Progesterone Attenuates Microglial-Driven Retinal Degeneration and Stimulates Protective Fractalkine-CX3CR1 Signaling
出版年份 2016 全文链接
标题
Progesterone Attenuates Microglial-Driven Retinal Degeneration and Stimulates Protective Fractalkine-CX3CR1 Signaling
作者
关键词
Microglial cells, Retina, Photoreceptors, Diet, Cell death, Mouse models, Neuronal death, Progesterone
出版物
PLoS One
Volume 11, Issue 11, Pages e0165197
出版商
Public Library of Science (PLoS)
发表日期
2016-11-05
DOI
10.1371/journal.pone.0165197
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- The synthetic progesterone Norgestrel is neuroprotective in stressed photoreceptor-like cells and retinal explants, mediating its effects via basic fibroblast growth factor, protein kinase A and glycogen synthase kinase 3β signalling
- (2016) Alice C. Wyse Jackson et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Microglial phagocytosis and activation underlying photoreceptor degeneration is regulated by CX3CL1-CX3CR1 signaling in a mouse model of retinitis pigmentosa
- (2016) Matthew K. Zabel et al. GLIA
- Alterations to retinal architecture prior to photoreceptor loss in a mouse model of retinitis pigmentosa
- (2016) Sarah L. Roche et al. INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY
- Disruption of Fractalkine Signaling Leads to Microglial Activation and Neuronal Damage in the Diabetic Retina
- (2015) Sandra M. Cardona et al. ASN Neuro
- Microglial phagocytosis of living photoreceptors contributes to inherited retinal degeneration
- (2015) L. Zhao et al. EMBO Molecular Medicine
- Progesterone receptor signalling in retinal photoreceptor neuroprotection
- (2015) Alice C. Wyse Jackson et al. JOURNAL OF NEUROCHEMISTRY
- Time-dependent effects of CX3CR1 in a mouse model of mild traumatic brain injury
- (2015) Heidi Y. Febinger et al. Journal of Neuroinflammation
- Chemokine-mediated inflammation in the degenerating retina is coordinated by Müller cells, activated microglia, and retinal pigment epithelium
- (2015) Matt Rutar et al. Journal of Neuroinflammation
- Targeting translocator protein (18 kDa) (TSPO) dampens pro-inflammatory microglia reactivity in the retina and protects from degeneration
- (2015) Rebecca Scholz et al. Journal of Neuroinflammation
- Minocycline counter-regulates pro-inflammatory microglia responses in the retina and protects from degeneration
- (2015) Rebecca Scholz et al. Journal of Neuroinflammation
- Contribution of Microglia-Mediated Neuroinflammation to Retinal Degenerative Diseases
- (2015) Maria H. Madeira et al. MEDIATORS OF INFLAMMATION
- Neuronal Cx3cr1 Deficiency Protects against Amyloid β-Induced Neurotoxicity
- (2015) Jenny Dworzak et al. PLoS One
- Adalimumab Reduces Photoreceptor Cell Death in A Mouse Model of Retinal Degeneration
- (2015) Cristina Martínez-Fernández de la Cámara et al. Scientific Reports
- Fractalkine receptor regulates microglial neurotoxicity in an experimental mouse glaucoma model
- (2014) Ke Wang et al. GLIA
- Cutting Edge: IL-1α Is a Crucial Danger Signal Triggering Acute Myocardial Inflammation during Myocardial Infarction
- (2014) Jérôme Lugrin et al. JOURNAL OF IMMUNOLOGY
- Translocator protein (18 kDa) (TSPO) is expressed in reactive retinal microglia and modulates microglial inflammation and phagocytosis
- (2014) Marcus Karlstetter et al. Journal of Neuroinflammation
- Suppression of Microglial Activation Is Neuroprotective in a Mouse Model of Human Retinitis Pigmentosa
- (2014) B. Peng et al. JOURNAL OF NEUROSCIENCE
- Macroglia-Microglia Interactions via TSPO Signaling Regulates Microglial Activation in the Mouse Retina
- (2014) M. Wang et al. JOURNAL OF NEUROSCIENCE
- Microglial NADPH oxidase activation mediates rod cell death in the retinal degeneration in rd mice
- (2014) H. Zeng et al. NEUROSCIENCE
- CX3CL1 (Fractalkine) Protein Expression in Normal and Degenerating Mouse Retina: In Vivo Studies
- (2014) Marina Zieger et al. PLoS One
- Suppressed pro-inflammatory response of microglia in CX3CR1 knockout mice
- (2013) Hayley A. Mattison et al. JOURNAL OF NEUROIMMUNOLOGY
- Total Protein Analysis as a Reliable Loading Control for Quantitative Fluorescent Western Blotting
- (2013) Samantha L. Eaton et al. PLoS One
- Minocycline selectively inhibits M1 polarization of microglia
- (2013) K Kobayashi et al. Cell Death & Disease
- Activation of survival pathways in the degenerating retina of rd10 mice
- (2012) Marijana Samardzija et al. EXPERIMENTAL EYE RESEARCH
- Knockout of ccr2 alleviates photoreceptor cell death in a model of retinitis pigmentosa
- (2012) Congrong Guo et al. EXPERIMENTAL EYE RESEARCH
- Laboratory Evidence of Sustained Chronic Inflammatory Reaction in Retinitis Pigmentosa
- (2012) Noriko Yoshida et al. OPHTHALMOLOGY
- Role of Fractalkine/CX3CR1 Interaction in Light-Induced Photoreceptor Degeneration through Regulating Retinal Microglial Activation and Migration
- (2012) Meng Zhang et al. PLoS One
- An ADIOL-ERβ-CtBP Transrepression Pathway Negatively Regulates Microglia-Mediated Inflammation
- (2011) Kaoru Saijo et al. CELL
- Enhancing survival of photoreceptor cells in vivo using the synthetic progestin Norgestrel
- (2011) Francesca Doonan et al. JOURNAL OF NEUROCHEMISTRY
- Microglia in the healthy and degenerating retina: Insights from novel mouse models
- (2010) Marcus Karlstetter et al. IMMUNOBIOLOGY
- Inflammation in neurodegenerative diseases
- (2010) Sandra Amor et al. IMMUNOLOGY
- Constitutive Endocytosis of the Chemokine CX3CL1 Prevents Its Degradation by Cell Surface Metalloproteases
- (2009) Yi-Wei Huang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Fractalkine-induced activation of the phosphatidylinositol-3 kinase pathway attentuates microglial activationin vivoandin vitro
- (2009) Anthony Lyons et al. JOURNAL OF NEUROCHEMISTRY
- CCL2 is a key mediator of microglia activation in neuropathic pain states
- (2008) Michael A. Thacker et al. EUROPEAN JOURNAL OF PAIN
- Analyzing real-time PCR data by the comparative CT method
- (2008) Thomas D Schmittgen et al. Nature Protocols
- Functional and structural modifications during retinal degeneration in the rd10 mouse
- (2008) R. Barhoum et al. NEUROSCIENCE
- Microglial clearance function in health and disease
- (2008) I. Napoli et al. NEUROSCIENCE
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