXICOLOGY

Measurement of cytochrome P450 and NADPH–cytochrome P450 reductase

(2009) F Peter Guengerich et al.   Nature Protocols

Frequency of different CYP51-haplotypes of Mycosphaerella graminicola and their impact on epoxiconazole-sensitivity and -field efficacy

(2008) G. Stammler et al.   CROP PROTECTION