RGS10 Negatively Regulates Platelet Activation and Thrombogenesis

CXCL12 regulates platelet activation via the regulator of G-protein signaling 16

(2016) Zubair A. Karim et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Directly Activating the Integrin αIIbβ3 Initiates Outside-In Signaling by Causing αIIbβ3 Clustering

(2016) Karen P. Fong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

R4 Regulator of G Protein Signaling (RGS) Proteins in Inflammation and Immunity

(2015) Zhihui Xie et al.   AAPS Journal

Characterization of a Novel Function-Blocking Antibody Targeted Against the Platelet P2Y1ReceptorSignificance

(2015) Zubair A. Karim et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The regulator of G-protein signaling 18 regulates platelet aggregation, hemostasis and thrombosis

(2015) Fatima Z. Alshbool et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A review of platelet secretion assays for the diagnosis of inherited platelet secretion disorders

(2015) Andrew D. Mumford et al.   THROMBOSIS AND HAEMOSTASIS

Synergistic effect of signaling from receptors of soluble platelet agonists and outside-in signaling in formation of a stable fibrinogen-integrin αIIbβ3-actin cytoskeleton complex

(2015) Ivan Budnik et al.   THROMBOSIS RESEARCH

A Critical Role for the Transient Receptor Potential Channel Type 6 in Human Platelet Activation

(2015) Hari Priya Vemana et al.   PLoS One

The Antidepressant 5-HT2A Receptor Antagonists Pizotifen and Cyproheptadine Inhibit Serotonin-Enhanced Platelet Function

(2014) Olivia A. Lin et al.   PLoS One

Regulator of G-Protein Signaling 18 Controls Both Platelet Generation and Function

(2014) Nathalie Delesque-Touchard et al.   PLoS One

Allosteric and Biased G Protein-Coupled Receptor Signaling Regulation: Potentials for New Therapeutics

(2014) Etienne Khoury et al.   Frontiers in Endocrinology

On the Activation of Integrin αIIbβ3: Outside-in and Inside-out Pathways

(2013) Mehrdad Mehrbod et al.   BIOPHYSICAL JOURNAL

I B kinase phosphorylation of SNAP-23 controls platelet secretion

(2013) Z. A. Karim et al.   BLOOD

Critical Role of Regulator G-Protein Signaling 10 (RGS10) in Modulating Macrophage M1/M2 Activation

(2013) Jae-Kyung Lee et al.   PLoS One

Molecular Alliance-From Orthosteric and Allosteric Ligands to Dualsteric/Bitopic Agonists at G Protein Coupled Receptors

(2012) Klaus Mohr et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A novel antibody targeting the ligand binding domain of the thromboxane A2 receptor exhibits antithrombotic properties in vivo

(2012) John P. Murad et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Orthosteric versus allosteric GPCR activation: The great challenge of group-III mGluRs

(2012) Peter J. Flor et al.   BIOCHEMICAL PHARMACOLOGY

Regulators of G protein signaling: role in hematopoiesis, megakaryopoiesis and platelet function

(2012) S. LOUWETTE et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

A newly identified complex of spinophilin and the tyrosine phosphatase, SHP-1, modulates platelet activation by regulating G protein-dependent signaling

(2011) P. Ma et al.   BLOOD

Regulator of G-Protein Signaling-10 Negatively Regulates NF- B in Microglia and Neuroprotects Dopaminergic Neurons in Hemiparkinsonian Rats

(2011) J.-K. Lee et al.   JOURNAL OF NEUROSCIENCE

RGS2 deficiency in mice does not affect platelet thrombus formation at sites of vascular injury

(2011) F. BANNO et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

RGS/Gi2  interactions modulate platelet accumulation and thrombus formation at sites of vascular injury

(2010) R. S. Signarvic et al.   BLOOD

Thinking Outside of the "RGS Box": New Approaches to Therapeutic Targeting of Regulators of G Protein Signaling

(2010) B. Sjogren et al.   MOLECULAR PHARMACOLOGY

Regulator of G-Protein Signaling 10 Promotes Dopaminergic Neuron Survival via Regulation of the Microglial Inflammatory Response

(2008) J.-K. Lee et al.   JOURNAL OF NEUROSCIENCE