Stearoyl-CoA Desaturase 1 Is a Key Determinant of Membrane Lipid Composition in 3T3-L1 Adipocytes

SCD1 inhibition during 3T3-L1 adipocyte differentiation remodels triacylglycerol, diacylglycerol and phospholipid fatty acid composition

(2015) Jessica C. Ralston et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

4-Bicyclic heteroaryl-piperidine derivatives as potent, orally bioavailable stearoyl-CoA desaturase-1 (SCD1) inhibitors: Part 2. Pyridazine-based analogs

(2014) Shyh-Ming Yang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Inhibition of stearoyl-CoA desaturase-1 in differentiating 3T3-L1 preadipocytes upregulates elongase 6 and downregulates genes affecting triacylglycerol synthesis

(2014) J C Ralston et al.   INTERNATIONAL JOURNAL OF OBESITY

Lipid composition of membrane rafts, isolated with and without detergent, from the spleen of a mouse model of Gaucher disease

(2013) Kathryn J. Hattersley et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Adaptive Changes of the Insig1/SREBP1/SCD1 Set Point Help Adipose Tissue to Cope With Increased Storage Demands of Obesity

(2013) S. Carobbio et al.   DIABETES

Selective reduction of bis(monoacylglycero)phosphate ameliorates the storage burden in a THP-1 macrophage model of Gaucher disease

(2013) Leanne K. Hein et al.   JOURNAL OF LIPID RESEARCH

Trans-vaccenate is Δ13-desaturated by FADS3 in rodents

(2013) Vincent Rioux et al.   JOURNAL OF LIPID RESEARCH

SCD1 activity in muscle increases triglyceride PUFA content, exercise capacity, and PPARδ expression in mice

(2013) Michael P. Rogowski et al.   JOURNAL OF LIPID RESEARCH

Sterculic Oil, a natural inhibitor of SCD1, improves the metabolic state of obese OLETF rats

(2013) L. C. Ortinau et al.   Obesity

Discovery of Piperazin-1-ylpyridazine-Based Potent and Selective Stearoyl-CoA Desaturase-1 Inhibitors for the Treatment of Obesity and Metabolic Syndrome

(2012) Zaihui Zhang et al.   JOURNAL OF MEDICINAL CHEMISTRY

The role of stearoyl-CoA desaturase in obesity, insulin resistance, and inflammation

(2011) Harini Sampath et al.   Annals of the New York Academy of Sciences

Membrane Organization and Lipid Rafts

(2011) K. Simons et al.   Cold Spring Harbor Perspectives in Biology

Adipose-specific deletion of stearoyl-CoA desaturase 1 up-regulates the glucose transporter GLUT1 in adipose tissue

(2010) Chang-Kee Hyun et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Separation and quantification of sn-1 and sn-2 fatty acid positional isomers in phosphatidylcholine by RPLC-ESIMS/MS

(2009) Hiroki Nakanishi et al.   JOURNAL OF BIOCHEMISTRY

Skin-specific Deletion of Stearoyl-CoA Desaturase-1 Alters Skin Lipid Composition and Protects Mice from High Fat Diet-induced Obesity

(2009) Harini Sampath et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

De NovoLipogenesis and Stearoyl-CoA Desaturase Are Coordinately Regulated in the Human Adipocyte and Protect against Palmitate-induced Cell Injury

(2009) Jennifer M. Collins et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Polyunsaturated fatty acid–cholesterol interactions: Domain formation in membranes

(2008) Stephen R. Wassall et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES