MPT0B098, a Microtubule Inhibitor, Suppresses JAK2/STAT3 Signaling Pathway through Modulation of SOCS3 Stability in Oral Squamous Cell Carcinoma

Characterization of STAT3 expression, signaling and inhibition in feline oral squamous cell carcinoma

(2015) Megan E. Brown et al.   BMC Veterinary Research

Combinatorial Effects of Curcumin with an Anti-Neoplastic Agent on Head and Neck Squamous Cell Carcinoma Through the Regulation of EGFR-ERK1/2 and Apoptotic Signaling Pathways

(2015) Banudevi Sivanantham et al.   ACS Combinatorial Science

Phase 1, open-label, dose-escalation, and pharmacokinetic study of STAT3 inhibitor OPB-31121 in subjects with advanced solid tumors

(2014) Johanna C. Bendell et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Downregulated miR329 and miR410 Promote the Proliferation and Invasion of Oral Squamous Cell Carcinoma by Targeting Wnt-7b

(2014) S.-G. Shiah et al.   CANCER RESEARCH

STAT3 Target Genes Relevant to Human Cancers

(2014) Richard Carpenter et al.   Cancers

MPT0B098, a Novel Microtubule Inhibitor That Destabilizes the Hypoxia-Inducible Factor-1  mRNA through Decreasing Nuclear-Cytoplasmic Translocation of RNA-Binding Protein HuR

(2013) Y.-C. Cheng et al.   MOLECULAR CANCER THERAPEUTICS

Induction chemotherapy with docetaxel, cisplatin and 5-fluorouracil followed by radiotherapy with cetuximab for locally advanced squamous cell carcinoma of the head and neck

(2012) Felix Keil et al.   EUROPEAN JOURNAL OF CANCER

Targeting the Interleukin-6/Jak/Stat Pathway in Human Malignancies

(2012) Pasquale Sansone et al.   JOURNAL OF CLINICAL ONCOLOGY

First-in-Human Trial of a STAT3 Decoy Oligonucleotide in Head and Neck Tumors: Implications for Cancer Therapy

(2012) Malabika Sen et al.   Cancer Discovery

Suppressors of Cytokine Signaling (SOCS) Proteins and JAK/STAT Pathways

(2011) Taiga Tamiya et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Stat3/Socs3 Activation by IL-6 Transsignaling Promotes Progression of Pancreatic Intraepithelial Neoplasia and Development of Pancreatic Cancer

(2011) Marina Lesina et al.   CANCER CELL

Induction chemotherapy with cisplatin and fluorouracil alone or in combination with docetaxel in locally advanced squamous-cell cancer of the head and neck: long-term results of the TAX 324 randomised phase 3 trial

(2011) Jochen H Lorch et al.   LANCET ONCOLOGY

Curcumin: A review of anti-cancer properties and therapeutic activity in head and neck squamous cell carcinoma

(2011) Reason Wilken et al.   Molecular Cancer

Stat3 Orchestrates Tumor Development and Progression: The Achilles Heel of Head and Neck Cancers?

(2010) M. Masuda et al.   CURRENT CANCER DRUG TARGETS

Prognostic significance of nuclear pSTAT3 in oral cancer

(2010) Muzafar A. Macha et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

FOXO3a reactivation mediates the synergistic cytotoxic effects of rapamycin and cisplatin in oral squamous cell carcinoma cells

(2010) Liang Fang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Synthesis and biological evaluation of 7-arylindoline-1-benzenesulfonamides as a novel class of potent anticancer agents

(2010) Jang-Yang Chang et al.   MedChemComm

Clinicopathological parameters, recurrence, locoregional and distant metastasis in 115 T1-T2 oral squamous cell carcinoma patients

(2010) Waseem Jerjes et al.   Head and Neck Optical Diagnostics Society

Requirement for microtubule integrity in the SOCS1-mediated intracellular dynamics of HIV-1 Gag

(2009) Mayuko Nishi et al.   FEBS LETTERS

Nifuroxazide inhibits survival of multiple myeloma cells by directly inhibiting STAT3

(2008) E. A. Nelson et al.   BLOOD

The role of microtubule-associated protein 1S in SOCS3 regulation of IL-6 signaling

(2008) Tingting Zou et al.   FEBS LETTERS

5-Fluorouracil: Mechanisms of Resistance and Reversal Strategies

(2008) Ning Zhang et al.   MOLECULES

Global epidemiology of oral and oropharyngeal cancer

(2008) Saman Warnakulasuriya   ORAL ONCOLOGY