Article
Chemistry, Physical
Fangya Li, Ying Wang, Jianyu Zhang
Summary: This study investigates the influence of ferrous ammonium sulfate concentration on the kinetic isotope effect (KIE) of a chemical demethylation system, revealing the mechanism and key steps of this process. The results suggest that the initial hydrogen extraction is the rate-limiting step, and a tight transition state structure is observed through the analysis of KIE trends.
JOURNAL OF CHEMICAL PHYSICS
(2023)
Review
Engineering, Environmental
Hanping Pan, Yuan Gao, Ning Li, Yang Zhou, Qintie Lin, Jin Jiang
Summary: Bicarbonate activated hydrogen peroxide oxidation system (BAP system) has shown excellent performance in water treatment under neutral or weak alkaline conditions. The high reactivity of HCO4- and its collaboration with various reactive species facilitate direct oxidation of pollutants. Moreover, HCO3- in the BAP system exhibits multiple functions to stabilize reactions and prolong the catalyst's lifetime.
CHEMICAL ENGINEERING JOURNAL
(2021)
Article
Environmental Sciences
Nestor A. Urbina-Suarez, Christian Rivera-Caicedo, Angel Dario Gonzalez-Delgado, Andres F. Barajas-Solano, Fiderman Machuca-Martinez
Summary: The research focuses on the use of advanced oxidation process (AOPs) with hydrogen peroxide (H2O2) and sodium bicarbonate (NaHCO3) for the treatment of tannery wastewater. The optimal process conditions for removing different compounds were found to be NaHCO3 1 M, H2O2 2 M, and 60 degrees C, with high removal efficiencies for color and ammoniacal nitrogen. This study concludes that AOPs using H2O2 and NaHCO3 are recommended for effective removal of color and ammoniacal nitrogen in tannery wastewater.
Article
Chemistry, Physical
Huijie Dong, Xianjie Feng, Yu Guo, Zihui Jia, Xueying Zhang, Aihua Xu, Xiaoxia Li
Summary: The cobalt nanoparticles encapsulated in nitrogen-doped carbon nanotubes, as a novel catalyst, showed excellent catalytic performance for acid orange 7 degradation in the bicarbonate-activated hydrogen peroxide system. It exhibited high stability against cobalt ions leaching and proposed a activation mechanism with superoxide ion and single oxygen as the dominant reactive species from H2O2 decomposition by the synergistic effect of Co(0) and N species.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2021)
Article
Chemistry, Organic
Erik Schroeter, Philip Rohland, Kristin Schreyer, Christian Friebe, Martin D. Hager, Ulrich S. Schubert
Summary: This study thoroughly investigates different oxidation processes for one-step synthesis of N-oxyl radicals. The determining parameter for reaction yield is determined by redox titration and electron spin resonance spectroscopy. The most promising procedures have been applied to polymeric materials to evaluate the feasibility of catalysts for more complex substrates.
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Chemistry, Applied
Natalia Llopis, Patricia Gisbert, Alejandro Baeza, Jara Correa-Campillo
Summary: This study describes the oxidative dehydrogenation of N-heterocyclic compounds using H2O2 as an oxidant in combination with polar solvents such as 1,1,1,3,3,3-hexafluoroisopropanol (HFIP) and H2O. The best yields for heteroaromatic compounds were generally achieved in HFIP, but it is surprising that using a non-toxic solvent like H2O also gave good yields. Additionally, this method can be implemented on a larger scale and the HFIP solvent can be reused.
ADVANCED SYNTHESIS & CATALYSIS
(2022)
Article
Engineering, Environmental
Ya Wu, Rongmiao Fang, Hao Li, Jingyao Li, Dan Zhao, NaNa Chang, Huaming Sun, Jun Shi
Summary: This study developed an efficient degradation method for PAEs using a combination of PS and H2O2 activated by Fe2+ ions, which showed high removal efficiency, low oxidant dosage, and a wide pH range. The synergistic effect of PS and H2O2 in the Fe2+-containing system improved the degradation efficiency of PAEs.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Engineering, Electrical & Electronic
YiQian Li, JiaLin Liu, Feng Zhao, Ke Song, LanLan Nie, DaWei Liu, XinPei Lu
Summary: Ethanol solution is widely used as a disinfectant, but only has significant bactericidal capability at a volume fraction of around 70%-75%. Higher concentrations are irritating while lower concentrations are less effective. This study proposes a plasma-activated low-concentration ethanol solution (PAES) as a green, efficient and less irritating disinfectant.
Article
Engineering, Environmental
Lu Wang, Ke Jing, Baowei Hu, Junhe Lu
Summary: The formation of halogenated oxidation by-products in sulfate radical based advanced oxidation process has raised concerns. Addition of hydrogen peroxide can significantly suppress the generation of halogenated-OBPs, but the formation of organic bromines is still a concern.
CHEMICAL ENGINEERING JOURNAL
(2021)
Article
Chemistry, Analytical
Wenzhi Zhang, Shuzhen Li, Ani Zhou, Maoguo Li
Summary: Nucleic acid detection is crucial for genetic disease diagnosis, cancer treatment, and infectious disease prevention. However, current methods based on biological amplification are complex and time-consuming. In this study, a simple and rapid nucleic acid assay using chemical cyclic amplification was developed. The Fenton-HA system, which continuously generates hydroxyl radicals via Fe3+/Fe2+ cycle, was introduced for the detection of Fe3+. The method showed good sensitivity and could be used for the detection of HIV-DNA and miRNA-21 with low limits of detection.
ANALYTICAL CHEMISTRY
(2023)
Article
Materials Science, Biomaterials
Gang Wu, Bao Jiang, Lin Zhou, Ao Wang, Shaohua Wei
Summary: The study utilizes activated carbon nanoparticles (ANs) derived from coconut shell to exhibit peroxidase-mimic nanoenzyme activity for chemodynamic therapy (CDT) in cancer treatment. The PANs also show efficient photothermal conversion efficiency for photothermal therapy (PTT), with heating effect enhancing peroxidase-mimic activity, achieving a synergistic PTT-CDT therapeutic outcome. Additionally, Gd@PANs can be used for T1-magnetic resonance imaging (MRI) of tumors, integrating treatment and diagnosis.
JOURNAL OF MATERIALS CHEMISTRY B
(2021)
Article
Chemistry, Physical
Gabriela Biliuta, Raluca Ioana Baron, Sergiu Coseri
Summary: In this study, a green method was used to oxidize pullulan in an alkaline medium. The resulting oxidized pullulans were characterized using various techniques. It was found that the reaction time affected the carboxyl group content in the oxidized pullulans. The oxidation reaction had a fast rate in the first 2-3 hours and achieved selective oxidation of the primary alcohol groups of pullulan.
Article
Environmental Sciences
Maria Ioffe, Mingce Long, Adi Radian
Summary: A comparative activity assessment was conducted on various activated carbon and AC-Fe3O4 composites, revealing that persulfate-based systems showed higher pollutant removal in the presence of catalysts, while AC was able to completely mineralize bisphenol A through a non-radical pathway.
ENVIRONMENTAL RESEARCH
(2021)
Article
Engineering, Environmental
Jaemin Choi, Hak-Hyeon Kim, Ki-Myeong Lee, Na Chen, Min Sik Kim, Jiwon Seo, Donghyun Lee, Haein Cho, Hyoung-il Kim, Jaesang Lee, Hongshin Lee, Changha Lee
Summary: The generation of hydroxyl radicals by visible light-illuminated tungsten oxide is significantly improved in the presence of hydrogen peroxide and bicarbonate ion. The ternary system shows synergistic enhancement in benzoic acid oxidation, with less consumption of hydrogen peroxide compared to the binary system.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Chemistry, Multidisciplinary
Demin Kong, Lei Wang, Xiaoqian Chen, Wei Xia, Lingqia Su, Fangyuan Zuo, Zhengfei Yan, Sheng Chen, Jing Wu
Summary: This study proposes a new method for the degradation of polyethylene by introducing lipase and cutinase, which effectively reduces the molecular weight of polyethylene.
Article
Chemistry, Multidisciplinary
Shaokang Jia, Shixi Yang, Huimin Ji, Shuang Peng, Kun Chen, Zhiyong He, Xiang Zhou
CHINESE CHEMICAL LETTERS
(2020)
Article
Chemistry, Multidisciplinary
Yuqi Chen, Fan Wu, Zonggui Chen, Zhiyong He, Qi Wei, Weiwu Zeng, Kun Chen, Feng Xiao, Yushu Yuan, Xiaocheng Weng, Yu Zhou, Xiang Zhou
Article
Biochemistry & Molecular Biology
Pu Guo, Abdelbasset A. Farahat, Ananya Paul, Arvind Kumar, David W. Boykin, W. David Wilson
Article
Chemistry, Analytical
Yalun Xie, Yafen Wang, Zhiyong He, Wei Yang, Boshi Fu, Guangrong Zou, Xiong Zhang, Jinguo Huang, Xiang Zhou
ANALYTICAL CHEMISTRY
(2020)
Article
Chemistry, Multidisciplinary
Kun Chen, Zhiyong He, Wei Xiong, Chun-Jiang Wang, Xiang Zhou
Summary: This study utilized left-handed G-quadruplex (L-G4) structure to catalyze enantioselective reactions, showing good enantioselectivity under certain conditions and further enhanced enantioselectivity with the addition of G4 ligands. Ligands that have regulatory effects on G4 can adjust the enantiomeric excess (ee) value of the product.
CHINESE CHEMICAL LETTERS
(2021)
Article
Chemistry, Analytical
Kun Chen, Guangrong Zou, Wei Xiong, Zhiyong He, Shen Yan, Shanshan Qin, Qi Wang, Hengjiang Cong, Chun-Jiang Wang, Xiang Zhou
Summary: The study introduces a novel method combining aptamer binding and catalytic reactions to regulate drug release under pathological conditions, reducing drug toxicity and showing great potential for application in cancer treatment.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Biochemical Research Methods
Yalun Xie, Zhentian Fang, Wei Yang, Zhiyong He, Kun Chen, Panpan Heng, Baoshan Wang, Xiang Zhou
Summary: Natural modified bases in RNA play a crucial role in basic biological processes, and artificial RNA modifications have been widely used for studying RNA interference, structure, and dynamics. This study presents a chemical method for the synthesis of RNA containing C-6 modified purine, which provides a convenient approach for synthesizing oligonucleotides with specific structures.
BIOCONJUGATE CHEMISTRY
(2022)
Article
Engineering, Chemical
Zhen Luo, Chunhong Ye, Heng Xiao, Jialing Yin, Yicong Liang, Zhihui Ruan, Danju Luo, Daolong Gao, Qiuping Tan, Yongkui Li, Qiwei Zhang, Weiyong Liu, Jianguo Wu
Summary: In this study, an optimized LAMP assay was designed based on the N gene of SARS-CoV-2, which showed high efficiency, robustness, and visual detection capability. The assay was applicable for the detection of emerging SARS-CoV-2 variants.
CHEMICAL ENGINEERING SCIENCE
(2022)
Article
Chemistry, Medicinal
Giri R. Gnawali, Koichi Okumura, Karolina Perez, Rosa Gallagher, Julia Wulfkuhle, Emanuel F. Petricoin, Sathish Kumar Reddy Padi, Jeremiah Bearss, Zhiyong He, Wei Wang, Andrew S. Kraft
Summary: Compound VBT-5445 was identified as an inhibitor that blocks the association between Pim and EDC3. The activity of this compound class can be fine-tuned by structural modification, and some derivatives have shown high potency in inhibiting tumor growth.
MEDICINAL CHEMISTRY RESEARCH
(2022)
Review
Biochemistry & Molecular Biology
Tingting Yao, Heng Xiao, Hong Wang, Xiaowei Xu
Summary: Proteolysis-targeting chimera (PROTAC) is a promising molecule that degrades specific proteins through the ubiquitin-proteasome system. It has shown remarkable efficacy in various fields and opened up new avenues for biomedical research and development.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Virology
Zhiwei Lei, Leqing Zhu, Pan Pan, Zhihui Ruan, Yu Gu, Xichun Xia, Shengli Wang, Weiwei Ge, Yangrong Yao, Fazeng Luo, Heng Xiao, Jun Guo, Qiang Ding, Zhinan Yin, Yongkui Li, Zhen Luo, Qiwei Zhang, Xin Chen, Jianguo Wu
Summary: A vaccine delivery system has been developed to enhance durable cellular and humoral immune responses against broad SARS-CoV-2 variants.
JOURNAL OF MEDICAL VIROLOGY
(2023)
Article
Biochemistry & Molecular Biology
Qi Wei, Shaoqing Han, Kexin Yuan, Zhiyong He, Yuqi Chen, Xin Xi, Jingyu Han, Shen Yan, Yingying Chen, Bifeng Yuan, Xiaocheng Weng, Xiang Zhou
Summary: A new method was developed to enrich inosine-containing RNA and accurately identify editing sites using Endonuclease V and sodium periodate. The method was validated in the human brain and revealed that A-to-I editing primarily occurs in the 3'UTR of RNA. Comparison between human and mouse brain editing sites showed higher conservation in exons. Application of the method in mouse brain diseases revealed decreased editing in neuronal activity genes.
NUCLEIC ACIDS RESEARCH
(2023)
Article
Chemistry, Multidisciplinary
Pu Guo, Abdelbasset A. Farahat, Ananya Paul, David W. Boykin, W. David Wilson
Summary: This report describes a breakthrough in designing minor groove binders to recognize any sequence of DNA, successfully designing compound DB2831 to efficiently bind with the target DNA sequence and revealing its binding mechanism.
Article
Chemistry, Multidisciplinary
Heng Xiao, Huiling Fan, Luming Xu, Zhiyin Pei, Shijun Lei, Jinglei Xu, Jiangbo Xi, Guobin Wang, Lin Wang, Zheng Wang
CHEMICAL COMMUNICATIONS
(2019)
Article
Chemistry, Multidisciplinary
Zhiyong He, Shuang Peng, Qi Wei, Shaokang Jia, Shan Guo, Kun Chen, Xiang Zhou
Article
Chemistry, Multidisciplinary
Alexander M. Prophet, Kritanjan Polley, Gary J. Van Berkel, David T. Limmer, Kevin R. Wilson
Summary: The oxidation kinetics of iodide by ozone at the air-water interface is studied in single microdroplets. Molecular simulations and kinetic modeling are used to understand the underlying multiphase mechanism.
Article
Chemistry, Multidisciplinary
Rong Zhang, Jiajing Lan, Fei Wang, Shumei Chen, Jian Zhang
Summary: By utilizing 1,1'-ferrocene dicarboxylic acid as a chelating and surface protection ligand, we have synthesized multi-nuclear indium oxide clusters with varying nuclear sizes, including heptanuclear and thirteen-nuclear clusters. These clusters possess labile coordination sites, allowing for structural modification and self-assembly, resulting in the formation of various cluster structures.
Article
Chemistry, Multidisciplinary
Hui Wang, Hui Liu, Mingsen Wang, Jiaheng Hou, Yongjun Li, Yuancheng Wang, Yingjie Zhao
Summary: Two supramolecular complexes were prepared using CBs and M1, and their single-crystal structures were analyzed by SCXRD. The unexpected 1:2 self-assembly structure between M1 and CB[8] was discovered for the first time. These complexes exhibit unique photophysical properties and provide valuable information about the structure and photophysical properties of supramolecular complexes.
Article
Chemistry, Multidisciplinary
Chang-Hee Lee, Sookil Park, Sanggil Kim, Ji Young Hyun, Hyun Soo Lee, Injae Shin
Summary: The epidermal growth factor receptor (EGFR) is a cell-surface glycoprotein involved in cell proliferation and tumor development. This study used a fluorescently labeled EGFR to investigate its time-dependent endocytosis in live cells and found that appended glycans affect EGFR internalization. Additionally, the study detected sialic acid residues attached to EGFR on the live cell surface using FRET-based imaging. This research provides valuable insights into the cellular functions of EGFR.
Article
Chemistry, Multidisciplinary
Subhankar Sahu, Lokesh Kumar, Sumita Das, Dipti Gupta, Ruchi Anand
Summary: This study proposes a strategy that combines organic electronics with biosensor scaffolds to create a compact device for monitoring environmental aromatic pollution. By coupling biosensing protein MopR with an organic electrochemical transistor (OECT), a sensor module capable of efficient detection of phenol was designed. Exclusive phenol detection with minimal loss of sensitivity could be achieved in complex pollutant mixtures and real environmental samples.
Review
Chemistry, Multidisciplinary
Changseok Lee, Hyung-Joon Kang, Sungwoo Hong
Summary: The formation of C-N bonds through hydroamination reactions catalyzed by nickel hydrides has been a topic of recent interest. This approach offers a way to efficiently transform a variety of alkene and alkyne substrates into compounds enriched with C-N bonds. The review provides a concise overview of the underlying reaction mechanisms and aims to stimulate further progress in NiH-catalytic techniques and catalyst design.
Article
Chemistry, Multidisciplinary
Yueci Wu, Lu-Lu Sun, Hai-Hao Han, Xiao-Peng He, Weiguo Cao, Tony D. James
Summary: Drug-induced liver injury (DILI) is a common cause of acute liver failure in the USA and Europe, but most cases can be recovered or prevented by discontinuing the offending drug. Recent research has found that peroxynitrite (ONOO-) can be used as a potential indicator for early diagnosis of DILI, and there is an urgent need to establish a method to detect and track peroxynitrite in DILI cases. In this study, a FRET-based nano fluorescent probe CD-N-I was developed, which showed high selectivity and sensitivity in detecting peroxynitrite. The probe successfully detected exogenous peroxynitrite in live cells and endogenous peroxynitrite in APAP-induced liver injury of HepG2 cells.
Article
Chemistry, Multidisciplinary
Dmitry L. Lipilin, Mikhail O. Zubkov, Mikhail D. Kosobokov, Alexander D. Dilman
Summary: This article describes a direct photocatalytic method for the thiolation of unprotected acids, which was previously challenging. By using a thionocarbonate reagent with an N-O bond, the efficient conversion of carboxylic acids to thiols is achieved.
Article
Chemistry, Multidisciplinary
Jason Malenfant, Lucille Kuster, Yohann Gagne, Kouassi Signo, Maxime Denis, Sylvain Canesi, Mathieu Frenette
Summary: Raman microscopy can reveal compound-specific vibrational fingerprints without sample preparation. The combination of efficient theoretical calculations and a user-friendly software can accurately predict peak positions and provide match scores to assist with structure determination.
Article
Chemistry, Multidisciplinary
Jayoh A. Hernandez, Paul S. Micus, Sean Alec Lois Sunga, Luca Mazzei, Stefano Ciurli, Gabriele Meloni
Summary: Essential trace metals play crucial roles in the survival and virulence of bacterial pathogens. Helicobacter pylori requires nickel for colonization and persistence in the stomach, and NixA is an essential nickel transporter in this process. This study characterizes the selectivity and electrogenic nature of NixA-mediated nickel transport.
Article
Chemistry, Multidisciplinary
Tarali Devi, Kuheli Dutta, Jennifer Deutscher, Stefan Mebs, Uwe Kuhlmann, Michael Haumann, Beatrice Cula, Holger Dau, Peter Hildebrandt, Kallol Ray
Summary: This study emphasizes the importance of subtle electronic changes and secondary interactions in the stability of biologically relevant metal-dioxygen intermediates. It also shows that the role of the chloride ligand in stabilizing the Fe-III-(OOBu)-Bu-t moiety can extend to other anions, including the thiolate ligand.
Article
Chemistry, Multidisciplinary
Jacqueline R. Santhouse, Jeremy M. G. Leung, Lillian T. Chong, W. Seth Horne
Summary: By studying the folding kinetics and mechanism of the BdpA sequence, researchers found that altering the backbone connectivity can affect protein folding. This suggests that protein mimetic chains have a significant degree of plasticity in transitioning between unfolded and folded states.
Article
Chemistry, Multidisciplinary
Divanshu Gupta, Ralf Einholz, Holger F. Bettinger
Summary: This study presents the first direct spectroscopic evidence of a cyclic seven-membered iminoborane. Compared to linear amino-iminoboranes, this cyclic iminoborane exhibits weakened bond strength and lower Lewis acidity value. The study suggests that the reduced ring strain of cyclic iminoborane prevents nitrogen fixation but allows facile (2 + 2) cycloaddition reaction with C2H4.
Article
Chemistry, Multidisciplinary
Renny Mathew, Aniruddha Mazumder, Praveen Kumar, Julie Matula, Sharmarke Mohamed, Petr Brazda, Mahesh Hariharan, Brijith Thomas
Summary: This study reveals the packing arrangement of partially disordered nitro-perylenediimide (NO2-PDI) using a synergistic approach that combines 3D ED, ssNMR, and DFT techniques. By overcoming these challenges, this methodology opens up new avenues for material characterization, driving exciting advancements in the field.
