Levels of DNA Methylation Vary at CpG Sites across the BRCA1 Promoter, and Differ According to Triple Negative and “BRCA-Like” Status, in Both Blood and Tumour DNA
出版年份 2016 全文链接
标题
Levels of DNA Methylation Vary at CpG Sites across the BRCA1 Promoter, and Differ According to Triple Negative and “BRCA-Like” Status, in Both Blood and Tumour DNA
作者
关键词
DNA methylation, Genetic causes of cancer, Blood, Breast tumors, Protein expression, Breast cancer, Breast tissue, Mutation
出版物
PLoS One
Volume 11, Issue 7, Pages e0160174
出版商
Public Library of Science (PLoS)
发表日期
2016-07-28
DOI
10.1371/journal.pone.0160174
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Ovarian cancer: Status of homologous recombination pathway as a predictor of drug response
- (2016) Nicolas De Picciotto et al. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
- Hypermethylation of BRCA1 gene: implication for prognostic biomarker and therapeutic target in sporadic primary triple-negative breast cancer
- (2015) X. Zhu et al. BREAST CANCER RESEARCH AND TREATMENT
- Aberrant DNA methylation impacts gene expression and prognosis in breast cancer subtypes
- (2015) Balázs Győrffy et al. INTERNATIONAL JOURNAL OF CANCER
- BRCA1-like signature in triple negative breast cancer: Molecular and clinical characterization reveals subgroups with therapeutic potential
- (2015) Tesa M. Severson et al. Molecular Oncology
- Association of BRCA1 promoter methylation with sporadic breast cancers: Evidence from 40 studies
- (2015) Li Zhang et al. Scientific Reports
- Promoter Hypermethylation in White Blood Cell DNA and Breast Cancer Risk
- (2015) Yoon Hee Cho et al. Journal of Cancer
- Comprehensive Genomic Analysis Identifies Novel Subtypes and Targets of Triple-Negative Breast Cancer
- (2014) M. D. Burstein et al. CLINICAL CANCER RESEARCH
- TumourMLH1promoter region methylation testing is an effective prescreen for Lynch Syndrome (HNPCC)
- (2014) K Newton et al. JOURNAL OF MEDICAL GENETICS
- BRCA1 promoter methylation is a marker of better response to anthracycline-based therapy in sporadic TNBC
- (2013) T. Ignatov et al. BREAST CANCER RESEARCH AND TREATMENT
- Platform comparisons for identification of breast cancers with a BRCA-like copy number profile
- (2013) Philip C. Schouten et al. BREAST CANCER RESEARCH AND TREATMENT
- Promoter methylation of BRCA1 in the prognosis of breast cancer: a meta-analysis
- (2013) Liang Wu et al. BREAST CANCER RESEARCH AND TREATMENT
- Pyrosequencing analysis of BRCA1 methylation level in breast cancer cells
- (2013) Fengfeng Cai et al. TUMOR BIOLOGY
- Evaluation of BRCA1 mutations in an unselected patient population with triple-negative breast cancer
- (2012) Seth Rummel et al. BREAST CANCER RESEARCH AND TREATMENT
- Intragenic ATM Methylation in Peripheral Blood DNA as a Biomarker of Breast Cancer Risk
- (2012) K. Brennan et al. CANCER RESEARCH
- Detection of promoter methylation of tumor suppressor genes in serum DNA of breast cancer cases and benign breast disease controls
- (2012) Susan R. Sturgeon et al. Epigenetics
- BRCA1-methylated sporadic breast cancers are BRCA-like in showing a basal phenotype and absence of ER expression
- (2012) Amanjit Bal et al. VIRCHOWS ARCHIV
- Morphological predictors of BRCA1 germline mutations in young women with breast cancer
- (2011) M C Southey et al. BRITISH JOURNAL OF CANCER
- CpG island hypermethylation ofBRCA1and loss of pRb as co-occurring events in basal/triple-negative breast cancer
- (2011) Olafur Andri Stefansson et al. Epigenetics
- DNA methylation in white blood cells
- (2011) Mary Beth Terry et al. Epigenetics
- Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies
- (2011) Brian D. Lehmann et al. JOURNAL OF CLINICAL INVESTIGATION
- Prevalence of BRCA1 and BRCA2 mutations in triple negative breast cancer
- (2011) D. G. Evans et al. JOURNAL OF MEDICAL GENETICS
- Methylation profiles of the BRCA1 promoter in hereditary and sporadic breast cancer among Han Chinese
- (2011) Da Pang et al. MEDICAL ONCOLOGY
- Triple-Negative Breast Cancer: An Unmet Medical Need
- (2011) C. A. Hudis et al. ONCOLOGIST
- Molecular Stratification of Triple-Negative Breast Cancers
- (2011) C. M. Perou ONCOLOGIST
- Using tumour pathology to identify people at high genetic risk of breast and colorectal cancers
- (2011) J.L. Hopper et al. PATHOLOGY
- Constitutional Methylation of the BRCA1 Promoter Is Specifically Associated with BRCA1 Mutation-Associated Pathology in Early-Onset Breast Cancer
- (2010) E. M. Wong et al. Cancer Prevention Research
- BRCA1 CpG Island Hypermethylation Predicts Sensitivity to Poly(Adenosine Diphosphate)- Ribose Polymerase Inhibitors
- (2010) Jurgen Veeck et al. JOURNAL OF CLINICAL ONCOLOGY
- Basal-like and triple-negative breast cancers: a critical review with an emphasis on the implications for pathologists and oncologists
- (2010) Sunil Badve et al. MODERN PATHOLOGY
- High Frequency of TP53 Mutation in BRCA1 and Sporadic Basal-like Carcinomas but not in BRCA1 Luminal Breast Tumors
- (2009) E. Manie et al. CANCER RESEARCH
- Triple-negative breast cancer: clinicopathological characteristics and relationship with basal-like breast cancer
- (2009) Aye Aye Thike et al. MODERN PATHOLOGY
- BRCA1 promoter methylation is associated with increased mortality among women with breast cancer
- (2008) Xinran Xu et al. BREAST CANCER RESEARCH AND TREATMENT
- Breast cancer special types: why bother?
- (2008) JS Reis-Filho et al. JOURNAL OF PATHOLOGY
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