Dominant Expression of DCLK1 in Human Pancreatic Cancer Stem Cells Accelerates Tumor Invasion and Metastasis

Epigenetic Priming of Enhancers Predicts Developmental Competence of hESC-Derived Endodermal Lineage Intermediates

(2015) Allen Wang et al.   Cell Stem Cell

An epigenetically distinct breast cancer cell subpopulation promotes collective invasion

(2015) Jill M. Westcott et al.   JOURNAL OF CLINICAL INVESTIGATION

Chromatin architecture reorganization during stem cell differentiation

(2015) Jesse R. Dixon et al.   NATURE

Pancreatic Adenocarcinoma

(2015) David P. Ryan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cancer statistics, 2014

(2014) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

XMD8-92 inhibits pancreatic tumor xenograft growth via a DCLK1-dependent mechanism

(2014) Sripathi M. Sureban et al.   CANCER LETTERS

Neutralizing Murine TGF R2 Promotes a Differentiated Tumor Cell Phenotype and Inhibits Pancreatic Cancer Metastasis

(2014) K. T. Ostapoff et al.   CANCER RESEARCH

Curcumin Promotes Autophagic Survival of a Subset of Colon Cancer Stem Cells, Which Are Ablated by DCLK1-siRNA

(2014) C. Kantara et al.   CANCER RESEARCH

Metastatic Stem Cells: Sources, Niches, and Vital Pathways

(2014) Thordur Oskarsson et al.   Cell Stem Cell

Spontaneous development of hepatocellular carcinoma with cancer stem cell properties in PR-SET7-deficient livers

(2014) K. C. Nikolaou et al.   EMBO JOURNAL

Long-lived intestinal tuft cells serve as colon cancer–initiating cells

(2014) C. Benedikt Westphalen et al.   JOURNAL OF CLINICAL INVESTIGATION

Small molecule kinase inhibitor LRRK2-IN-1 demonstrates potent activity against colorectal and pancreatic cancer through inhibition of doublecortin-like kinase 1

(2014) Nathaniel Weygant et al.   Molecular Cancer

Analysis of the tumor-initiating and metastatic capacity of PDX1-positive cells from the adult pancreas

(2014) Irene Ischenko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Use of human embryonic stem cells to model pediatric gliomas with H3.3K27M histone mutation

(2014) Kosuke Funato et al.   SCIENCE

Epigenetic Regulation by Chromatin Activation Mark H3K4me3 in Primate Progenitor Cells within Adult Neurogenic Niche

(2014) Richard S. Sandstrom et al.   Scientific Reports

DCLK1 Marks a Morphologically Distinct Subpopulation of Cells With Stem Cell Properties in Preinvasive Pancreatic Cancer

(2013) Jennifer M. Bailey et al.   GASTROENTEROLOGY

Visualization of stem cell features in human hepatocellular carcinoma revealsin vivosignificance of tumor-host interaction and clinical course

(2013) Shunsuke Muramatsu et al.   HEPATOLOGY

In vivo serial selection of human pancreatic cancer cells in orthotopic mouse models produces high metastatic variants irrespective of Kras status

(2013) Cristina A. Metildi et al.   JOURNAL OF SURGICAL RESEARCH

High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy

(2013) Samuel A. Hasson et al.   NATURE

Small molecule inhibition of the KRAS–PDEδ interaction impairs oncogenic KRAS signalling

(2013) Gunther Zimmermann et al.   NATURE

Self-renewal as a therapeutic target in human colorectal cancer

(2013) Antonija Kreso et al.   NATURE MEDICINE

Doublecortin-like kinase enhances dendritic remodelling and negatively regulates synapse maturation

(2013) Euikyung Shin et al.   Nature Communications

An Aberrant Transcription Factor Network Essential for Wnt Signaling and Stem Cell Maintenance in Glioblastoma

(2013) Esther Rheinbay et al.   Cell Reports

Identification of Pancreatic Cancer Stem Cells and Selective Toxicity of Chemotherapeutic Agents

(2012) Rama Adikrisna et al.   GASTROENTEROLOGY

The evolving concept of cancer and metastasis stem cells

(2012) Irène Baccelli et al.   JOURNAL OF CELL BIOLOGY

In vitro cell migration and invasion assays

(2012) Nina Kramer et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

(2012) Andrew V. Biankin et al.   NATURE

Dclk1 distinguishes between tumor and normal stem cells in the intestine

(2012) Yuki Nakanishi et al.   NATURE GENETICS

DCAMKL-1 Regulates Epithelial-Mesenchymal Transition in Human Pancreatic Cells through a miR-200a-Dependent Mechanism

(2011) S. M. Sureban et al.   CANCER RESEARCH

A Perspective on Cancer Cell Metastasis

(2011) C. L. Chaffer et al.   SCIENCE

Silencing of the microtubule-associated proteins doublecortin-like and doublecortin-like kinase-long induces apoptosis in neuroblastoma cells

(2010) Carla S Verissimo et al.   ENDOCRINE-RELATED CANCER

A Proteomic Approach for Comprehensively Screening Substrates of Protein Kinases Such as Rho-Kinase

(2010) Mutsuki Amano et al.   PLoS One

Selective Blockade of DCAMKL-1 Results in Tumor Growth Arrest by a Let-7a MicroRNA-Dependent Mechanism

(2009) Sripathi M. Sureban et al.   GASTROENTEROLOGY

In Vivo Imaging, Tracking, and Targeting of Cancer Stem Cells

(2009) Erina Vlashi et al.   JNCI-Journal of the National Cancer Institute

Role of cancer stem cells in pancreatic ductal adenocarcinoma

(2009) Gregory Sergeant et al.   Nature Reviews Clinical Oncology

Pancreatic Cancer Stem Cells: Implications for the Treatment of Pancreatic Cancer

(2008) D. M. Simeone   CLINICAL CANCER RESEARCH

Production of neurons, astrocytes and oligodendrocytes from mammalian CNS stem cells

(2008) Andrew Chojnacki et al.   Nature Protocols

Identification of a Novel Putative Gastrointestinal Stem Cell and Adenoma Stem Cell Marker, Doublecortin and CaM Kinase-Like-1, Following Radiation Injury and in Adenomatous Polyposis Coli/Multiple Intestinal Neoplasia Mice

(2007) Randal May et al.   STEM CELLS